JO3769B1 - RNAi Therapy for Hepatitis B Virus Infection - Google Patents

RNAi Therapy for Hepatitis B Virus Infection

Info

Publication number
JO3769B1
JO3769B1 JOP/2016/0170A JOP20160170A JO3769B1 JO 3769 B1 JO3769 B1 JO 3769B1 JO P20160170 A JOP20160170 A JO P20160170A JO 3769 B1 JO3769 B1 JO 3769B1
Authority
JO
Jordan
Prior art keywords
hepatitis
virus infection
triggers
rnai
hbv
Prior art date
Application number
JOP/2016/0170A
Other languages
Arabic (ar)
Inventor
David B Rozema
David L Lewis
Lauren J Almeida
Darren H Wakefield
Christine I Wooddell
Original Assignee
Arrowhead Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arrowhead Pharmaceuticals Inc filed Critical Arrowhead Pharmaceuticals Inc
Application granted granted Critical
Publication of JO3769B1 publication Critical patent/JO3769B1/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

<strong>Described are compositions and methods for inhibition of Hepatitis B virus gene expression. RNA interference (RN Ai) triggers and RNAi trigger conjugates for inhibiting the expression of Hepatitis B virus gene are described. Pharmaceutical compositions comprising one or more HBV RNAi triggers optionally with one or more additional therapeutics are also described. Delivery of the described HBV RNAi triggers to infected liver in vivo provides for inhibition of HBV gene expression and treatment.</strong>
JOP/2016/0170A 2015-08-07 2016-08-04 RNAi Therapy for Hepatitis B Virus Infection JO3769B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562202253P 2015-08-07 2015-08-07

Publications (1)

Publication Number Publication Date
JO3769B1 true JO3769B1 (en) 2021-01-31

Family

ID=59687542

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2016/0170A JO3769B1 (en) 2015-08-07 2016-08-04 RNAi Therapy for Hepatitis B Virus Infection

Country Status (3)

Country Link
AR (1) AR105611A1 (en)
JO (1) JO3769B1 (en)
TW (2) TWI794884B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8501930B2 (en) * 2010-12-17 2013-08-06 Arrowhead Madison Inc. Peptide-based in vivo siRNA delivery system
JP6165723B2 (en) * 2011-06-30 2017-07-19 アローヘッド ファーマシューティカルズ インコーポレイテッド Compositions and methods for inhibiting gene expression of hepatitis B virus

Also Published As

Publication number Publication date
TW201717971A (en) 2017-06-01
TWI794884B (en) 2023-03-01
TW202142242A (en) 2021-11-16
AR105611A1 (en) 2017-10-18
TWI761308B (en) 2022-04-21

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