IT1398977B1 - Agente anticancro specifico per i tumori cerebrali con meccanismo di soppressione di recq1 - Google Patents

Agente anticancro specifico per i tumori cerebrali con meccanismo di soppressione di recq1

Info

Publication number
IT1398977B1
IT1398977B1 ITRM2009A000328A ITRM20090328A IT1398977B1 IT 1398977 B1 IT1398977 B1 IT 1398977B1 IT RM2009A000328 A ITRM2009A000328 A IT RM2009A000328A IT RM20090328 A ITRM20090328 A IT RM20090328A IT 1398977 B1 IT1398977 B1 IT 1398977B1
Authority
IT
Italy
Prior art keywords
recq1
pant
suppression mechanism
agent specific
cerebral
Prior art date
Application number
ITRM2009A000328A
Other languages
English (en)
Inventor
Giorgio Stanta
Miran Skrap
Serena Bonin
Marco Vindigni
Alessandro Vindigni
Federico Odreman
Valentina Faoro
Ramiro Mendoza-Maldonado
Matteo Berti
Original Assignee
Icgeb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icgeb filed Critical Icgeb
Priority to ITRM2009A000328A priority Critical patent/IT1398977B1/it
Priority to PCT/IB2010/052763 priority patent/WO2010150159A1/en
Publication of ITRM20090328A1 publication Critical patent/ITRM20090328A1/it
Application granted granted Critical
Publication of IT1398977B1 publication Critical patent/IT1398977B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
    • C12Y306/04—Hydrolases acting on acid anhydrides (3.6) acting on acid anhydrides; involved in cellular and subcellular movement (3.6.4)
    • C12Y306/04012—DNA helicase (3.6.4.12)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ITRM2009A000328A 2009-06-25 2009-06-25 Agente anticancro specifico per i tumori cerebrali con meccanismo di soppressione di recq1 IT1398977B1 (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ITRM2009A000328A IT1398977B1 (it) 2009-06-25 2009-06-25 Agente anticancro specifico per i tumori cerebrali con meccanismo di soppressione di recq1
PCT/IB2010/052763 WO2010150159A1 (en) 2009-06-25 2010-06-18 Anticancer agent specific for brain tumors with mechanism of recq1 suppression

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM2009A000328A IT1398977B1 (it) 2009-06-25 2009-06-25 Agente anticancro specifico per i tumori cerebrali con meccanismo di soppressione di recq1

Publications (2)

Publication Number Publication Date
ITRM20090328A1 ITRM20090328A1 (it) 2010-12-26
IT1398977B1 true IT1398977B1 (it) 2013-03-28

Family

ID=41818364

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM2009A000328A IT1398977B1 (it) 2009-06-25 2009-06-25 Agente anticancro specifico per i tumori cerebrali con meccanismo di soppressione di recq1

Country Status (2)

Country Link
IT (1) IT1398977B1 (it)
WO (1) WO2010150159A1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10548990B2 (en) 2015-07-31 2020-02-04 Genecare Research Institute Co., Ltd. Modified siRNA and pharmaceutical composition
CA3126833A1 (en) * 2019-01-29 2020-08-06 University Of Washington A method of gene editing
WO2021132648A1 (ja) * 2019-12-27 2021-07-01 ルクサナバイオテク株式会社 Ｒｅｃｑｌの発現を阻害するアンチセンスオリゴヌクレオチド及びその用途
WO2024004779A1 (ja) * 2022-06-30 2024-01-04 株式会社ジーンケア研究所 ＲｅｃＱＬ１ヘリカーゼ遺伝子を標的とするｓｉＲＮＡ

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001077350A2 (en) 2000-04-07 2001-10-18 Large Scale Biology Corporation Compositions and methods for inhibiting gene expression
ITRM20030196A1 (it) 2003-04-24 2004-10-25 Sigma Tau Ind Farmaceuti Uso di reagenti per la preparazione di un medicamento
US20070243570A1 (en) * 2003-05-19 2007-10-18 Genecare Research Institute Co., Ltd Apoptosis Inducer for Cancer Cell
AU2005231692B2 (en) 2004-03-26 2011-01-27 Curis, Inc. RNA interference modulators of Hedgehog signaling and uses thereof
CA2580189C (en) 2004-09-29 2013-05-21 Children's Memorial Hospital Sirna-mediated gene silencing of alpha synuclein
WO2006054625A1 (ja) * 2004-11-19 2006-05-26 Genecare Research Institute Co., Ltd. 癌細胞特異的細胞増殖抑制剤

Also Published As

Publication number Publication date
ITRM20090328A1 (it) 2010-12-26
WO2010150159A1 (en) 2010-12-29

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