IT8220356A0 - Guanidino eterociclifenilamidine, processi per la loro preparazione e loro impiego farmaceutico. - Google Patents
Guanidino eterociclifenilamidine, processi per la loro preparazione e loro impiego farmaceutico.Info
- Publication number
- IT8220356A0 IT8220356A0 IT8220356A IT2035682A IT8220356A0 IT 8220356 A0 IT8220356 A0 IT 8220356A0 IT 8220356 A IT8220356 A IT 8220356A IT 2035682 A IT2035682 A IT 2035682A IT 8220356 A0 IT8220356 A0 IT 8220356A0
- Authority
- IT
- Italy
- Prior art keywords
- heterocycliphenylamidines
- guanidino
- processes
- preparation
- pharmaceutical use
- Prior art date
Links
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical class NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/535—Organo-phosphoranes
- C07F9/5355—Phosphoranes containing the structure P=N-
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5463—Compounds of the type "quasi-phosphonium", e.g. (C)a-P-(Y)b wherein a+b=4, b>=1 and Y=heteroatom, generally N or O
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Cosmetics (AREA)
Priority Applications (32)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20356/82A IT1200371B (it) | 1982-03-24 | 1982-03-24 | Guanidino eterociclifenilamidine,processi per la loro preparazione e loro impiego farmaceutico |
US06/465,572 US4548944A (en) | 1982-03-24 | 1983-02-10 | Guanidino-heterocyclyl-phenyl-amidines and salts thereof |
DK63183A DK63183A (da) | 1982-03-24 | 1983-02-14 | Fremgangsmaade til fremstilling af guanidino-heterocycliske phenylamidiner og syreadditionssalte deraf |
PH28544A PH20677A (en) | 1982-03-24 | 1983-02-21 | Guanidino-heterocyclyl-phenyl-amidines and salts thereof |
DE198383200388T DE89730T1 (de) | 1982-03-24 | 1983-03-22 | Heterocyclische guanidino-phenylamidine, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung. |
KR1019830001151A KR840004089A (ko) | 1982-03-24 | 1983-03-22 | 구아니디노 헤테로사이클릭페닐아미딘의 제조방법 |
FI830940A FI78476C (fi) | 1982-03-24 | 1983-03-22 | Foerfarande foer framstaellning av farmakologiskt anvaendbara guanidino-heterocyklo-fenylamidiner. |
AT83200388T ATE27455T1 (de) | 1982-03-24 | 1983-03-22 | Heterocyclische guanidino-phenylamidine, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung. |
YU689/83A YU43160B (en) | 1982-03-24 | 1983-03-22 | Process for making guanidino heterocycliphenyl-amidins |
DE8383200388T DE3371784D1 (en) | 1982-03-24 | 1983-03-22 | Guanidino heterocyclicphenylamidines, processes for their preparation and their pharmaceutical use |
EP83200388A EP0089730B1 (en) | 1982-03-24 | 1983-03-22 | Guanidino heterocyclicphenylamidines, processes for their preparation and their pharmaceutical use |
DD83249053A DD232704A5 (de) | 1982-03-24 | 1983-03-22 | Verfahren zur herstellung von heterocyclischen guanidinphenylamidinen |
GR70860A GR77435B (it) | 1982-03-24 | 1983-03-23 | |
NO831027A NO159269C (no) | 1982-03-24 | 1983-03-23 | Analogifremgangsmaate for fremstilling av terapeutisk aktive heterocykliske fenylamidiner. |
ES520868A ES8404981A1 (es) | 1982-03-24 | 1983-03-23 | Un procedimiento para preparar guanidino-fenilamidinas heterociclicas sustituidas. |
SU833566497A SU1151208A3 (ru) | 1982-03-24 | 1983-03-23 | Способ получени производных гетероциклсодержащего фениламидина или их кислотно-аддитивных солей |
GB08307957A GB2116975B (en) | 1982-03-24 | 1983-03-23 | Guanidines |
HU83976A HU187877B (en) | 1982-03-24 | 1983-03-23 | Process for preparing guanidino-heterocyclyl-phenyl-amidines and pharmaceutical compositions containing thereof |
NZ203663A NZ203663A (en) | 1982-03-24 | 1983-03-23 | Heterocyclic compounds and pharmaceutical compositions |
CA000424307A CA1190546A (en) | 1982-03-24 | 1983-03-23 | Guanidino heterocyclicphenylamidines, processes for their preparation and their pharmaceutical use |
ZA832016A ZA832016B (en) | 1982-03-24 | 1983-03-23 | Guanidino heterocyclicphenylamidines,processes for their preparation and their pharmaceutical use |
IL68204A IL68204A (en) | 1982-03-24 | 1983-03-23 | Guanidinoazolylphenylamidine derivatives,their preparation and pharmaceutical compositions containing them |
JP58048611A JPS58185574A (ja) | 1982-03-24 | 1983-03-23 | 置換グアニジノ複素環式フエニルアミジン化合物 |
PT76432A PT76432B (en) | 1982-03-24 | 1983-03-23 | Guanidino heterocyclicphenylamidines processes for their preparation and their pharmaceutical use |
PL1983246384A PL139031B1 (en) | 1982-03-24 | 1983-03-23 | Method of obtaining new substituted quanidinoheterocyclophenyloamidines |
PL1983241145A PL138921B1 (en) | 1982-03-24 | 1983-03-23 | Process for preparing novel,substituted guanidineheterocyclophenylamidines |
ES520867A ES520867A0 (es) | 1982-03-24 | 1983-03-23 | Un procedimiento para preparar guanidino-fenilamidinas heterociclicas sustituidas. |
ES520869A ES8404982A1 (es) | 1982-03-24 | 1983-03-23 | Un procedimiento para preparar guanidino-fenilamidinas heterociclicas sustituidas. |
AU12732/83A AU562246B2 (en) | 1982-03-24 | 1983-03-23 | Hetero substituted phenyl formamidines |
SU833675010A SU1251804A3 (ru) | 1982-03-24 | 1983-12-05 | Способ получени производных гетероциклсодержащего фениламидина или их кислотно-аддитивных солей |
US06/748,309 US4645841A (en) | 1982-03-24 | 1985-06-24 | Guanidino-heterocyclyl-phenyl-amidines and salts thereof |
YU1521/85A YU43418B (en) | 1982-03-24 | 1985-09-24 | Process for making guanidino heterocycliphenyl-amidins |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20356/82A IT1200371B (it) | 1982-03-24 | 1982-03-24 | Guanidino eterociclifenilamidine,processi per la loro preparazione e loro impiego farmaceutico |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8220356A0 true IT8220356A0 (it) | 1982-03-24 |
IT1200371B IT1200371B (it) | 1989-01-18 |
Family
ID=11165991
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT20356/82A IT1200371B (it) | 1982-03-24 | 1982-03-24 | Guanidino eterociclifenilamidine,processi per la loro preparazione e loro impiego farmaceutico |
Country Status (24)
Country | Link |
---|---|
US (2) | US4548944A (it) |
EP (1) | EP0089730B1 (it) |
JP (1) | JPS58185574A (it) |
KR (1) | KR840004089A (it) |
AT (1) | ATE27455T1 (it) |
AU (1) | AU562246B2 (it) |
CA (1) | CA1190546A (it) |
DD (1) | DD232704A5 (it) |
DE (2) | DE89730T1 (it) |
DK (1) | DK63183A (it) |
ES (3) | ES8404982A1 (it) |
FI (1) | FI78476C (it) |
GB (1) | GB2116975B (it) |
GR (1) | GR77435B (it) |
HU (1) | HU187877B (it) |
IL (1) | IL68204A (it) |
IT (1) | IT1200371B (it) |
NO (1) | NO159269C (it) |
NZ (1) | NZ203663A (it) |
PL (2) | PL139031B1 (it) |
PT (1) | PT76432B (it) |
SU (2) | SU1151208A3 (it) |
YU (2) | YU43160B (it) |
ZA (1) | ZA832016B (it) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1210914B (it) * | 1982-07-29 | 1989-09-29 | Angeli Inst Spa | Eterociclilfenilsolfonil e fosfonilamidine sostituite, procedimento per la loro preparazione e loro uso farmaceutico. |
GB9125970D0 (en) * | 1991-12-06 | 1992-02-05 | Fujisawa Pharmaceutical Co | New compounds |
GB9211163D0 (en) * | 1992-05-26 | 1992-07-08 | Fujisawa Pharmaceutical Co | New oxazole derivatives |
US6787490B2 (en) * | 2001-12-26 | 2004-09-07 | Kimberly-Clark Worldwide, Inc. | Glove donning delivery system |
KR100969686B1 (ko) | 2006-08-07 | 2010-07-14 | 한국과학기술연구원 | 신규한 티아졸계 화합물 및 이를 함유하는 t-형 칼슘 채널저해제 |
US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2961923D1 (en) * | 1978-01-18 | 1982-03-11 | Ici Plc | Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them |
EP0014057B1 (en) * | 1979-01-18 | 1985-01-02 | Imperial Chemical Industries Plc | Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them |
IT1209431B (it) * | 1980-11-28 | 1989-07-16 | Angeli Inst Spa | Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione. |
-
1982
- 1982-03-24 IT IT20356/82A patent/IT1200371B/it active
-
1983
- 1983-02-10 US US06/465,572 patent/US4548944A/en not_active Expired - Fee Related
- 1983-02-14 DK DK63183A patent/DK63183A/da not_active Application Discontinuation
- 1983-03-22 DE DE198383200388T patent/DE89730T1/de active Pending
- 1983-03-22 DE DE8383200388T patent/DE3371784D1/de not_active Expired
- 1983-03-22 FI FI830940A patent/FI78476C/fi not_active IP Right Cessation
- 1983-03-22 EP EP83200388A patent/EP0089730B1/en not_active Expired
- 1983-03-22 DD DD83249053A patent/DD232704A5/de not_active IP Right Cessation
- 1983-03-22 AT AT83200388T patent/ATE27455T1/de not_active IP Right Cessation
- 1983-03-22 KR KR1019830001151A patent/KR840004089A/ko not_active Application Discontinuation
- 1983-03-22 YU YU689/83A patent/YU43160B/xx unknown
- 1983-03-23 ZA ZA832016A patent/ZA832016B/xx unknown
- 1983-03-23 JP JP58048611A patent/JPS58185574A/ja active Pending
- 1983-03-23 ES ES520869A patent/ES8404982A1/es not_active Expired
- 1983-03-23 PL PL1983246384A patent/PL139031B1/pl unknown
- 1983-03-23 IL IL68204A patent/IL68204A/xx unknown
- 1983-03-23 ES ES520868A patent/ES8404981A1/es not_active Expired
- 1983-03-23 HU HU83976A patent/HU187877B/hu not_active IP Right Cessation
- 1983-03-23 SU SU833566497A patent/SU1151208A3/ru active
- 1983-03-23 PL PL1983241145A patent/PL138921B1/pl unknown
- 1983-03-23 ES ES520867A patent/ES520867A0/es active Granted
- 1983-03-23 PT PT76432A patent/PT76432B/pt unknown
- 1983-03-23 CA CA000424307A patent/CA1190546A/en not_active Expired
- 1983-03-23 NO NO831027A patent/NO159269C/no unknown
- 1983-03-23 AU AU12732/83A patent/AU562246B2/en not_active Ceased
- 1983-03-23 NZ NZ203663A patent/NZ203663A/en unknown
- 1983-03-23 GB GB08307957A patent/GB2116975B/en not_active Expired
- 1983-03-23 GR GR70860A patent/GR77435B/el unknown
- 1983-12-05 SU SU833675010A patent/SU1251804A3/ru active
-
1985
- 1985-06-24 US US06/748,309 patent/US4645841A/en not_active Expired - Fee Related
- 1985-09-24 YU YU1521/85A patent/YU43418B/xx unknown
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