IT1405761B1 - GT APTAMERIC OLIGONUCLEOTIDS AND THEIR USE AS ANTI-HUMAN AGENTS - Google Patents

GT APTAMERIC OLIGONUCLEOTIDS AND THEIR USE AS ANTI-HUMAN AGENTS

Info

Publication number
IT1405761B1
IT1405761B1 ITPD2010A000272A ITPD20100272A IT1405761B1 IT 1405761 B1 IT1405761 B1 IT 1405761B1 IT PD2010A000272 A ITPD2010A000272 A IT PD2010A000272A IT PD20100272 A ITPD20100272 A IT PD20100272A IT 1405761 B1 IT1405761 B1 IT 1405761B1
Authority
IT
Italy
Prior art keywords
oligonucleotids
aptameric
human agents
agents
human
Prior art date
Application number
ITPD2010A000272A
Other languages
Italian (it)
Inventor
Gabriele Grassi
Bruna Scaggiante
Original Assignee
Univ Degli Studi Trieste
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Trieste filed Critical Univ Degli Studi Trieste
Priority to ITPD2010A000272A priority Critical patent/IT1405761B1/en
Priority to PCT/EP2011/065738 priority patent/WO2012034969A1/en
Publication of ITPD20100272A1 publication Critical patent/ITPD20100272A1/en
Application granted granted Critical
Publication of IT1405761B1 publication Critical patent/IT1405761B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers
ITPD2010A000272A 2010-09-13 2010-09-13 GT APTAMERIC OLIGONUCLEOTIDS AND THEIR USE AS ANTI-HUMAN AGENTS IT1405761B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ITPD2010A000272A IT1405761B1 (en) 2010-09-13 2010-09-13 GT APTAMERIC OLIGONUCLEOTIDS AND THEIR USE AS ANTI-HUMAN AGENTS
PCT/EP2011/065738 WO2012034969A1 (en) 2010-09-13 2011-09-12 Gt aptamer oligonucleotides and use thereof as antitumor agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITPD2010A000272A IT1405761B1 (en) 2010-09-13 2010-09-13 GT APTAMERIC OLIGONUCLEOTIDS AND THEIR USE AS ANTI-HUMAN AGENTS

Publications (2)

Publication Number Publication Date
ITPD20100272A1 ITPD20100272A1 (en) 2012-03-14
IT1405761B1 true IT1405761B1 (en) 2014-01-24

Family

ID=43707782

Family Applications (1)

Application Number Title Priority Date Filing Date
ITPD2010A000272A IT1405761B1 (en) 2010-09-13 2010-09-13 GT APTAMERIC OLIGONUCLEOTIDS AND THEIR USE AS ANTI-HUMAN AGENTS

Country Status (2)

Country Link
IT (1) IT1405761B1 (en)
WO (1) WO2012034969A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1277025B1 (en) * 1995-12-04 1997-11-04 Cooperativa Centro Ricerche Po CLASS OF PHOSPHODIESTERIC OLIGONUCLEOTIDES WITH CYTOTOXIC ACTIVITY PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND THEIR USE

Also Published As

Publication number Publication date
ITPD20100272A1 (en) 2012-03-14
WO2012034969A1 (en) 2012-03-22

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