ITRM20040241A1 - Camptotecine coniugate in posizione 20 con antagonisti delle integrine. - Google Patents
Camptotecine coniugate in posizione 20 con antagonisti delle integrine.Info
- Publication number
- ITRM20040241A1 ITRM20040241A1 IT000241A ITRM20040241A ITRM20040241A1 IT RM20040241 A1 ITRM20040241 A1 IT RM20040241A1 IT 000241 A IT000241 A IT 000241A IT RM20040241 A ITRM20040241 A IT RM20040241A IT RM20040241 A1 ITRM20040241 A1 IT RM20040241A1
- Authority
- IT
- Italy
- Prior art keywords
- camptotecine
- integrine
- antagonists
- conjugated
- integrine antagonists
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000241A ITRM20040241A1 (it) | 2004-05-13 | 2004-05-13 | Camptotecine coniugate in posizione 20 con antagonisti delle integrine. |
BRPI0511037-8A BRPI0511037A (pt) | 2004-05-13 | 2005-05-04 | derivados de camptotecinas conjugados na posição 20 com antagonistas de integrina |
EP05743015A EP1747019A2 (en) | 2004-05-13 | 2005-05-04 | Camptothecin derivatives conjugated in position 20 with integrin antagonists |
MXPA06012886A MXPA06012886A (es) | 2004-05-13 | 2005-05-04 | Derivados de camptotecina conjugados en posicion 20 con antagonistas de integrina. |
AU2005243834A AU2005243834A1 (en) | 2004-05-13 | 2005-05-04 | Camptothecin derivatives conjugated in position 20 with integrin antagonists |
CNA2005800152323A CN101010103A (zh) | 2004-05-13 | 2005-05-04 | 在20位与整联蛋白拮抗剂缀合的喜树碱衍生物 |
CA002562572A CA2562572A1 (en) | 2004-05-13 | 2005-05-04 | Camptothecin derivatives conjugated in position 20 with integrin antagonists |
US11/596,189 US20070232639A1 (en) | 2004-05-13 | 2005-05-04 | Camptothecin Derivatives Conjugated in Position 20 with Integrin Antagonists |
JP2007512735A JP2007537244A (ja) | 2004-05-13 | 2005-05-04 | 20位にてインテグリンアンタゴニストと接合したカンプトテシン誘導体 |
PCT/IT2005/000261 WO2005110487A2 (en) | 2004-05-13 | 2005-05-04 | Camptothecin derivatives conjugated in position 20 with integrin antagonists |
TW094114403A TW200538125A (en) | 2004-05-13 | 2005-05-04 | Camptothecin derivatives conjugated in position 20 with integrin antagonists |
ARP050101933A AR049275A1 (es) | 2004-05-13 | 2005-05-12 | Derivados de camptotecina conjugada en posicion 20 con antagonistas de la integrina |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000241A ITRM20040241A1 (it) | 2004-05-13 | 2004-05-13 | Camptotecine coniugate in posizione 20 con antagonisti delle integrine. |
Publications (1)
Publication Number | Publication Date |
---|---|
ITRM20040241A1 true ITRM20040241A1 (it) | 2004-08-13 |
Family
ID=35124307
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT000241A ITRM20040241A1 (it) | 2004-05-13 | 2004-05-13 | Camptotecine coniugate in posizione 20 con antagonisti delle integrine. |
Country Status (12)
Country | Link |
---|---|
US (1) | US20070232639A1 (it) |
EP (1) | EP1747019A2 (it) |
JP (1) | JP2007537244A (it) |
CN (1) | CN101010103A (it) |
AR (1) | AR049275A1 (it) |
AU (1) | AU2005243834A1 (it) |
BR (1) | BRPI0511037A (it) |
CA (1) | CA2562572A1 (it) |
IT (1) | ITRM20040241A1 (it) |
MX (1) | MXPA06012886A (it) |
TW (1) | TW200538125A (it) |
WO (1) | WO2005110487A2 (it) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008098788A2 (en) * | 2007-02-16 | 2008-08-21 | Ktb Tumorforschungsgesellschaft Mbh | Receptor and antigen targeted prodrug |
BR112014016736A8 (pt) * | 2012-01-27 | 2017-07-04 | Hoffmann La Roche | composto, composição farmacêutica, método para tratamento, uso de um composto e invenção |
CN105399757A (zh) * | 2015-12-29 | 2016-03-16 | 遵义医学院 | 酸敏感型喜树碱-20位去甲斑蝥酸酯衍生物及其抗肿瘤应用 |
CN111068068A (zh) * | 2019-12-04 | 2020-04-28 | 云南民族大学 | 一种rgd多肽-喜树碱多肽药物偶联物及其应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19815812A1 (de) * | 1998-04-08 | 1999-10-14 | Bayer Ag | Modifizierte Cytostatika |
PT1044977E (pt) * | 1999-03-09 | 2002-09-30 | Sigma Tau Ind Farmaceuti | Derivados de camptotecina com actividade antitumoral |
US6207832B1 (en) * | 1999-04-09 | 2001-03-27 | University Of Pittsburgh | Camptothecin analogs and methods of preparation thereof |
CA2383981A1 (en) * | 1999-09-08 | 2001-03-15 | Bayer Aktiengesellschaft | Integrin-mediated drug targeting |
-
2004
- 2004-05-13 IT IT000241A patent/ITRM20040241A1/it unknown
-
2005
- 2005-05-04 WO PCT/IT2005/000261 patent/WO2005110487A2/en active Application Filing
- 2005-05-04 BR BRPI0511037-8A patent/BRPI0511037A/pt not_active IP Right Cessation
- 2005-05-04 CA CA002562572A patent/CA2562572A1/en not_active Abandoned
- 2005-05-04 US US11/596,189 patent/US20070232639A1/en not_active Abandoned
- 2005-05-04 EP EP05743015A patent/EP1747019A2/en not_active Withdrawn
- 2005-05-04 AU AU2005243834A patent/AU2005243834A1/en not_active Abandoned
- 2005-05-04 JP JP2007512735A patent/JP2007537244A/ja not_active Withdrawn
- 2005-05-04 MX MXPA06012886A patent/MXPA06012886A/es not_active Application Discontinuation
- 2005-05-04 CN CNA2005800152323A patent/CN101010103A/zh active Pending
- 2005-05-04 TW TW094114403A patent/TW200538125A/zh unknown
- 2005-05-12 AR ARP050101933A patent/AR049275A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP1747019A2 (en) | 2007-01-31 |
JP2007537244A (ja) | 2007-12-20 |
MXPA06012886A (es) | 2007-02-15 |
CA2562572A1 (en) | 2005-11-24 |
US20070232639A1 (en) | 2007-10-04 |
AR049275A1 (es) | 2006-07-12 |
WO2005110487A3 (en) | 2007-02-15 |
TW200538125A (en) | 2005-12-01 |
AU2005243834A1 (en) | 2005-11-24 |
BRPI0511037A (pt) | 2007-11-27 |
WO2005110487A2 (en) | 2005-11-24 |
CN101010103A (zh) | 2007-08-01 |
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