ITUB20153108A1 - Varianti del recettore delle cellule T e loro uso nella terapia tumorale - Google Patents
Varianti del recettore delle cellule T e loro uso nella terapia tumoraleInfo
- Publication number
- ITUB20153108A1 ITUB20153108A1 ITUB2015A003108A ITUB20153108A ITUB20153108A1 IT UB20153108 A1 ITUB20153108 A1 IT UB20153108A1 IT UB2015A003108 A ITUB2015A003108 A IT UB2015A003108A IT UB20153108 A ITUB20153108 A IT UB20153108A IT UB20153108 A1 ITUB20153108 A1 IT UB20153108A1
- Authority
- IT
- Italy
- Prior art keywords
- variants
- cell receptor
- tumor therapy
- tumor
- therapy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47B—TABLES; DESKS; OFFICE FURNITURE; CABINETS; DRAWERS; GENERAL DETAILS OF FURNITURE
- A47B3/00—Folding or stowable tables
- A47B3/06—Folding or stowable tables with separable parts
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47B—TABLES; DESKS; OFFICE FURNITURE; CABINETS; DRAWERS; GENERAL DETAILS OF FURNITURE
- A47B13/00—Details of tables or desks
- A47B13/02—Underframes
- A47B13/021—Fastening devices of the feet or legs
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47B—TABLES; DESKS; OFFICE FURNITURE; CABINETS; DRAWERS; GENERAL DETAILS OF FURNITURE
- A47B21/00—Tables or desks for office equipment, e.g. typewriters, keyboards
- A47B21/06—Tables or desks for office equipment, e.g. typewriters, keyboards characterised by means for holding, fastening or concealing cables
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47B—TABLES; DESKS; OFFICE FURNITURE; CABINETS; DRAWERS; GENERAL DETAILS OF FURNITURE
- A47B13/00—Details of tables or desks
- A47B13/02—Underframes
- A47B13/021—Fastening devices of the feet or legs
- A47B2013/022—Fastening devices of the feet or legs with detachable connection of a tubular leg
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47B—TABLES; DESKS; OFFICE FURNITURE; CABINETS; DRAWERS; GENERAL DETAILS OF FURNITURE
- A47B2200/00—General construction of tables or desks
- A47B2200/0011—Underframes
- A47B2200/0019—Auxiliary use of table underframes, e.g. incorporating: cooling, drainage, air supply or wires
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITUB2015A003108A ITUB20153108A1 (it) | 2015-08-13 | 2015-08-13 | Varianti del recettore delle cellule T e loro uso nella terapia tumorale |
PCT/EP2015/075607 WO2016071343A1 (en) | 2014-11-03 | 2015-11-03 | T cell receptors |
US15/523,925 US20190030071A1 (en) | 2014-11-03 | 2015-11-03 | T cell receptors |
EP15790529.0A EP3215164A1 (en) | 2014-11-03 | 2015-11-03 | T cell receptors |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITUB2015A003108A ITUB20153108A1 (it) | 2015-08-13 | 2015-08-13 | Varianti del recettore delle cellule T e loro uso nella terapia tumorale |
Publications (1)
Publication Number | Publication Date |
---|---|
ITUB20153108A1 true ITUB20153108A1 (it) | 2017-02-13 |
Family
ID=54884144
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITUB2015A003108A ITUB20153108A1 (it) | 2014-11-03 | 2015-08-13 | Varianti del recettore delle cellule T e loro uso nella terapia tumorale |
Country Status (1)
Country | Link |
---|---|
IT (1) | ITUB20153108A1 (it) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6696545B1 (en) * | 1997-04-11 | 2004-02-24 | Sangstat Medical Corporation | Cytomodulating lipophilic peptides for modulating immune system activity and inhibiting inflammation |
-
2015
- 2015-08-13 IT ITUB2015A003108A patent/ITUB20153108A1/it unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6696545B1 (en) * | 1997-04-11 | 2004-02-24 | Sangstat Medical Corporation | Cytomodulating lipophilic peptides for modulating immune system activity and inhibiting inflammation |
Non-Patent Citations (5)
Title |
---|
AGGEN D H ET AL: "Single-chain V alpha V beta T-cell receptors function without mispairing with endogenous TCR chains", GENE THERAPY, vol. 19, no. 4, April 2012 (2012-04-01), pages 365 - 374, XP002754589 * |
MORLEY B J ET AL: "THE LYSINE RESIDUE IN THE MEMBRANE-SPANNING DOMAIN OF THE BETA CHAIN IS NECESSARY FOR CELL SURFACE EXPRESSION OF THE T CELL ANTIGEN RECEPTOR", JOURNAL OF EXPERIMENTAL MEDICINE, vol. 168, no. 6, 1988, pages 1971 - 1978, XP002754591, ISSN: 0022-1007 * |
OKAMOTO SACHIKO ET AL: "Improved Expression and Reactivity of Transduced Tumor-Specific TCRs in Human Lymphocytes by Specific Silencing of Endogenous TCR", CANCER RESEARCH, vol. 69, no. 23, December 2009 (2009-12-01), pages 9003 - 9011, XP002754590, ISSN: 0008-5472 * |
VARRIALE S ET AL: "An evolutionary conserved motif is responsible for Immunoglobulin heavy chain packing in the B cell membrane", MOLECULAR PHYLOGENETICS AND EVOLUTION, ORLANDO, FL, US, vol. 57, no. 3, 1 December 2010 (2010-12-01), pages 1238 - 1244, XP027534534, ISSN: 1055-7903, [retrieved on 20101016] * |
Z. SEBESTYEN ET AL: "Human TCR That Incorporate CD3 Induce Highly Preferred Pairing between TCR and Chains following Gene Transfer", THE JOURNAL OF IMMUNOLOGY, vol. 180, no. 11, 19 May 2008 (2008-05-19), pages 7736 - 7746, XP055118197, ISSN: 0022-1767, DOI: 10.4049/jimmunol.180.11.7736 * |
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