IT202000004123A1 - COMPOSITION FOR USE IN THERAPY, ESPECIALLY FOR THE TREATMENT OF DEPRESSION - Google Patents
COMPOSITION FOR USE IN THERAPY, ESPECIALLY FOR THE TREATMENT OF DEPRESSION Download PDFInfo
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- IT202000004123A1 IT202000004123A1 IT102020000004123A IT202000004123A IT202000004123A1 IT 202000004123 A1 IT202000004123 A1 IT 202000004123A1 IT 102020000004123 A IT102020000004123 A IT 102020000004123A IT 202000004123 A IT202000004123 A IT 202000004123A IT 202000004123 A1 IT202000004123 A1 IT 202000004123A1
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- 239000000203 mixture Substances 0.000 title claims description 28
- 238000002560 therapeutic procedure Methods 0.000 title claims description 6
- 208000020401 Depressive disease Diseases 0.000 title description 5
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 13
- 235000017309 Hypericum perforatum Nutrition 0.000 claims description 11
- 241000234435 Lilium Species 0.000 claims description 11
- 240000007673 Origanum vulgare Species 0.000 claims description 11
- 235000018185 Betula X alpestris Nutrition 0.000 claims description 10
- 235000018212 Betula X uliginosa Nutrition 0.000 claims description 10
- 241000201295 Euphrasia Species 0.000 claims description 10
- 235000013628 Lantana involucrata Nutrition 0.000 claims description 10
- 235000006677 Monarda citriodora ssp. austromontana Nutrition 0.000 claims description 10
- 241000219061 Rheum Species 0.000 claims description 10
- 235000009411 Rheum rhabarbarum Nutrition 0.000 claims description 10
- 239000002775 capsule Substances 0.000 claims description 9
- 241000546188 Hypericum Species 0.000 claims description 8
- 208000019901 Anxiety disease Diseases 0.000 claims description 5
- 230000036506 anxiety Effects 0.000 claims description 5
- 239000000284 extract Substances 0.000 claims description 5
- 230000036651 mood Effects 0.000 claims description 5
- 230000036642 wellbeing Effects 0.000 claims description 5
- 238000004806 packaging method and process Methods 0.000 claims 1
- 244000141009 Hypericum perforatum Species 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 235000002992 Betula pubescens Nutrition 0.000 description 1
- 241001520764 Betula pubescens Species 0.000 description 1
- 239000001692 EU approved anti-caking agent Substances 0.000 description 1
- 241001110062 Euphrasia officinalis Species 0.000 description 1
- 235000010677 Origanum vulgare Nutrition 0.000 description 1
- 240000001745 Rheum palmatum Species 0.000 description 1
- 235000008090 Rheum palmatum Nutrition 0.000 description 1
- DGLFSNZWRYADFC-UHFFFAOYSA-N chembl2334586 Chemical compound C1CCC2=CN=C(N)N=C2C2=C1NC1=CC=C(C#CC(C)(O)C)C=C12 DGLFSNZWRYADFC-UHFFFAOYSA-N 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/38—Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
Descrizione di Brevetto di Invenzione Industriale avente per titolo: ?COMPOSIZIONE PER L?USO NELLA TERAPIA, IN PARTICOLARE PER LA CURA DELLA DEPRESSIONE?. Description of Industrial Invention Patent entitled:? COMPOSITION FOR USE IN THERAPY, IN PARTICULAR FOR THE TREATMENT OF DEPRESSION ?.
CAMPO TECNICO DELL?INVENZIONE TECHNICAL FIELD OF THE INVENTION
La presente invenzione riguarda una nuova composizione, in particolare per l?uso nella terapia di pazienti, pi? in particolare per la cura della depressione, per il miglioramento dell?umore, per il rilassamento, per la cura dell?ansia, per alleviare la tristezza e la disperazione, per migliorare il sonno, per l?incremento delle manifestazioni affettive e del senso di benessere in determinati pazienti. The present invention relates to a new composition, in particular for use in the therapy of patients, more? in particular for the treatment of depression, for the improvement of mood, for relaxation, for the treatment of anxiety, to relieve sadness and despair, to improve sleep, to increase affective manifestations and the sense of well-being in certain patients.
STATO DELLA TECNICA ANTERIORE STATE OF THE PRIOR ART
Sono stati proposti molte composizioni per il trattamento della depressione. Tuttavia, tali composizioni non riescono ad alleviare in maniera efficacie i sintomi della depressione. Many compositions have been proposed for the treatment of depression. However, such compositions fail to effectively alleviate the symptoms of depression.
Peraltro, le stesse composizioni richiedono costosi procedimenti produttivi che si riflettono negativamente sul prezzo finale del prodotto da somministrare. Moreover, the same compositions require expensive production processes which negatively affect the final price of the product to be administered.
SCOPI DELL?INVENZIONE AIMS OF THE INVENTION
Uno scopo della presente invenzione ? quello di fornire una nuova composizione. A purpose of the present invention? to provide a new composition.
Un altro scopo della presente invenzione ? quello di fornire una nuova composizione per l?uso nella terapia in pazienti, in particolare per l?uso nel trattamento o nella cura della depressione, per il miglioramento dell?umore, per il rilassamento, per il trattamento o la cura dell?ansia, per il trattamento o per alleviare la tristezza e la disperazione, per migliorare il sonno e/o per l?incremento delle manifestazioni affettive e del senso di benessere in pazienti in determinati pazienti. Another object of the present invention? to provide a novel composition for use in therapy in patients, particularly for use in the treatment or cure of depression, for the improvement of mood, for relaxation, for the treatment or cure of anxiety, for treatment or to alleviate sadness and despair, to improve sleep and / or to increase the affective manifestations and sense of well-being in patients in certain patients.
Un altro scopo della presente invenzione ? quello di fornire una composizione come sopra indicato che sia semplice e facile da ottenere. Another object of the present invention? that of providing a composition as indicated above which is simple and easy to obtain.
Un altro scopo della presente invenzione ? quello di fornire una composizione come sopra indicato che sia economica da realizzare. Another object of the present invention? that of providing a composition as indicated above which is economical to make.
Conformemente ad un aspetto della presente invenzione ? prevista una composizione secondo la rivendicazione 1. According to an aspect of the present invention? provided a composition according to claim 1.
Conformemente ad un altro aspetto della presente invenzione ? prevista una capsula secondo la rivendicazione 9. According to another aspect of the present invention? a capsule according to claim 9 is provided.
Conformemente ad un ulteriore aspetto della presente invenzione ? prevista una confezione secondo la rivendicazione 10. According to a further aspect of the present invention? a package according to claim 10 is provided.
Le rivendicazioni dipendenti si riferiscono a caratteristiche vantaggiose dell?invenzione. The dependent claims refer to advantageous features of the invention.
ESEMPI DI REALIZZAZIONE DELL?INVENZIONE EXAMPLES OF REALIZATION OF THE INVENTION
La presente invenzione riguarda un preparato o una composizione comprendente i seguenti componenti: The present invention relates to a preparation or a composition comprising the following components:
- iperico (Hypericum perforatum), ad esempio in una percentuale in peso tra 13% e 23% sul peso totale, - St. John's wort (Hypericum perforatum), for example in a percentage by weight between 13% and 23% of the total weight,
- origano (Origanum vulgare), ad esempio in una percentuale in peso tra 2% e 12% sul peso totale, - oregano (Origanum vulgare), for example in a percentage by weight between 2% and 12% of the total weight,
- giglio (Lilium), ad esempio in una percentuale in peso tra 10% e 20% sul peso totale, - lily (Lilium), for example in a percentage by weight between 10% and 20% of the total weight,
- eufrasia (Euphrasia officinalis), ad esempio in una percentuale in peso tra 6% e 16% sul peso totale, - euphrasia (Euphrasia officinalis), for example in a percentage by weight between 6% and 16% of the total weight,
- rabarbaro rosso (Rheum palmatum), ad esempio in una percentuale in peso tra 18% e 28% sul peso totale, - red rhubarb (Rheum palmatum), for example in a percentage by weight between 18% and 28% of the total weight,
- betulla (Betula alba), ad esempio in una percentuale in peso tra 10% e 20% sul peso totale, e - birch (Betula alba), for example in a percentage by weight between 10% and 20% of the total weight, e
- uno o pi? eccipienti, ad esempio in una percentuale in peso (chiaramente in peso complessivo di tutti gli eccipienti presenti) tra 6% e 16% sul peso totale. - one or more? excipients, for example in a percentage by weight (clearly by total weight of all the excipients present) between 6% and 16% of the total weight.
Vantaggiosamente, le percentuali dei suddetti componenti sono come di seguito indicato: Advantageously, the percentages of the aforementioned components are as indicated below:
- iperico in una percentuale in peso tra 17% e 19% sul peso totale, - origano in una percentuale in peso tra 6% e 8% sul peso totale, - hypericum in a percentage by weight between 17% and 19% of the total weight, - oregano in a percentage by weight between 6% and 8% of the total weight,
- giglio in una percentuale in peso tra 14% e 16% sul peso totale, - lily in a percentage by weight between 14% and 16% of the total weight,
- eufrasia in una percentuale in peso tra 10% e 12% sul peso totale, - rabarbaro rosso in una percentuale in peso tra 22% e 24% sul peso totale, - betulla in una percentuale in peso tra 14% e 16% sul peso totale, e - uno o pi? eccipienti in una percentuale in peso (chiaramente in peso complessivo di tutti gli eccipienti presenti) tra 10% e 12% sul peso totale. - euphrasia in a percentage by weight between 10% and 12% of the total weight, - red rhubarb in a percentage by weight between 22% and 24% of the total weight, - birch in a percentage by weight between 14% and 16% by weight total, and - one or more? excipients in a percentage by weight (clearly by total weight of all the excipients present) between 10% and 12% of the total weight.
Una composizione preferita secondo la presente invenzione comprende i suddetti componenti alle percentuali in peso come riportate qui di seguito: A preferred composition according to the present invention comprises the aforementioned components at the percentages by weight as reported below:
- iperico in una percentuale in peso pari a circa il 18% sul peso totale, - origano in una percentuale in peso pari a circa il 7% sul peso totale, - giglio in una percentuale in peso pari a circa il 15% sul peso totale, - eufrasia in una percentuale in peso pari a circa il 11% sul peso totale, - rabarbaro rosso in una percentuale in peso pari a circa il 23% sul peso totale, - hypericum in a percentage by weight of about 18% of the total weight, - oregano in a percentage by weight of about 7% of the total weight, - lily in a percentage by weight of about 15% of the total weight , - euphrasia in a percentage by weight of approximately 11% of the total weight, - red rhubarb in a percentage by weight of approximately 23% of the total weight,
- betulla in una percentuale in peso pari a circa il 15% sul peso totale, - uno o pi? eccipienti in una percentuale in peso (chiaramente in peso complessivo di tutti gli eccipienti presenti) pari a circa il 11% sul peso totale. - birch in a percentage by weight equal to about 15% of the total weight, - one or more? excipients in a percentage by weight (clearly by total weight of all the excipients present) equal to about 11% of the total weight.
Peraltro, almeno uno tra iperico, origano, giglio, eufrasia, rabarbaro rosso e betulla ? presente sotto forma di estratto secco. Di preferenza, tutti tali componenti sono presenti sotto forma di estratti secchi. Moreover, at least one of St. John's wort, oregano, lily, euphrasia, red rhubarb and birch? present in the form of dry extract. Preferably, all such components are present in the form of dry extracts.
Se ? presente l?origano, anch?esso ? vantaggiosamente presente sotto forma di estratto secco. Self ? present l? oregano, too? advantageously present in the form of dry extract.
Per quanto riguarda l?eccipiente o gli eccipienti, con tali termini si intende un componente o componenti che permette/permettono di legare tutti gli altri elementi o componenti insieme. With regard to the excipient or excipients, these terms mean a component or components that allows / allow to bind all the other elements or components together.
Gli eccipienti possono ad esempio comprendere aromi, agenti antiagglomeranti, addensanti, edulcoranti, eccetera. The excipients may for example include flavorings, anti-caking agents, thickeners, sweeteners, etc.
Un preparato o una composizione secondo la presente invenzione ? principalmente per l?uso nella terapia, in particolare per l?uso nel trattamento o nella cura della depressione e/o per il miglioramento dell?umore e/o per il rilassamento e/o per il trattamento o la cura dell?ansia e/o per il trattamento o per alleviare la tristezza e la disperazione e/o per migliorare il sonno e/o per l?incremento delle manifestazioni affettive e del senso di benessere in pazienti. A preparation or a composition according to the present invention? primarily for use in therapy, particularly for use in the treatment or cure of depression and / or for the improvement of mood and / or for relaxation and / or for the treatment or cure of anxiety and / or for the treatment or to alleviate sadness and despair and / or to improve sleep and / or to increase the affective manifestations and sense of well-being in patients.
Peraltro, una composizione in accordo con la presente invenzione pu? essere somministrata in capsule, ad esempio in capsule ciascuna di peso tra circa 0,4 e circa 0,6 g, volendo circa 0,5 g. On the other hand, a composition in accordance with the present invention can? be administered in capsules, for example in capsules each weighing between about 0.4 and about 0.6 g, about 0.5 g if desired.
In merito a ci?, una confezione potrebbe comprende tra 200 e 300 capsule, ad esempio 240 capsule. Regarding this, a package could comprise between 200 and 300 capsules, for example 240 capsules.
Per l?ottenimento di una composizione secondo la presente invenzione, si possono ad esempio essiccare le foglie dei componenti sopra indicati, dopodich? si polverizzano le foglie essiccate in modo da ottenere un preparato di consistenza polverosa con granulometria omogenea fine. To obtain a composition according to the present invention, it is possible, for example, to dry the leaves of the components indicated above, after which it is possible to dry the leaves of the components indicated above. the dried leaves are pulverized in order to obtain a powdery consistency preparation with a fine homogeneous particle size.
Per l?incapsulamento della composizione si pu? invece seguire un procedimento standard. For the encapsulation of the composition you can? instead follow a standard procedure.
La composizione secondo la presente invenzione, in particolare sotto forma di capsule ? stata somministrata, nell?arco di un anno, ad una serie di pazienti, chiaramente umani, e si ? avuto modo di riscontrare che dopo tre settimane continue di somministrazione si verificava un miglioramento dell?umore e si rilevava un rilassamento e una diminuzione dell?ansia dei pazienti umani. The composition according to the present invention, in particular in the form of capsules? was administered, over a year, to a series of patients, clearly human, and yes? was able to find that after three continuous weeks of administration there was an improvement in mood and there was a relaxation and a decrease in anxiety in human patients.
In particolare, si ? avuto modo di notare una netta diminuzione degli episodi di tristezza e disperazione nei pazienti sottoposti al trattamento, mentre miglioravano il sonno, le manifestazioni affettive e il senso di benessere in generale. In particular, yes? had the opportunity to notice a clear decrease in episodes of sadness and despair in patients undergoing treatment, while sleep, affective manifestations and the sense of well-being in general improved.
In generale, la somministrazione di una composizione secondo la presente invenzione migliorava lo stato di depressione dei rispettivi pazienti. In general, the administration of a composition according to the present invention improved the depressed state of the respective patients.
Il trattamento ? stato condotto in particolare somministrando da 1 a 3 capsule al mattino, da 1 a 2 a pranzo e da 1 a 3 la sera. The treatment ? It was conducted in particular by administering 1 to 3 capsules in the morning, 1 to 2 at lunch and 1 to 3 in the evening.
Modifiche e varianti dell?invenzione sono possibili entro l?ambito di protezione definito dalle rivendicazioni. Modifications and variants of the invention are possible within the protection scope defined by the claims.
Claims (10)
Priority Applications (1)
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IT102020000004123A IT202000004123A1 (en) | 2020-02-27 | 2020-02-27 | COMPOSITION FOR USE IN THERAPY, ESPECIALLY FOR THE TREATMENT OF DEPRESSION |
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IT102020000004123A IT202000004123A1 (en) | 2020-02-27 | 2020-02-27 | COMPOSITION FOR USE IN THERAPY, ESPECIALLY FOR THE TREATMENT OF DEPRESSION |
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Citations (6)
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WO2008017484A1 (en) * | 2006-08-09 | 2008-02-14 | Dsm Ip Assets B.V. | Novel agents for the treatment of disorders connected to impaired neurotransmission |
US20170232050A1 (en) * | 2016-02-16 | 2017-08-17 | David ELLERY | Herbal formulation for treating chronic fatigue syndrome |
CN107712536A (en) * | 2017-11-02 | 2018-02-23 | 成都金川田农机制造有限公司 | A kind of health honey solids drink formula |
CN108159036A (en) * | 2018-02-12 | 2018-06-15 | 成都图径生物科技有限公司 | Composition for relieving asthenopia containing theanine, phosphatidylserine and procyanidine |
CN108354918A (en) * | 2018-02-12 | 2018-08-03 | 成都图径生物科技有限公司 | Composition for relieving asthenopia containing theanine, γ-aminobutyric acid and procyanidine |
KR20190050186A (en) * | 2017-11-02 | 2019-05-10 | 배예슬 | A solid type stick perfume composition containing a phytoncide flavor, and a process for producing the same |
-
2020
- 2020-02-27 IT IT102020000004123A patent/IT202000004123A1/en unknown
Patent Citations (6)
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WO2008017484A1 (en) * | 2006-08-09 | 2008-02-14 | Dsm Ip Assets B.V. | Novel agents for the treatment of disorders connected to impaired neurotransmission |
US20170232050A1 (en) * | 2016-02-16 | 2017-08-17 | David ELLERY | Herbal formulation for treating chronic fatigue syndrome |
CN107712536A (en) * | 2017-11-02 | 2018-02-23 | 成都金川田农机制造有限公司 | A kind of health honey solids drink formula |
KR20190050186A (en) * | 2017-11-02 | 2019-05-10 | 배예슬 | A solid type stick perfume composition containing a phytoncide flavor, and a process for producing the same |
CN108159036A (en) * | 2018-02-12 | 2018-06-15 | 成都图径生物科技有限公司 | Composition for relieving asthenopia containing theanine, phosphatidylserine and procyanidine |
CN108354918A (en) * | 2018-02-12 | 2018-08-03 | 成都图径生物科技有限公司 | Composition for relieving asthenopia containing theanine, γ-aminobutyric acid and procyanidine |
Non-Patent Citations (4)
Title |
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DATABASE WPI Week 201820, Derwent World Patents Index; AN 2018-16845T, XP002801114 * |
DATABASE WPI Week 201846, Derwent World Patents Index; AN 2018-493282, XP002801113 * |
DATABASE WPI Week 201864, Derwent World Patents Index; AN 2018-62989Y, XP002801112 * |
DATABASE WPI Week 201951, Derwent World Patents Index; AN 2019-44944D, XP002801115 * |
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