IT201900008391A1 - Procedimento di preparazione del polimorfo f di sodio neridronato - Google Patents
Procedimento di preparazione del polimorfo f di sodio neridronatoInfo
- Publication number
- IT201900008391A1 IT201900008391A1 IT102019000008391A IT201900008391A IT201900008391A1 IT 201900008391 A1 IT201900008391 A1 IT 201900008391A1 IT 102019000008391 A IT102019000008391 A IT 102019000008391A IT 201900008391 A IT201900008391 A IT 201900008391A IT 201900008391 A1 IT201900008391 A1 IT 201900008391A1
- Authority
- IT
- Italy
- Prior art keywords
- nerhydronate
- polymorph
- sodium
- preparing
- procedure
- Prior art date
Links
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 title 1
- 229910052708 sodium Inorganic materials 0.000 title 1
- 239000011734 sodium Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT102019000008391A IT201900008391A1 (it) | 2019-06-07 | 2019-06-07 | Procedimento di preparazione del polimorfo f di sodio neridronato |
ES20736424T ES2967423T3 (es) | 2019-06-07 | 2020-06-05 | Procedimiento para la preparación del polimorfo F de neridronato de sodio |
MX2021015053A MX2021015053A (es) | 2019-06-07 | 2020-06-05 | Proceso de preparacion del polimorfo f de neridronato de sodio. |
JP2021572271A JP7162973B2 (ja) | 2019-06-07 | 2020-06-05 | ネリドロン酸ナトリウムの多形fの製造方法 |
PCT/IB2020/055304 WO2020245780A1 (en) | 2019-06-07 | 2020-06-05 | Process for the preparation of the polymorph f of sodium neridronate |
HRP20231668TT HRP20231668T1 (hr) | 2019-06-07 | 2020-06-05 | Postupak za pripravu polimorfa f natrijevog neridronata |
SI202030345T SI3980434T1 (sl) | 2019-06-07 | 2020-06-05 | Postopek za pripravo polimorfa f natrijevega neridronata |
DK20736424.1T DK3980434T3 (da) | 2019-06-07 | 2020-06-05 | Fremgangsmåde til fremstilling af polymorph af natriumneridronat |
PL20736424.1T PL3980434T3 (pl) | 2019-06-07 | 2020-06-05 | Sposób wytwarzania polimorfu f neridronianu sodu |
LTEPPCT/IB2020/055304T LT3980434T (lt) | 2019-06-07 | 2020-06-05 | Natrio neridronato polimorfo f gavimo būdas |
FIEP20736424.1T FI3980434T3 (fi) | 2019-06-07 | 2020-06-05 | Menetelmä natriumneridronaatin polymorfi f:n valmistamiseksi |
US17/595,992 US11512104B2 (en) | 2019-06-07 | 2020-06-05 | Process for the preparation of the polymorph F of sodium neridronate |
HUE20736424A HUE065645T2 (hu) | 2019-06-07 | 2020-06-05 | Eljárás nátrium-neridronát F poliformjának elõállítására |
PT207364241T PT3980434T (pt) | 2019-06-07 | 2020-06-05 | Processo para a preparação do polimorfo f de neridronato de sódio |
AU2020289084A AU2020289084B2 (en) | 2019-06-07 | 2020-06-05 | Process for the preparation of the polymorph f of sodium neridronate |
CN202080041274.9A CN113906039A (zh) | 2019-06-07 | 2020-06-05 | 用于制备奈立膦酸钠的多晶型物f的工艺 |
CA3142232A CA3142232C (en) | 2019-06-07 | 2020-06-05 | Process for the preparation of the polymorph f of sodium neridronate |
EP20736424.1A EP3980434B1 (en) | 2019-06-07 | 2020-06-05 | Process for the preparation of the polymorph f of sodium neridronate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT102019000008391A IT201900008391A1 (it) | 2019-06-07 | 2019-06-07 | Procedimento di preparazione del polimorfo f di sodio neridronato |
Publications (1)
Publication Number | Publication Date |
---|---|
IT201900008391A1 true IT201900008391A1 (it) | 2020-12-07 |
Family
ID=68234108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT102019000008391A IT201900008391A1 (it) | 2019-06-07 | 2019-06-07 | Procedimento di preparazione del polimorfo f di sodio neridronato |
Country Status (18)
Country | Link |
---|---|
US (1) | US11512104B2 (it) |
EP (1) | EP3980434B1 (it) |
JP (1) | JP7162973B2 (it) |
CN (1) | CN113906039A (it) |
AU (1) | AU2020289084B2 (it) |
CA (1) | CA3142232C (it) |
DK (1) | DK3980434T3 (it) |
ES (1) | ES2967423T3 (it) |
FI (1) | FI3980434T3 (it) |
HR (1) | HRP20231668T1 (it) |
HU (1) | HUE065645T2 (it) |
IT (1) | IT201900008391A1 (it) |
LT (1) | LT3980434T (it) |
MX (1) | MX2021015053A (it) |
PL (1) | PL3980434T3 (it) |
PT (1) | PT3980434T (it) |
SI (1) | SI3980434T1 (it) |
WO (1) | WO2020245780A1 (it) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008004000A1 (en) * | 2006-07-03 | 2008-01-10 | Generics [Uk] Limited | Novel process for the preparation of bisphosphonic acids |
EP3553067A1 (en) * | 2018-04-10 | 2019-10-16 | Abiogen Pharma S.p.A. | Polymorph of sodium neridronate and preparation process thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4304734A (en) * | 1980-10-16 | 1981-12-08 | Vysoka Skola Chemicko-Technologicka | 6-Amino-1-hydroxyhexylidene diphosphonic acid, salts and a process for production thereof |
IT1246992B (it) * | 1991-01-08 | 1994-12-12 | Gentili Ist Spa | Procedimento per la preparazione di acidi difosfonici e loro sali |
ITMI20040218A1 (it) * | 2004-02-10 | 2004-05-10 | Abiogen Pharma Spa | Uso di neridronato sodico per promuovere la neoformazione ossea |
JP2007042359A (ja) * | 2005-08-02 | 2007-02-15 | Hst Kk | 押釦型スイッチ |
CN104628768A (zh) * | 2015-03-06 | 2015-05-20 | 江苏正大清江制药有限公司 | 一种伊班膦酸钠的制备方法 |
-
2019
- 2019-06-07 IT IT102019000008391A patent/IT201900008391A1/it unknown
-
2020
- 2020-06-05 ES ES20736424T patent/ES2967423T3/es active Active
- 2020-06-05 AU AU2020289084A patent/AU2020289084B2/en active Active
- 2020-06-05 PL PL20736424.1T patent/PL3980434T3/pl unknown
- 2020-06-05 LT LTEPPCT/IB2020/055304T patent/LT3980434T/lt unknown
- 2020-06-05 US US17/595,992 patent/US11512104B2/en active Active
- 2020-06-05 CN CN202080041274.9A patent/CN113906039A/zh active Pending
- 2020-06-05 MX MX2021015053A patent/MX2021015053A/es unknown
- 2020-06-05 WO PCT/IB2020/055304 patent/WO2020245780A1/en active Application Filing
- 2020-06-05 HU HUE20736424A patent/HUE065645T2/hu unknown
- 2020-06-05 SI SI202030345T patent/SI3980434T1/sl unknown
- 2020-06-05 JP JP2021572271A patent/JP7162973B2/ja active Active
- 2020-06-05 CA CA3142232A patent/CA3142232C/en active Active
- 2020-06-05 DK DK20736424.1T patent/DK3980434T3/da active
- 2020-06-05 PT PT207364241T patent/PT3980434T/pt unknown
- 2020-06-05 HR HRP20231668TT patent/HRP20231668T1/hr unknown
- 2020-06-05 FI FIEP20736424.1T patent/FI3980434T3/fi active
- 2020-06-05 EP EP20736424.1A patent/EP3980434B1/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008004000A1 (en) * | 2006-07-03 | 2008-01-10 | Generics [Uk] Limited | Novel process for the preparation of bisphosphonic acids |
EP3553067A1 (en) * | 2018-04-10 | 2019-10-16 | Abiogen Pharma S.p.A. | Polymorph of sodium neridronate and preparation process thereof |
Non-Patent Citations (1)
Title |
---|
KIECZYKOWSKI G R: "Preparation of (4-amino-1-hydroxybutylidene)bisphosphonic acid sodium salt, MK217 (ALENDRONATE SODIUM). AN IMPROVED PROCEDURE FOR THE PREPARATION OF 1-HYDROXY-1,1,-BISPHOSPHONIC ACIDS", JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 60, no. 25, 1 January 1995 (1995-01-01), pages 8310 - 8312, XP002162672, ISSN: 0022-3263, DOI: 10.1021/JO00130A036 * |
Also Published As
Publication number | Publication date |
---|---|
EP3980434B1 (en) | 2023-10-04 |
US20220267359A1 (en) | 2022-08-25 |
PT3980434T (pt) | 2023-12-28 |
CA3142232A1 (en) | 2020-12-10 |
MX2021015053A (es) | 2022-08-23 |
LT3980434T (lt) | 2024-01-25 |
HUE065645T2 (hu) | 2024-06-28 |
CN113906039A (zh) | 2022-01-07 |
PL3980434T3 (pl) | 2024-03-25 |
SI3980434T1 (sl) | 2024-02-29 |
DK3980434T3 (da) | 2024-01-02 |
ES2967423T3 (es) | 2024-04-30 |
HRP20231668T1 (hr) | 2024-03-15 |
JP2022528292A (ja) | 2022-06-09 |
CA3142232C (en) | 2022-12-06 |
JP7162973B2 (ja) | 2022-10-31 |
AU2020289084A1 (en) | 2022-01-06 |
EP3980434A1 (en) | 2022-04-13 |
FI3980434T3 (fi) | 2023-12-28 |
US11512104B2 (en) | 2022-11-29 |
AU2020289084B2 (en) | 2022-04-14 |
WO2020245780A1 (en) | 2020-12-10 |
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