IT1401451B1 - Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo. - Google Patents
Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo.Info
- Publication number
- IT1401451B1 IT1401451B1 ITMI2010A001047A ITMI20101047A IT1401451B1 IT 1401451 B1 IT1401451 B1 IT 1401451B1 IT MI2010A001047 A ITMI2010A001047 A IT MI2010A001047A IT MI20101047 A ITMI20101047 A IT MI20101047A IT 1401451 B1 IT1401451 B1 IT 1401451B1
- Authority
- IT
- Italy
- Prior art keywords
- diisopropylaminous
- chromen
- phenylpropyl
- dihydro
- hydroxymethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2010A001047A IT1401451B1 (it) | 2010-06-10 | 2010-06-10 | Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo. |
ES11724778.3T ES2522549T3 (es) | 2010-06-10 | 2011-04-29 | Procedimiento para la preparación de 2-hidroxi-4-fenil-3,4-dihidro-2H-cromen-6-il-metanol y (R)-feso-deacilo |
US13/702,403 US8946456B2 (en) | 2010-06-10 | 2011-04-29 | Process for the preparation of 2-hydroxy-4-phenyl-3,4-dihydro-2H-chromen-6-yl-methanol and (R)-feso-deacyl |
EP11724778.3A EP2580203B1 (en) | 2010-06-10 | 2011-04-29 | Process for the preparation of 2-hydroxy-4-phenyl-3,4-dihydro-2h-chromen-6-yl-methanol and (r)-feso-deacyl |
PCT/IB2011/051896 WO2011154854A1 (en) | 2010-06-10 | 2011-04-29 | Process for the preparation of 2 -hydroxy- 4 -phenyl -3, 4 -dihydro-2h-chromen- 6 -yl -methanol and (r) - feso - deacyl |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2010A001047A IT1401451B1 (it) | 2010-06-10 | 2010-06-10 | Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo. |
Publications (2)
Publication Number | Publication Date |
---|---|
ITMI20101047A1 ITMI20101047A1 (it) | 2011-12-11 |
IT1401451B1 true IT1401451B1 (it) | 2013-07-26 |
Family
ID=43385734
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI2010A001047A IT1401451B1 (it) | 2010-06-10 | 2010-06-10 | Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo. |
Country Status (5)
Country | Link |
---|---|
US (1) | US8946456B2 (it) |
EP (1) | EP2580203B1 (it) |
ES (1) | ES2522549T3 (it) |
IT (1) | IT1401451B1 (it) |
WO (1) | WO2011154854A1 (it) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20121232A1 (it) | 2012-07-16 | 2014-01-17 | Cambrex Profarmaco Milano Srl | Procedimento per la preparazione di 2-(3-n,n-diisopropilamino-1-fenilpropil)-4-idrossimetil-fenolo e suoi derivati |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9203318D0 (sv) | 1992-11-06 | 1992-11-06 | Kabi Pharmacia Ab | Novel 3,3-diphenylpropylamines, their use and preparation |
EP0957073A1 (en) | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Novel derivatives of 3,3-diphenylpropylamines |
DE29923134U1 (de) * | 1999-11-16 | 2000-06-29 | Sanol Arznei Schwarz Gmbh | Stabile Salze neuartiger Derviate von 3,3-Diphenylpropylaminen |
DE10028443C1 (de) | 2000-06-14 | 2002-05-29 | Sanol Arznei Schwarz Gmbh | Verfahren zur Herstellung von 3,3-Diarylpropylaminen, (R,S)- und (R)-4-Phenyl-2-chromanon-6-carbonsäure sowie (R)-4-Phenyl-2-chromanon-carbonsäure-cinchonidinsalz und deren Verwendung zur Herstellung eines rechtsdrehenden Hydroxybenzylalkohols und von pharmazeutischen Zusammensetzungen |
CA2492437A1 (en) * | 2002-07-31 | 2004-02-12 | Schering Ag | New effector conjugates, process for their production and their pharmaceutical use |
JP2008528491A (ja) * | 2005-01-20 | 2008-07-31 | アレイ バイオファーマ、インコーポレイテッド | 免疫調節性障害および呼吸器の疾患の処置のための大環状アナログ |
BRPI0712037A2 (pt) * | 2006-05-24 | 2011-12-20 | Pfizer Ltd | processo para a produção de derivados benzopiran-2-ol |
WO2010018484A1 (en) * | 2008-08-14 | 2010-02-18 | Pfizer Limited | New uses of diisopropylamine derivatives |
-
2010
- 2010-06-10 IT ITMI2010A001047A patent/IT1401451B1/it active
-
2011
- 2011-04-29 EP EP11724778.3A patent/EP2580203B1/en not_active Not-in-force
- 2011-04-29 WO PCT/IB2011/051896 patent/WO2011154854A1/en active Application Filing
- 2011-04-29 US US13/702,403 patent/US8946456B2/en not_active Expired - Fee Related
- 2011-04-29 ES ES11724778.3T patent/ES2522549T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
ES2522549T3 (es) | 2014-11-17 |
WO2011154854A9 (en) | 2013-01-31 |
ITMI20101047A1 (it) | 2011-12-11 |
US8946456B2 (en) | 2015-02-03 |
EP2580203B1 (en) | 2014-08-13 |
EP2580203A1 (en) | 2013-04-17 |
WO2011154854A1 (en) | 2011-12-15 |
US20130079532A1 (en) | 2013-03-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112014026802A2 (pt) | processo para a preparação de um a, \omega-cn diol. | |
IT1405680B1 (it) | Processo per la produzione di l-fucosio. | |
BRPI1015103A2 (pt) | processo de fabricação de calçados com sulcos. | |
BR112014015994A2 (pt) | processo. | |
DK2661243T3 (da) | Konstruktioner, opnåede ved vævsteknologi | |
BR112013009486A2 (pt) | processo para preparação de formas de dosagem gastrirretentivas multiparticuladas | |
BRPI0911898A2 (pt) | processo para preparar compostos, e, composto. | |
BRPI0911531A2 (pt) | processo para preparar iopromida, e, composto. | |
BRPI1014547A2 (pt) | composto, e, processo para preparar um composto. | |
BR112013018945A2 (pt) | processo para a preparação de 4-amino-5-fluoro-3-halo-6-(substituído)picolinatos. | |
BR112015009707A2 (pt) | aparelho de montagem de canal de retorno para um compressor centrífugo, aparelho compressor centrífugo e método para manter o desempenho de um compressor centrífugo". | |
BRPI1011888A2 (pt) | processo para preparar um composto, e, composição. | |
IT1402415B1 (it) | Macchina per maglieria, particolarmente ad elevata finezza. | |
BRPI0909280A2 (pt) | processo para preparar uretanos. | |
BR112013012873A2 (pt) | processo para preparar uma n, n-dialquiletanolamina | |
BR112013018942A2 (pt) | processo para o preparo de 4-amino-3-cloro-5-fluro-6(substituído) picolinatos. | |
BRPI1014691A2 (pt) | Composto, e, processo para a preparação de um composto. | |
BRPI1008987A2 (pt) | processo para preparar 3,3,3-trifluoropropeno | |
BR112012000258A2 (pt) | processo para preparar uma alquenona. | |
IT1397962B1 (it) | Processo per la preparazione del nebivololo. | |
SMT201600006B (it) | Processo per la preparazione del nebivololo | |
ITMI20110647A1 (it) | Procedimento migliorato per la preparazione di 1-(6-metilpiridin-3-il)-2-[4-(metilsolfonil)fenil]etanone, un intermedio dell'etoricoxib. | |
DK3318881T3 (da) | Fremgangsmåde til overvågning af Gaucher's sygdom | |
IT1401109B1 (it) | Nuovo processo per la preparazione di tapentadol e suoi intermedi. | |
BR112012012449A2 (pt) | "processo para preparar 2-isoxazolinas 5,5-dissubstituídas" |