IT201700084299A1 - Peptides derived from GAP24 for use in the treatment of the X form of Charcot-Marie-Tooth peripheral neuropathy - Google Patents

Peptides derived from GAP24 for use in the treatment of the X form of Charcot-Marie-Tooth peripheral neuropathy

Info

Publication number
IT201700084299A1
IT201700084299A1 IT102017000084299A IT201700084299A IT201700084299A1 IT 201700084299 A1 IT201700084299 A1 IT 201700084299A1 IT 102017000084299 A IT102017000084299 A IT 102017000084299A IT 201700084299 A IT201700084299 A IT 201700084299A IT 201700084299 A1 IT201700084299 A1 IT 201700084299A1
Authority
IT
Italy
Prior art keywords
gap24
charcot
marie
treatment
peripheral neuropathy
Prior art date
Application number
IT102017000084299A
Other languages
Italian (it)
Inventor
Mario Bortolozzi
Andrea Carrer
Alessandro Leparulo
Original Assignee
Univ Degli Studi Padova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Padova filed Critical Univ Degli Studi Padova
Priority to IT102017000084299A priority Critical patent/IT201700084299A1/en
Priority to PCT/EP2018/068765 priority patent/WO2019020374A1/en
Publication of IT201700084299A1 publication Critical patent/IT201700084299A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
IT102017000084299A 2017-07-24 2017-07-24 Peptides derived from GAP24 for use in the treatment of the X form of Charcot-Marie-Tooth peripheral neuropathy IT201700084299A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT102017000084299A IT201700084299A1 (en) 2017-07-24 2017-07-24 Peptides derived from GAP24 for use in the treatment of the X form of Charcot-Marie-Tooth peripheral neuropathy
PCT/EP2018/068765 WO2019020374A1 (en) 2017-07-24 2018-07-11 Gap24-derived peptides for use in the treatment of the x-linked form of charcot-marie-tooth peripheral neuropathy

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102017000084299A IT201700084299A1 (en) 2017-07-24 2017-07-24 Peptides derived from GAP24 for use in the treatment of the X form of Charcot-Marie-Tooth peripheral neuropathy

Publications (1)

Publication Number Publication Date
IT201700084299A1 true IT201700084299A1 (en) 2019-01-24

Family

ID=60628048

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102017000084299A IT201700084299A1 (en) 2017-07-24 2017-07-24 Peptides derived from GAP24 for use in the treatment of the X form of Charcot-Marie-Tooth peripheral neuropathy

Country Status (2)

Country Link
IT (1) IT201700084299A1 (en)
WO (1) WO2019020374A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2305274A1 (en) * 2009-09-21 2011-04-06 Centre National de la Recherche Scientifique (CNRS) Use of WNT stimulators for treating demyelinating diseases
WO2014095468A1 (en) * 2012-12-19 2014-06-26 Universiteit Gent Use of connexin channel inhibitors to protect grafts

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4612132A (en) 1984-07-20 1986-09-16 Chevron Research Company Modified succinimides
US5643873A (en) 1992-05-06 1997-07-01 Affymax Technologies N.V. Peptides and compounds that bind selectins including endothelial leukocyte adhesion molecule 1
WO1993024135A1 (en) 1992-05-26 1993-12-09 Immunex Corporation Novel cytokine that binds cd30
US5654276A (en) 1995-06-07 1997-08-05 Affymax Technologies N.V. Peptides and compounds that bind to the IL-5 receptor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2305274A1 (en) * 2009-09-21 2011-04-06 Centre National de la Recherche Scientifique (CNRS) Use of WNT stimulators for treating demyelinating diseases
WO2014095468A1 (en) * 2012-12-19 2014-06-26 Universiteit Gent Use of connexin channel inhibitors to protect grafts

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
A CARRER ET AL.: "Cx32 hemichannel opening by cytosolic Ca2+ is inhibited by the R220X mutation that causes Charcot-Marie-Tooth disease", HUMAN MOLECULAR GENETICS, vol. 27, no. 1, 1 January 2018 (2018-01-01), Oxford University Press, pages 80 - 94, XP002779523, ISSN: 0964-6906 *
J WANG ET AL.: "Modulation of membrane channel currents by gap junction protein mimetic peptides; size matters", AMERICAN JOURNAL OF PHYSIOLOGY, vol. 293, no. 3(1), 22 July 2007 (2007-07-22), American Physiological Society, pages c1112 - c1119, XP009102112, ISSN: 0002-9513 *

Also Published As

Publication number Publication date
WO2019020374A1 (en) 2019-01-31

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