ITMI20062208A1 - PROCESS FOR THE PREPARATION OF IMATINIB AND ITS INTERMEDIATES - Google Patents

PROCESS FOR THE PREPARATION OF IMATINIB AND ITS INTERMEDIATES

Info

Publication number
ITMI20062208A1
ITMI20062208A1 ITMI20062208A ITMI20062208A1 IT MI20062208 A1 ITMI20062208 A1 IT MI20062208A1 IT MI20062208 A ITMI20062208 A IT MI20062208A IT MI20062208 A1 ITMI20062208 A1 IT MI20062208A1
Authority
IT
Italy
Prior art keywords
imatinib
intermediates
preparation
Prior art date
Application number
Other languages
Italian (it)
Inventor
Riccardo Motterle
Mariano Stivanello
Original Assignee
F I S Fabbrica Italiana Sintetici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F I S Fabbrica Italiana Sintetici Spa filed Critical F I S Fabbrica Italiana Sintetici Spa
Priority to ITMI20062208 priority Critical patent/ITMI20062208A1/en
Priority to RU2009122692/04A priority patent/RU2480461C2/en
Priority to CN2007800392449A priority patent/CN101528700B/en
Priority to ES07849757.5T priority patent/ES2496592T3/en
Priority to JP2009536868A priority patent/JP5265562B2/en
Priority to US12/515,105 priority patent/US8168787B2/en
Priority to EP07849757.5A priority patent/EP2074095B1/en
Priority to KR1020097011914A priority patent/KR101420892B1/en
Priority to BRPI0718812-9A2A priority patent/BRPI0718812A2/en
Priority to PCT/IT2007/000804 priority patent/WO2008059551A2/en
Publication of ITMI20062208A1 publication Critical patent/ITMI20062208A1/en
Priority to IL197954A priority patent/IL197954A/en
Priority to US12/784,366 priority patent/US8334381B2/en

Links

ITMI20062208 2006-11-16 2006-11-16 PROCESS FOR THE PREPARATION OF IMATINIB AND ITS INTERMEDIATES ITMI20062208A1 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
ITMI20062208 ITMI20062208A1 (en) 2006-11-16 2006-11-16 PROCESS FOR THE PREPARATION OF IMATINIB AND ITS INTERMEDIATES
US12/515,105 US8168787B2 (en) 2006-11-16 2007-11-15 Process for the preparation of imatinib and intermediates thereof
CN2007800392449A CN101528700B (en) 2006-11-16 2007-11-15 Process for the preparation of imatinib and intermediates thereof
ES07849757.5T ES2496592T3 (en) 2006-11-16 2007-11-15 Process for the preparation of Imatinib and intermediate compounds thereof
JP2009536868A JP5265562B2 (en) 2006-11-16 2007-11-15 Process for the preparation of imatinib and its intermediates
RU2009122692/04A RU2480461C2 (en) 2006-11-16 2007-11-15 Method of producing imatinib and intermediate compounds thereof
EP07849757.5A EP2074095B1 (en) 2006-11-16 2007-11-15 Process for the preparation of imatinib and intermediates thereof
KR1020097011914A KR101420892B1 (en) 2006-11-16 2007-11-15 Process for the preparation of Imatinib and intermediates thereof
BRPI0718812-9A2A BRPI0718812A2 (en) 2006-11-16 2007-11-15 PROCESS FOR PREPARATION OF IMATINIB AND INTERMEDIARIES OF THIS
PCT/IT2007/000804 WO2008059551A2 (en) 2006-11-16 2007-11-15 Process for the preparation of imatinib and intermediates thereof
IL197954A IL197954A (en) 2006-11-16 2009-04-05 Process for the preparation of imatinib, intermediates thereof and process for preparing said intermediates
US12/784,366 US8334381B2 (en) 2006-11-16 2010-05-20 Process for the preparation of intermediates useful in the synthesis of imatinib

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI20062208 ITMI20062208A1 (en) 2006-11-16 2006-11-16 PROCESS FOR THE PREPARATION OF IMATINIB AND ITS INTERMEDIATES

Publications (1)

Publication Number Publication Date
ITMI20062208A1 true ITMI20062208A1 (en) 2008-05-17

Family

ID=40277989

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI20062208 ITMI20062208A1 (en) 2006-11-16 2006-11-16 PROCESS FOR THE PREPARATION OF IMATINIB AND ITS INTERMEDIATES

Country Status (2)

Country Link
CN (1) CN101528700B (en)
IT (1) ITMI20062208A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102372690B (en) * 2010-08-20 2014-05-28 成都地奥制药集团有限公司 Intermediate for synthesizing imatinib and application of intermediate in imatinib synthesis
CN103539639B (en) * 2010-11-09 2015-05-20 常州制药厂有限公司 Method for preparing key intermediate of medicament
CN102001920B (en) * 2010-11-09 2013-05-15 常州制药厂有限公司 Preparation method of medicine intermediate
CN102382100B (en) * 2011-03-09 2014-04-16 上海昕盛医药科技有限公司 Preparation method of imatinib
CN102617475A (en) * 2012-03-07 2012-08-01 南开大学 Method for decarboxylation of N-methyl-3-alkyl-4 -nitropyrazole formate
CN102796074B (en) * 2012-06-21 2015-04-08 苏州立新制药有限公司 Method for preparing imatinib mesylate intermediate
CN103694145B (en) * 2013-11-28 2016-02-10 山东鑫泉医药有限公司 The synthetic method of (2-methyl-5-nitrophenyl) guanidine sulfate
CN108148003B (en) * 2018-01-16 2021-03-26 棓诺(苏州)新材料有限公司 Method for synthesizing benzoylpyrimidine compound serving as intermediate of OLED (organic light emitting diode) material
CN109682914A (en) * 2019-01-16 2019-04-26 徐州立兴佳正医药科技有限公司 A kind of method that LC-MS measures Imatinib concentration in blood plasma

Also Published As

Publication number Publication date
CN101528700A (en) 2009-09-09
CN101528700B (en) 2012-05-30

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