JO1832B1 - Theraputic agents - Google Patents

Abstract

Compounds of formula I and pharmaceutically acceptable salts thereof in Which R1, R2 and R3 independently represent hydrogen, hydro halo, alkyl or alkoxy; ALK1 represents a C2_6 alkylene chain optionally substituted by one or more C1-2 alkyl groups; Y represents a piperidine ring which is attached through nitrogen to ALK1; R4 represents hydrogen or a C1_4 alkyl group; the broken line in --- represents a bond, or is absent arid the free valency on Y is taken up by hydrog and the free valency on CR4 is taken up by hydrogen or C1_4 alkyl group; ALK2 is absent or represents a C1_4 alkylene chain optionally substituted by one or more C1_2 alkyl groups; and R5 and R6 independently represent hydrogen, alkyl, phenyl, alkyl (optionally substituted) or R5 and R6 together with the nitrogen atom to which they are attached represent a saturated 3-7 membered heterocyclic ring (with a proviso); are disclosed Which are antlinflammatory. antiallergic and immunomoclulatory agents. Compositions containing these compounds and processes to prepare these compounds are also disclosed.