IT201600121375A1 - PROCESS FOR THE PREPARATION OF 3ß-HYDROXY-17- (1H-BENZIMIDAZOL-1-IL) ANDROSTA-5,16-DIENE - Google Patents

PROCESS FOR THE PREPARATION OF 3ß-HYDROXY-17- (1H-BENZIMIDAZOL-1-IL) ANDROSTA-5,16-DIENE

Info

Publication number
IT201600121375A1
IT201600121375A1 IT102016000121375A IT201600121375A IT201600121375A1 IT 201600121375 A1 IT201600121375 A1 IT 201600121375A1 IT 102016000121375 A IT102016000121375 A IT 102016000121375A IT 201600121375 A IT201600121375 A IT 201600121375A IT 201600121375 A1 IT201600121375 A1 IT 201600121375A1
Authority
IT
Italy
Prior art keywords
androsta
benzimidazol
diene
hydroxy
preparation
Prior art date
Application number
IT102016000121375A
Other languages
Italian (it)
Inventor
Francesco Barbieri
Roberto Lenna
Original Assignee
Ind Chimica Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ind Chimica Srl filed Critical Ind Chimica Srl
Priority to IT102016000121375A priority Critical patent/IT201600121375A1/en
Priority to US16/323,317 priority patent/US11390645B2/en
Priority to PCT/EP2017/070124 priority patent/WO2018029223A1/en
Priority to CA3063339A priority patent/CA3063339A1/en
Priority to RU2019143855A priority patent/RU2749134C1/en
Priority to CH00147/19A priority patent/CH714173B1/en
Priority to ES201990014A priority patent/ES2700901B2/en
Publication of IT201600121375A1 publication Critical patent/IT201600121375A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
IT102016000121375A 2016-08-08 2016-11-30 PROCESS FOR THE PREPARATION OF 3ß-HYDROXY-17- (1H-BENZIMIDAZOL-1-IL) ANDROSTA-5,16-DIENE IT201600121375A1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT102016000121375A IT201600121375A1 (en) 2016-11-30 2016-11-30 PROCESS FOR THE PREPARATION OF 3ß-HYDROXY-17- (1H-BENZIMIDAZOL-1-IL) ANDROSTA-5,16-DIENE
US16/323,317 US11390645B2 (en) 2016-08-08 2017-08-08 Process for the preparation of 3β-hydroxy-17-(1H-benzimidazol-1-YL) androsta-5,16-diene
PCT/EP2017/070124 WO2018029223A1 (en) 2016-08-08 2017-08-08 PROCESS FOR THE PREPARATION OF 3ß-HYDROXY-17-(1H-BENZIMIDAZOL-1-YL)ANDROSTA-5,16-DIENE
CA3063339A CA3063339A1 (en) 2016-08-08 2017-08-08 Process for the preparation of 3b-hydroxy-17-(1h-benzimidazol-1-yl)androsta-5,16-diene
RU2019143855A RU2749134C1 (en) 2016-08-08 2017-08-08 METHOD FOR SYNTHESIS OF 3β-HYDROXY-17-(1H-BENZIMIDAZOL-1-YL)ANDROSTA-5,16-DIENE
CH00147/19A CH714173B1 (en) 2016-08-08 2017-08-08 Process for the preparation of 3ß-hydroxy-17- (1H-benzimidazol-1-yl) androsta-5,16-diene.
ES201990014A ES2700901B2 (en) 2016-08-08 2017-08-08 Process for the preparation of 3β-hydroxy-17- (1h-benzimidazol-1-yl) androsta-5,16-diene.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102016000121375A IT201600121375A1 (en) 2016-11-30 2016-11-30 PROCESS FOR THE PREPARATION OF 3ß-HYDROXY-17- (1H-BENZIMIDAZOL-1-IL) ANDROSTA-5,16-DIENE

Publications (1)

Publication Number Publication Date
IT201600121375A1 true IT201600121375A1 (en) 2018-05-30

Family

ID=58401994

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102016000121375A IT201600121375A1 (en) 2016-08-08 2016-11-30 PROCESS FOR THE PREPARATION OF 3ß-HYDROXY-17- (1H-BENZIMIDAZOL-1-IL) ANDROSTA-5,16-DIENE

Country Status (1)

Country Link
IT (1) IT201600121375A1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006093993A1 (en) * 2005-03-02 2006-09-08 University Of Maryland Novel c-17-heteroaryl steroidal cyp17 inhibitors/antiandrogens: synthesis, in vitro biological activities, pharmacokinetics and antitumor activity
WO2009120565A2 (en) * 2008-03-25 2009-10-01 University Of Maryland, Baltimore Novel prodrugs of c-17-heteroaryl steroidal cyp17 inhibitors/antiandrogens: synthesis, in vitro biological activities, pharmacokinetics and antitumor activity
WO2016119742A1 (en) * 2015-01-29 2016-08-04 苏州晶云药物科技有限公司 (3β)-17-(1h-benzimidazole-1-yl)androstane-5, and 16-diene-3-ol salts and preparation methods therefor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006093993A1 (en) * 2005-03-02 2006-09-08 University Of Maryland Novel c-17-heteroaryl steroidal cyp17 inhibitors/antiandrogens: synthesis, in vitro biological activities, pharmacokinetics and antitumor activity
WO2009120565A2 (en) * 2008-03-25 2009-10-01 University Of Maryland, Baltimore Novel prodrugs of c-17-heteroaryl steroidal cyp17 inhibitors/antiandrogens: synthesis, in vitro biological activities, pharmacokinetics and antitumor activity
WO2016119742A1 (en) * 2015-01-29 2016-08-04 苏州晶云药物科技有限公司 (3β)-17-(1h-benzimidazole-1-yl)androstane-5, and 16-diene-3-ol salts and preparation methods therefor

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