ITRM20050416A1 - Derivati delle benzodiazepine e loro usi in campo medico. - Google Patents

Derivati delle benzodiazepine e loro usi in campo medico.

Info

Publication number
ITRM20050416A1
ITRM20050416A1 IT000416A ITRM20050416A ITRM20050416A1 IT RM20050416 A1 ITRM20050416 A1 IT RM20050416A1 IT 000416 A IT000416 A IT 000416A IT RM20050416 A ITRM20050416 A IT RM20050416A IT RM20050416 A1 ITRM20050416 A1 IT RM20050416A1
Authority
IT
Italy
Prior art keywords
sub
alkyl
alkynyl
alkenyl
alkoxy
Prior art date
Application number
IT000416A
Other languages
English (en)
Inventor
Elisabetta Abruzzese
Gianfranco Catalano
Martino Maria Gabriella De
Stefano Carla Di
Regina Giuseppe La
Gabriella Marfe
Romano Silvestri
Salimei Paola Sinibaldi
Original Assignee
Uni Degli Studi Di Roma Tor Vergata
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uni Degli Studi Di Roma Tor Vergata filed Critical Uni Degli Studi Di Roma Tor Vergata
Priority to IT000416A priority Critical patent/ITRM20050416A1/it
Priority to PCT/IT2006/000401 priority patent/WO2007015280A1/en
Priority to US11/997,689 priority patent/US20080249080A1/en
Priority to EP06756301A priority patent/EP1910383B1/en
Priority to DE602006009276T priority patent/DE602006009276D1/de
Priority to AT06756301T priority patent/ATE443065T1/de
Publication of ITRM20050416A1 publication Critical patent/ITRM20050416A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
IT000416A 2005-08-03 2005-08-03 Derivati delle benzodiazepine e loro usi in campo medico. ITRM20050416A1 (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT000416A ITRM20050416A1 (it) 2005-08-03 2005-08-03 Derivati delle benzodiazepine e loro usi in campo medico.
PCT/IT2006/000401 WO2007015280A1 (en) 2005-08-03 2006-05-26 Benzodiazepine derivatives and uses thereof in medical field
US11/997,689 US20080249080A1 (en) 2005-08-03 2006-05-26 Benzodiazepine Derivatives and Uses Thereof on Medical Field
EP06756301A EP1910383B1 (en) 2005-08-03 2006-05-26 Benzodiazepine derivatives and uses thereof in medical field
DE602006009276T DE602006009276D1 (de) 2005-08-03 2006-05-26 Benzodiazepinderivate und anwendungen davon auf dem medizinischen gebiet
AT06756301T ATE443065T1 (de) 2005-08-03 2006-05-26 Benzodiazepinderivate und anwendungen davon auf dem medizinischen gebiet

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000416A ITRM20050416A1 (it) 2005-08-03 2005-08-03 Derivati delle benzodiazepine e loro usi in campo medico.

Publications (1)

Publication Number Publication Date
ITRM20050416A1 true ITRM20050416A1 (it) 2007-02-04

Family

ID=36889076

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000416A ITRM20050416A1 (it) 2005-08-03 2005-08-03 Derivati delle benzodiazepine e loro usi in campo medico.

Country Status (6)

Country Link
US (1) US20080249080A1 (it)
EP (1) EP1910383B1 (it)
AT (1) ATE443065T1 (it)
DE (1) DE602006009276D1 (it)
IT (1) ITRM20050416A1 (it)
WO (1) WO2007015280A1 (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2683325C2 (ru) 2009-02-05 2019-03-28 Иммьюноджен, Инк. Новые производные бензодиазепина
ES2717657T3 (es) 2011-02-15 2019-06-24 Immunogen Inc Métodos para la preparación de conjugados
EP2887965A1 (en) 2012-08-22 2015-07-01 ImmunoGen, Inc. Cytotoxic benzodiazepine derivatives
EP3189057A1 (en) 2014-09-03 2017-07-12 ImmunoGen, Inc. Cytotoxic benzodiazepine derivatives
DK3189056T3 (da) 2014-09-03 2020-09-14 Immunogen Inc Cytotoksiske benzodiazepinderivater
WO2018195243A1 (en) 2017-04-20 2018-10-25 Immunogen, Inc. Cytotoxic benzodiazepine derivatives and conjugates thereof
JP2021508714A (ja) 2017-12-28 2021-03-11 イミュノジェン・インコーポレーテッド ベンゾジアゼピン誘導体
US20230094471A1 (en) 2019-03-29 2023-03-30 Immunogen, Inc. Cytotoxic bis-benzodiazepine derivatives and conjugates thereof with cell-binding agents for inhibiting abnormal cell growth or for treating proliferative diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156746A (en) * 1998-08-25 2000-12-05 Bristol-Myers Squibb Company 1,2,5-benzothiadiazepine-1,1-dioxides with n-2 imidazolylalkyl substituents

Also Published As

Publication number Publication date
DE602006009276D1 (de) 2009-10-29
US20080249080A1 (en) 2008-10-09
EP1910383B1 (en) 2009-09-16
ATE443065T1 (de) 2009-10-15
WO2007015280A8 (en) 2008-04-10
EP1910383A1 (en) 2008-04-16
WO2007015280A1 (en) 2007-02-08

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