IT8223770A0 - Composto ad attivita'vasodilatatrice, antiaggregante e ipocolesterolemizzante, procedimento per la sua preparazione e composizione farmaceutiche relative. - Google Patents
Composto ad attivita'vasodilatatrice, antiaggregante e ipocolesterolemizzante, procedimento per la sua preparazione e composizione farmaceutiche relative.Info
- Publication number
- IT8223770A0 IT8223770A0 IT8223770A IT2377082A IT8223770A0 IT 8223770 A0 IT8223770 A0 IT 8223770A0 IT 8223770 A IT8223770 A IT 8223770A IT 2377082 A IT2377082 A IT 2377082A IT 8223770 A0 IT8223770 A0 IT 8223770A0
- Authority
- IT
- Italy
- Prior art keywords
- hypocholesteromizing
- vasodilator
- aggregation
- activity
- procedure
- Prior art date
Links
- 230000002744 anti-aggregatory effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229940124549 vasodilator Drugs 0.000 title 1
- 239000003071 vasodilator agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/28—Two oxygen or sulfur atoms
- C07D231/30—Two oxygen or sulfur atoms attached in positions 3 and 5
- C07D231/32—Oxygen atoms
- C07D231/36—Oxygen atoms with hydrocarbon radicals, substituted by hetero atoms, attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT23770/82A IT1191034B (it) | 1982-10-15 | 1982-10-15 | Composto ad attivita' vasodilatatrice,antiaggregante e ipocolesterolemizzante,procedimento per la sua preparazione e composizione farmaceutiche relative |
DE8383109845T DE3369136D1 (en) | 1982-10-15 | 1983-10-02 | Pyrazolidinedione derivative having vasodilating, antiaggregating and hypocholesterolemic activities |
AT83109845T ATE24906T1 (de) | 1982-10-15 | 1983-10-02 | Pyrazolidinedion-derivate mit gefaesserweiternder, antiaggregationer und hypocholesterolemischer wirkung. |
EP83109845A EP0106251B1 (en) | 1982-10-15 | 1983-10-02 | Pyrazolidinedione derivative having vasodilating, antiaggregating and hypocholesterolemic activities |
US06/539,839 US4542141A (en) | 1982-10-15 | 1983-10-07 | Compound having vasodilating, antiaggregating and hypocholesterolemic activities, process for the preparation thereof and pharmaceutical compositions therefrom |
JP58193326A JPS5998082A (ja) | 1982-10-15 | 1983-10-14 | 1,2―ジフェニル―4―〔2―(フェニルスルフィニル)エチル〕―4―(ニコチノイルオキシメチル)―ピラゾリジン―3,5―ジオン、その製造法およびそれを有効成分とする血栓治療剤 |
ES526461A ES8507538A1 (es) | 1982-10-15 | 1983-10-14 | Procedimiento para la preparacion del 1,2-difenil-4-(2-(fenilsulfinil)-etil)-4-(nicotinoiloximetil)-pirazolidin-3,5-diona |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT23770/82A IT1191034B (it) | 1982-10-15 | 1982-10-15 | Composto ad attivita' vasodilatatrice,antiaggregante e ipocolesterolemizzante,procedimento per la sua preparazione e composizione farmaceutiche relative |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8223770A0 true IT8223770A0 (it) | 1982-10-15 |
IT1191034B IT1191034B (it) | 1988-02-24 |
Family
ID=11209829
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT23770/82A IT1191034B (it) | 1982-10-15 | 1982-10-15 | Composto ad attivita' vasodilatatrice,antiaggregante e ipocolesterolemizzante,procedimento per la sua preparazione e composizione farmaceutiche relative |
Country Status (7)
Country | Link |
---|---|
US (1) | US4542141A (it) |
EP (1) | EP0106251B1 (it) |
JP (1) | JPS5998082A (it) |
AT (1) | ATE24906T1 (it) |
DE (1) | DE3369136D1 (it) |
ES (1) | ES8507538A1 (it) |
IT (1) | IT1191034B (it) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5008257A (en) * | 1982-05-18 | 1991-04-16 | University Of Florida | Brain-specific drug delivery |
US5525727A (en) * | 1982-05-18 | 1996-06-11 | University Of Florida | Brain-specific drug delivery |
US4824850A (en) * | 1982-05-18 | 1989-04-25 | University Of Florida | Brain-specific drug delivery |
US5187158A (en) * | 1982-05-18 | 1993-02-16 | University Of Florida | Brain-specific drug delivery |
US5506193A (en) * | 1991-03-19 | 1996-04-09 | Ciba-Geigy Corporation | Herbicidally, acaricidally and insecticidally active pyrazolidine compounds |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL89284C (it) * | 1954-05-22 | |||
GB1084247A (it) * | 1963-08-20 | |||
BR6685653D0 (pt) * | 1965-12-23 | 1973-12-27 | Spofa Vereinigte Pharma Werke | Processo para a fabricacao de novas 4-substituidas 1,2-difenil-3,5-dioxopirazolidinas |
ES347942A1 (es) * | 1967-11-23 | 1969-03-01 | Esteve Labor Dr | Procedimiento para la obtencion de nuevos esteres de acidosp-halogenobenzoicos. |
AT324331B (de) * | 1972-09-27 | 1975-08-25 | Hurka Wilhelm | Verfahren zur herstellung neuer nicotin- und isonicotinsäureester substituierter pyrazolidine |
FR2433020A1 (fr) * | 1978-08-09 | 1980-03-07 | Synthelabo | Derives de pyrazolidine-dione et leur application en therapeutique |
-
1982
- 1982-10-15 IT IT23770/82A patent/IT1191034B/it active
-
1983
- 1983-10-02 DE DE8383109845T patent/DE3369136D1/de not_active Expired
- 1983-10-02 EP EP83109845A patent/EP0106251B1/en not_active Expired
- 1983-10-02 AT AT83109845T patent/ATE24906T1/de not_active IP Right Cessation
- 1983-10-07 US US06/539,839 patent/US4542141A/en not_active Expired - Fee Related
- 1983-10-14 JP JP58193326A patent/JPS5998082A/ja active Granted
- 1983-10-14 ES ES526461A patent/ES8507538A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES526461A0 (es) | 1985-10-01 |
DE3369136D1 (en) | 1987-02-19 |
JPS5998082A (ja) | 1984-06-06 |
IT1191034B (it) | 1988-02-24 |
JPS6346076B2 (it) | 1988-09-13 |
EP0106251A1 (en) | 1984-04-25 |
EP0106251B1 (en) | 1987-01-14 |
ES8507538A1 (es) | 1985-10-01 |
US4542141A (en) | 1985-09-17 |
ATE24906T1 (de) | 1987-01-15 |
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