IT7951025A0 - Composti chinazolinici dotati di attivita cardiovascolare e procedimento per la loro preparazione - Google Patents

Composti chinazolinici dotati di attivita cardiovascolare e procedimento per la loro preparazione

Info

Publication number
IT7951025A0
IT7951025A0 IT7951025A IT5102579A IT7951025A0 IT 7951025 A0 IT7951025 A0 IT 7951025A0 IT 7951025 A IT7951025 A IT 7951025A IT 5102579 A IT5102579 A IT 5102579A IT 7951025 A0 IT7951025 A0 IT 7951025A0
Authority
IT
Italy
Prior art keywords
procedure
preparation
quinazoline compounds
cardiovascular activity
compounds equipped
Prior art date
Application number
IT7951025A
Other languages
English (en)
Other versions
IT1164812B (it
Inventor
Victor Bandurco
Seymour Levine
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of IT7951025A0 publication Critical patent/IT7951025A0/it
Application granted granted Critical
Publication of IT1164812B publication Critical patent/IT1164812B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/78Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/80Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827X being H
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT51025/79A 1978-12-07 1979-12-07 Composti chinazolinici dotati di attivita cardiovascolare e procedimento per la loro preparazione IT1164812B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96717378A 1978-12-07 1978-12-07
US6836779A 1979-08-21 1979-08-21

Publications (2)

Publication Number Publication Date
IT7951025A0 true IT7951025A0 (it) 1979-12-07
IT1164812B IT1164812B (it) 1987-04-15

Family

ID=26748897

Family Applications (1)

Application Number Title Priority Date Filing Date
IT51025/79A IT1164812B (it) 1978-12-07 1979-12-07 Composti chinazolinici dotati di attivita cardiovascolare e procedimento per la loro preparazione

Country Status (15)

Country Link
AT (1) AT374468B (it)
AU (1) AU533427B2 (it)
CA (1) CA1138871A (it)
CH (1) CH645106A5 (it)
DE (1) DE2949395A1 (it)
ES (1) ES8104253A1 (it)
FR (1) FR2443462A1 (it)
GB (1) GB2088874B (it)
IE (1) IE49469B1 (it)
IL (1) IL58898A (it)
IT (1) IT1164812B (it)
NL (1) NL7908849A (it)
PH (1) PH16910A (it)
PT (1) PT70559A (it)
SE (1) SE446181B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4631283A (en) * 1982-09-30 1986-12-23 Ortho Pharmaceutical Corporation Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids
US4490374A (en) * 1982-09-30 1984-12-25 Ortho Pharmaceutical Corporation 5,6-Dialkoxy-3,4-optionally substituted-2(1H)quinazolinones, composition and method of use
US4751304A (en) * 1984-09-26 1988-06-14 Ortho Pharmaceutical Corporation Process for preparing 5,6-dialkoxy-4-alkyl-2(1H)-quinazolinones
GB0015228D0 (en) * 2000-06-21 2000-08-16 Portela & Ca Sa Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders
USD966133S1 (en) * 2020-09-21 2022-10-11 Aileen Martin Sanitizer dispenser

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2118315C3 (de) * 1970-04-20 1975-04-03 Sumitomo Chemical Co., Ltd., Osaka (Japan) 2-(1H)-Chinazolinonderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US4129653A (en) * 1977-01-05 1978-12-12 Ortho Pharmaceutical Corporation Substituted pyrrolo [1,2-c] quinazolines and pharmaceutical compositions and methods employing them

Also Published As

Publication number Publication date
ES486696A0 (es) 1981-04-16
ES8104253A1 (es) 1981-04-16
AU533427B2 (en) 1983-11-24
IE792364L (en) 1980-06-07
GB2088874B (en) 1983-09-28
IE49469B1 (en) 1985-10-16
PT70559A (en) 1980-01-01
GB2088874A (en) 1982-06-16
IL58898A (en) 1984-03-30
DE2949395A1 (de) 1980-06-19
PH16910A (en) 1984-04-10
NL7908849A (nl) 1980-06-10
IT1164812B (it) 1987-04-15
CA1138871A (en) 1983-01-04
FR2443462B1 (it) 1983-09-23
SE7910105L (sv) 1980-06-08
SE446181B (sv) 1986-08-18
CH645106A5 (de) 1984-09-14
IL58898A0 (en) 1980-03-31
AU5347079A (en) 1980-06-12
ATA776379A (de) 1983-09-15
FR2443462A1 (fr) 1980-07-04
AT374468B (de) 1984-04-25

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