ITMI20030312A1 - Derivati di acidi 2-fenil-2-alchil-acetici per il trattamento della malattia di alzheimer. - Google Patents
Derivati di acidi 2-fenil-2-alchil-acetici per il trattamento della malattia di alzheimer.Info
- Publication number
- ITMI20030312A1 ITMI20030312A1 IT000312A ITMI20030312A ITMI20030312A1 IT MI20030312 A1 ITMI20030312 A1 IT MI20030312A1 IT 000312 A IT000312 A IT 000312A IT MI20030312 A ITMI20030312 A IT MI20030312A IT MI20030312 A1 ITMI20030312 A1 IT MI20030312A1
- Authority
- IT
- Italy
- Prior art keywords
- alchyl
- fenyl
- derivatives
- treatment
- alzheimer disease
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000312A ITMI20030312A1 (it) | 2003-02-21 | 2003-02-21 | Derivati di acidi 2-fenil-2-alchil-acetici per il trattamento della malattia di alzheimer. |
PCT/EP2004/001595 WO2004073705A1 (en) | 2003-02-21 | 2004-02-19 | 1-phenyl-2- monoalkyl carboxylic acid derivatives for the treatment of neurodegenerative diseases |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000312A ITMI20030312A1 (it) | 2003-02-21 | 2003-02-21 | Derivati di acidi 2-fenil-2-alchil-acetici per il trattamento della malattia di alzheimer. |
Publications (1)
Publication Number | Publication Date |
---|---|
ITMI20030312A1 true ITMI20030312A1 (it) | 2004-08-22 |
Family
ID=32894162
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT000312A ITMI20030312A1 (it) | 2003-02-21 | 2003-02-21 | Derivati di acidi 2-fenil-2-alchil-acetici per il trattamento della malattia di alzheimer. |
Country Status (2)
Country | Link |
---|---|
IT (1) | ITMI20030312A1 (it) |
WO (1) | WO2004073705A1 (it) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1604970A1 (en) * | 2004-05-19 | 2005-12-14 | Cellzome Ag | 2-(Biphenyl-3-yl)-carboxylic acids of gamma-secretase-modulating activity |
WO2005110963A1 (en) * | 2004-05-19 | 2005-11-24 | Cellzome Ag | (biphenyl-3-yl)-carboxylic acids and derivatives thereof and their use in therapy |
EP1650183A1 (en) * | 2004-10-21 | 2006-04-26 | Cellzome Ag | (Benzyloxy-biphenyl) acetic acids and derivatives thereof and their use in therapy |
US20110040094A1 (en) * | 2007-09-14 | 2011-02-17 | Envivo Pharmaceuticals, Inc. | 1,3,4-trisubstituted benzenes |
CN102272133A (zh) | 2008-11-06 | 2011-12-07 | 阿斯利康(瑞典)有限公司 | 淀粉样β的调节剂 |
CA2796933A1 (en) | 2010-04-21 | 2011-10-27 | Chiesi Farmaceutici S.P.A. | 1-(2-fluorobiphenyl-4-yl)-alkyl carboxylic acid derivatives for the therapy of transthyretin amyloidosis |
JP6368777B2 (ja) | 2013-06-04 | 2018-08-01 | アクチュラム・ライフ・サイエンス・アクチエボラーグ | ピリミジン化合物およびガンマセクレターゼモジュレーターとしてのその使用 |
EP3004080B1 (en) | 2013-06-04 | 2018-10-10 | Acturum Real Estate AB | Triazole compounds and their use as gamma secretase modulators |
WO2014195321A1 (en) | 2013-06-04 | 2014-12-11 | Acturum Life Science AB | Triazole compounds and their use as gamma secretase modulators |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5994379A (en) * | 1998-02-13 | 1999-11-30 | Merck Frosst Canada, Inc. | Bisaryl COX-2 inhibiting compounds, compositions and methods of use |
DE19907895A1 (de) * | 1999-02-24 | 2000-11-16 | Paz Arzneimittelentwicklung | Verwendung von R-Arylpropionsäuren zur Herstellung von Arzneimitteln zur Behandlung von Erkrankungen bei Mensch und Tier, welche durch die Hemmung der Aktivierung von NF-kB therapeutisch beeinflußt werden können |
JP2003530437A (ja) * | 2000-04-13 | 2003-10-14 | マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ | Aβ42低下物質 |
-
2003
- 2003-02-21 IT IT000312A patent/ITMI20030312A1/it unknown
-
2004
- 2004-02-19 WO PCT/EP2004/001595 patent/WO2004073705A1/en active Search and Examination
Also Published As
Publication number | Publication date |
---|---|
WO2004073705A1 (en) | 2004-09-02 |
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