JOP20210170A1 - طرق وتركيبات لعلاج اضطرابات الجلد والشعر - Google Patents

طرق وتركيبات لعلاج اضطرابات الجلد والشعر

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Publication number
JOP20210170A1
JOP20210170A1 JOP/2021/0170A JOP20210170A JOP20210170A1 JO P20210170 A1 JOP20210170 A1 JO P20210170A1 JO P20210170 A JOP20210170 A JO P20210170A JO P20210170 A1 JOP20210170 A1 JO P20210170A1
Authority
JO
Jordan
Prior art keywords
skin
hair
methods
compositions
color
Prior art date
Application number
JOP/2021/0170A
Other languages
English (en)
Inventor
Kenneth Allen Pettine
Timothy Alexander Moseley
Original Assignee
Direct Biologics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Direct Biologics Llc filed Critical Direct Biologics Llc
Publication of JOP20210170A1 publication Critical patent/JOP20210170A1/ar

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/985Skin or skin outgrowth, e.g. hair, nails
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)

Abstract

يتم الكشف عن تركيبات عامل نمو الخلية الجذعية اللحمية المتوسطة وطرق استخدامها في علاج اضطرابات الجلد، وشيب الشعر، والصلع، وخلل الانتصاب إضافةً إلى استخدامها في العلاجات الجلدية والتجميلية النوعية للون الجلد/العِرق. في بعض الجوانب، يستهدف العلاج SNPs نوعية للون الشعر، و/أو لون الجلد، و/أو نوع الجلد، و/أو نوع الشعر، و/أو الجنس، و/أو العِرق و/أو الاستجابة للتستوستيرون.
JOP/2021/0170A 2018-12-26 2019-12-26 طرق وتركيبات لعلاج اضطرابات الجلد والشعر JOP20210170A1 (ar)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862785072P 2018-12-26 2018-12-26
US201862785155P 2018-12-26 2018-12-26
US201862785126P 2018-12-26 2018-12-26
US201962787672P 2019-01-02 2019-01-02
PCT/US2019/068615 WO2020139975A1 (en) 2018-12-26 2019-12-26 Methods and compositions for treating skin and hair disorders

Publications (1)

Publication Number Publication Date
JOP20210170A1 true JOP20210170A1 (ar) 2023-01-30

Family

ID=71129813

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2021/0170A JOP20210170A1 (ar) 2018-12-26 2019-12-26 طرق وتركيبات لعلاج اضطرابات الجلد والشعر

Country Status (13)

Country Link
US (1) US20220079990A1 (ar)
EP (1) EP3902605A4 (ar)
JP (1) JP2022516607A (ar)
KR (1) KR20210121039A (ar)
AU (1) AU2019416339A1 (ar)
BR (1) BR112021012661A2 (ar)
CA (1) CA3124949A1 (ar)
IL (1) IL284377A (ar)
JO (1) JOP20210170A1 (ar)
MX (1) MX2021007885A (ar)
SG (1) SG11202106836UA (ar)
WO (1) WO2020139975A1 (ar)
ZA (1) ZA202104737B (ar)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202108129SA (en) * 2019-01-30 2021-08-30 Direct Biologics Llc Methods and compositions for developing target specific exosome and growth factor products
US20220347220A1 (en) * 2021-04-28 2022-11-03 Brian Liljenquist Formulations and methods for activating signaling molecules outside a native physiological response
CN114832015A (zh) * 2022-04-22 2022-08-02 西安初源赛尔生物科技有限责任公司 一种基于prp与干细胞外泌体的面部修复注射剂及其制备方法
CN115040542B (zh) * 2022-08-15 2022-11-18 山东卓东生物科技有限公司 外泌体与视黄醛的混合物作为制备治疗皮肤橘皮组织药物上的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1062321B1 (en) * 1998-03-13 2004-12-29 Osiris Therapeutics, Inc. Uses for humane non-autologous mesenchymal stem cells
US20090304644A1 (en) * 2006-05-30 2009-12-10 Cytori Therapeutics, Inc. Systems and methods for manipulation of regenerative cells separated and concentrated from adipose tissue
WO2007149548A2 (en) * 2006-06-22 2007-12-27 Medistem Laboratories, Inc. Treatment of erectile dysfunction by stem cell therapy
WO2010111522A2 (en) * 2009-03-26 2010-09-30 The Regents Of The University Of California Mesenchymal stem cells producing inhibitory rna for disease modification
JP6071875B2 (ja) * 2010-06-18 2017-02-08 ザ ヘンリー エム.ジャクソン ファウンデイション フォー ザ アドバンスメント オブ ミリタリー メディスン,インコーポレイティド 毛包新生
AU2012328353B2 (en) * 2011-10-27 2017-05-25 Universitat Leipzig Method for deriving melanocytes from the hair follicle outer root sheath and preparation for grafting
JP2015510884A (ja) * 2012-03-07 2015-04-13 ファイブロセル テクノロジーズ, インコーポレイテッド 局所的皮膚用製剤および皮膚の個人向けの処置方法
WO2014005183A1 (en) * 2012-07-04 2014-01-09 The University Of Sydney Treatment of inflammatory skin disorders
CA3017571A1 (en) * 2015-03-16 2016-09-22 Duncan Ross Method of treatment comprising membrane-enclosed vesicle
US20180318356A1 (en) * 2016-12-29 2018-11-08 Kenneth Allen Pettine Dermatological and cosmetic treatments using mesenchymal stem cells
CN108042572A (zh) * 2017-12-27 2018-05-18 北京多赢时代转化医学研究院 治疗白癜风的产品及其使用方法和应用
CN108498452A (zh) * 2018-04-10 2018-09-07 上海交通大学医学院附属仁济医院 一种用于治疗***功能障碍的含干细胞可注射水凝胶及其制备方法
WO2019231562A1 (en) * 2018-05-30 2019-12-05 Direct Biologics Llc A growth factor and extracellular vesicle frozen or powdered additive comprising a mesenchymal stem cell (msc) preparation and methods of use

Also Published As

Publication number Publication date
KR20210121039A (ko) 2021-10-07
US20220079990A1 (en) 2022-03-17
EP3902605A4 (en) 2022-09-28
CA3124949A1 (en) 2020-07-02
IL284377A (en) 2021-08-31
EP3902605A1 (en) 2021-11-03
ZA202104737B (en) 2022-06-29
AU2019416339A1 (en) 2021-07-22
SG11202106836UA (en) 2021-07-29
WO2020139975A1 (en) 2020-07-02
MX2021007885A (es) 2021-10-01
BR112021012661A2 (pt) 2021-09-08
JP2022516607A (ja) 2022-03-01

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