ITMI20030743A1 - POLYETHYLENGLYCULATED DERIVATIVES THAT RELEASE NITRIC OXIDE. - Google Patents

POLYETHYLENGLYCULATED DERIVATIVES THAT RELEASE NITRIC OXIDE.

Info

Publication number
ITMI20030743A1
ITMI20030743A1 IT000743A ITMI20030743A ITMI20030743A1 IT MI20030743 A1 ITMI20030743 A1 IT MI20030743A1 IT 000743 A IT000743 A IT 000743A IT MI20030743 A ITMI20030743 A IT MI20030743A IT MI20030743 A1 ITMI20030743 A1 IT MI20030743A1
Authority
IT
Italy
Prior art keywords
polyethylenglyculated
derivatives
nitric oxide
release nitric
release
Prior art date
Application number
IT000743A
Other languages
Italian (it)
Inventor
Gianfranco Pasut
Francesco Maria Veronese
Original Assignee
Biopeg Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biopeg Ltd filed Critical Biopeg Ltd
Priority to IT000743A priority Critical patent/ITMI20030743A1/en
Priority to PCT/IB2004/001080 priority patent/WO2004089420A1/en
Publication of ITMI20030743A1 publication Critical patent/ITMI20030743A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
IT000743A 2003-04-11 2003-04-11 POLYETHYLENGLYCULATED DERIVATIVES THAT RELEASE NITRIC OXIDE. ITMI20030743A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT000743A ITMI20030743A1 (en) 2003-04-11 2003-04-11 POLYETHYLENGLYCULATED DERIVATIVES THAT RELEASE NITRIC OXIDE.
PCT/IB2004/001080 WO2004089420A1 (en) 2003-04-11 2004-04-06 Polyethylene glycol conjugates releasing nitric oxide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000743A ITMI20030743A1 (en) 2003-04-11 2003-04-11 POLYETHYLENGLYCULATED DERIVATIVES THAT RELEASE NITRIC OXIDE.

Publications (1)

Publication Number Publication Date
ITMI20030743A1 true ITMI20030743A1 (en) 2004-10-12

Family

ID=33156344

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000743A ITMI20030743A1 (en) 2003-04-11 2003-04-11 POLYETHYLENGLYCULATED DERIVATIVES THAT RELEASE NITRIC OXIDE.

Country Status (2)

Country Link
IT (1) ITMI20030743A1 (en)
WO (1) WO2004089420A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7691364B2 (en) 2005-01-28 2010-04-06 Bezwada Biomedical, Llc Functionalized drugs and polymers derived therefrom
US7858077B2 (en) * 2005-01-28 2010-12-28 Bezwada Biomedical Llc Functionalized phenolic esters and amides and polymers therefrom
US8728493B2 (en) 2005-06-17 2014-05-20 Nektar Therapeutics Polymer based compositions and conjugates of non-steroidal anti-inflammatory drugs
US9283279B2 (en) 2011-05-11 2016-03-15 Ramot At Tel-Aviv University Ltd. Targeted polymeric conjugates and uses thereof
CA2843506C (en) * 2011-08-12 2020-05-12 Ascendis Pharma A/S Carrier-linked prodrugs having reversible carboxylic ester linkages
CN111514309B (en) * 2019-02-03 2021-09-17 重庆阿普格雷生物科技有限公司 Polyethylene glycol coupled drug, preparation method and application thereof
CN112707947B (en) * 2020-12-29 2022-06-17 湖南华腾制药有限公司 Adriamycin prodrug, preparation method and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3703900A (en) * 1999-02-24 2000-09-14 Nitromed, Inc. Nitrosated and nitrosylated steroids for the treatment of cardiovascular diseases and disorders
CA2410632A1 (en) * 2000-06-22 2001-12-27 David S. Garvey Nitrosated and nitrosylated taxanes, compositions and methods of use
US6780849B2 (en) * 2000-12-21 2004-08-24 Scimed Life Systems, Inc. Lipid-based nitric oxide donors
EP1219306A1 (en) * 2000-12-29 2002-07-03 Nicox S.A. Compositions comprising cyclodextrins and NO- releasing drugs
AU2003278565A1 (en) * 2002-10-25 2004-05-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments

Also Published As

Publication number Publication date
WO2004089420A1 (en) 2004-10-21

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