ITRM960364A0 - Agente attivo terapeutico per il trattamento di malattie degenerative neuronali. - Google Patents
Agente attivo terapeutico per il trattamento di malattie degenerative neuronali.Info
- Publication number
- ITRM960364A0 ITRM960364A0 ITRM960364A ITRM960364A ITRM960364A0 IT RM960364 A0 ITRM960364 A0 IT RM960364A0 IT RM960364 A ITRM960364 A IT RM960364A IT RM960364 A ITRM960364 A IT RM960364A IT RM960364 A0 ITRM960364 A0 IT RM960364A0
- Authority
- IT
- Italy
- Prior art keywords
- treatment
- therapeutic agent
- degenerative diseases
- active therapeutic
- neuronal degenerative
- Prior art date
Links
- 230000003412 degenerative effect Effects 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 230000001537 neural effect Effects 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96RM000364A IT1290781B1 (it) | 1996-05-28 | 1996-05-28 | Agente attivo terapeutico per il trattamento di malattie degenerative neuronali. |
AU30468/97A AU3046897A (en) | 1996-05-28 | 1997-05-23 | Uridine-comprising therapeutic active agent for treatment of neurodegenerative disorders |
EP97925266A EP0914131A1 (en) | 1996-05-28 | 1997-05-23 | Uridine-comprising therapeutic active agent for treatment of neurodegenerative disorders |
BR9709379-3A BR9709379A (pt) | 1996-05-28 | 1997-05-23 | Uso de uridina, e, composição para o tratamento de distúrbios do sistema nervoso devido à degeneração seletiva de células neuroniais ou gliais em mamìferos. |
JP54197097A JP3725172B2 (ja) | 1996-05-28 | 1997-05-23 | ウリジンからなる神経変性疾患の処置に活性な治療剤 |
CA002255748A CA2255748C (en) | 1996-05-28 | 1997-05-23 | Uridine-comprising therapeutic active agent for treatment of neurodegenerative disorders |
PCT/IT1997/000117 WO1997045127A1 (en) | 1996-05-28 | 1997-05-23 | Uridine-comprising therapeutic active agent for treatment of neurodegenerative disorders |
HU0000124A HUP0000124A3 (en) | 1996-05-28 | 1997-05-23 | Uridine-comprising therapeutic active agent for treatment of neurodegenerative disorders |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96RM000364A IT1290781B1 (it) | 1996-05-28 | 1996-05-28 | Agente attivo terapeutico per il trattamento di malattie degenerative neuronali. |
US1854396P | 1996-05-29 | 1996-05-29 |
Publications (3)
Publication Number | Publication Date |
---|---|
ITRM960364A0 true ITRM960364A0 (it) | 1996-05-28 |
ITRM960364A1 ITRM960364A1 (it) | 1997-11-28 |
IT1290781B1 IT1290781B1 (it) | 1998-12-10 |
Family
ID=26332100
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT96RM000364A IT1290781B1 (it) | 1996-05-28 | 1996-05-28 | Agente attivo terapeutico per il trattamento di malattie degenerative neuronali. |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0914131A1 (it) |
AU (1) | AU3046897A (it) |
IT (1) | IT1290781B1 (it) |
WO (1) | WO1997045127A1 (it) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8143234B2 (en) | 1998-07-31 | 2012-03-27 | Massachusetts Institute Of Technology | Uridine administration improves phosphatide synthesis, synaptic transmission and cognitive function |
US20050203053A1 (en) * | 1999-07-30 | 2005-09-15 | Wurtman Richard J. | Uridine administration improves phosphatide synthesis, synaptic transmission and cogntive function |
US8314064B2 (en) * | 1998-07-31 | 2012-11-20 | Massachusetts Institute Of Technology | Uridine administration stimulates membrane production |
ATE446097T1 (de) * | 1998-07-31 | 2009-11-15 | Massachusetts Inst Technology | Verwendung von uridin in kombination mit cholin zur behandlung von gedächtnisstörungen |
US8518882B2 (en) * | 1998-07-31 | 2013-08-27 | Massachusetts Institute Of Technology | Methods and compositions for ameliorating or inhibiting decline in memory or intelligence or improving same |
US7915233B1 (en) | 1998-08-31 | 2011-03-29 | Wellstat Therapeutics Corporation | Compositions and methods for treatment of mitochondrial diseases |
US7807654B2 (en) | 1998-08-31 | 2010-10-05 | Wellstat Therapeutics Corporation | Compositions and methods for treatment of mitochondrial diseases |
US6472378B2 (en) | 1998-08-31 | 2002-10-29 | Pro-Neuron, Inc. | Compositions and methods for treatment of mitochondrial diseases |
PT1390378E (pt) * | 2001-04-30 | 2009-07-23 | Trommsdorff Arzneimittel | Ésteres de uridina farmaceuticamente activos |
US6767202B2 (en) | 2001-12-18 | 2004-07-27 | 3M Innovative Properties Company | Tooling with helical coils for structured surface articles |
WO2005112635A2 (en) * | 2004-05-13 | 2005-12-01 | Massachusetts Institute Of Technology | Uridine effects on dopamine release |
JP2008513453A (ja) * | 2004-09-15 | 2008-05-01 | マサチューセッツ インスティテュート オブ テクノロジー | ウリジンを含んだ組成物及びその使用方法 |
WO2007060886A1 (ja) | 2005-11-24 | 2007-05-31 | National University Corporation Hokkaido University | 神経変性疾患治療薬 |
BRPI0817387A2 (pt) | 2007-11-02 | 2015-09-08 | Massachusetts Inst Technology | métodos de conformidade de suplementação dietária de uridina e uso dos mesmos |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1178044B (it) * | 1984-10-09 | 1987-09-03 | Polifarma Spa | Agente attivo farmaceutico per il trattamento di patologie cerebrali a base di uridina |
IT1219667B (it) * | 1988-06-21 | 1990-05-24 | Polifarma Spa | Impiego di uridina nel trattamento farmacologico di disturbi dovuti ad alterato equilibrio dopaminergico |
IT1241984B (it) * | 1990-06-13 | 1994-02-02 | Polifarma Spa | Impiego di uridina nel trattamento farmacologico delle complicazioni periferiche del diabete |
JPH05304951A (ja) * | 1992-04-06 | 1993-11-19 | N T Sci:Kk | 初期胚及び胚性幹細胞の培養液 |
-
1996
- 1996-05-28 IT IT96RM000364A patent/IT1290781B1/it active IP Right Grant
-
1997
- 1997-05-23 EP EP97925266A patent/EP0914131A1/en not_active Ceased
- 1997-05-23 AU AU30468/97A patent/AU3046897A/en not_active Abandoned
- 1997-05-23 WO PCT/IT1997/000117 patent/WO1997045127A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0914131A1 (en) | 1999-05-12 |
AU3046897A (en) | 1998-01-05 |
WO1997045127A1 (en) | 1997-12-04 |
IT1290781B1 (it) | 1998-12-10 |
ITRM960364A1 (it) | 1997-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted |