ITMI20032069A1 - Procedimento per la preparazione di derivati benzilmidazolici. - Google Patents

Procedimento per la preparazione di derivati benzilmidazolici.

Info

Publication number
ITMI20032069A1
ITMI20032069A1 IT002069A ITMI20032069A ITMI20032069A1 IT MI20032069 A1 ITMI20032069 A1 IT MI20032069A1 IT 002069 A IT002069 A IT 002069A IT MI20032069 A ITMI20032069 A IT MI20032069A IT MI20032069 A1 ITMI20032069 A1 IT MI20032069A1
Authority
IT
Italy
Prior art keywords
benzylmidazolic
derivatives
procedure
preparation
benzylmidazolic derivatives
Prior art date
Application number
IT002069A
Other languages
English (en)
Inventor
Pietro Allegrini
Graziano Castaldi
Vittorio Lucchini
Gabriele Razzetti
Original Assignee
Dinamite Dipharma S P A In Forma A Bbreviata Diph
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dinamite Dipharma S P A In Forma A Bbreviata Diph filed Critical Dinamite Dipharma S P A In Forma A Bbreviata Diph
Priority to IT002069A priority Critical patent/ITMI20032069A1/it
Priority to EP04024761A priority patent/EP1548009A3/en
Priority to JP2004305424A priority patent/JP2005126434A/ja
Priority to US10/969,354 priority patent/US7164029B2/en
Publication of ITMI20032069A1 publication Critical patent/ITMI20032069A1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70One oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68Halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT002069A 2003-10-23 2003-10-23 Procedimento per la preparazione di derivati benzilmidazolici. ITMI20032069A1 (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT002069A ITMI20032069A1 (it) 2003-10-23 2003-10-23 Procedimento per la preparazione di derivati benzilmidazolici.
EP04024761A EP1548009A3 (en) 2003-10-23 2004-10-18 Process for the preparation of benzylimidazole derivatives and for losartan.
JP2004305424A JP2005126434A (ja) 2003-10-23 2004-10-20 ベンジルイミダゾール誘導体の製造方法
US10/969,354 US7164029B2 (en) 2003-10-23 2004-10-21 Process for the preparation of benzylimidazole derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002069A ITMI20032069A1 (it) 2003-10-23 2003-10-23 Procedimento per la preparazione di derivati benzilmidazolici.

Publications (1)

Publication Number Publication Date
ITMI20032069A1 true ITMI20032069A1 (it) 2005-04-24

Family

ID=34509457

Family Applications (1)

Application Number Title Priority Date Filing Date
IT002069A ITMI20032069A1 (it) 2003-10-23 2003-10-23 Procedimento per la preparazione di derivati benzilmidazolici.

Country Status (4)

Country Link
US (1) US7164029B2 (it)
EP (1) EP1548009A3 (it)
JP (1) JP2005126434A (it)
IT (1) ITMI20032069A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1741711A1 (en) * 2005-07-04 2007-01-10 KRKA, D.D., Novo Mesto A process for the preparation of losartan derivatives by chlorination and reduction of the respective 1H-imidazole-5-carbaldehydes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08500323A (ja) * 1991-11-18 1996-01-16 イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー A▲ii▼受容体アンタゴニストの合成のためのテトラゾリルフェニルボロン酸中間体
AU696868B2 (en) * 1994-03-29 1998-09-17 Merck & Co., Inc. Treatment of atherosclerosis with angiotensin II receptor blocking imidazoles
US6933294B2 (en) * 2002-04-03 2005-08-23 Bristol-Myers Squibb Company Thiophene-based tricyclic compounds and pharmaceutical compositions comprising same

Also Published As

Publication number Publication date
EP1548009A3 (en) 2005-11-16
EP1548009A2 (en) 2005-06-29
US20050090672A1 (en) 2005-04-28
JP2005126434A (ja) 2005-05-19
US7164029B2 (en) 2007-01-16

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