IT1392238B1 - USE OF CASPASI-3 FOR ALZHEIMER DISEASE - Google Patents
USE OF CASPASI-3 FOR ALZHEIMER DISEASEInfo
- Publication number
- IT1392238B1 IT1392238B1 ITRM2008A000641A ITRM20080641A IT1392238B1 IT 1392238 B1 IT1392238 B1 IT 1392238B1 IT RM2008A000641 A ITRM2008A000641 A IT RM2008A000641A IT RM20080641 A ITRM20080641 A IT RM20080641A IT 1392238 B1 IT1392238 B1 IT 1392238B1
- Authority
- IT
- Italy
- Prior art keywords
- caspasi
- alzheimer disease
- alzheimer
- disease
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM2008A000641A IT1392238B1 (en) | 2008-12-02 | 2008-12-02 | USE OF CASPASI-3 FOR ALZHEIMER DISEASE |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM2008A000641A IT1392238B1 (en) | 2008-12-02 | 2008-12-02 | USE OF CASPASI-3 FOR ALZHEIMER DISEASE |
Publications (2)
Publication Number | Publication Date |
---|---|
ITRM20080641A1 ITRM20080641A1 (en) | 2010-06-03 |
IT1392238B1 true IT1392238B1 (en) | 2012-02-22 |
Family
ID=41182632
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITRM2008A000641A IT1392238B1 (en) | 2008-12-02 | 2008-12-02 | USE OF CASPASI-3 FOR ALZHEIMER DISEASE |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1392238B1 (en) |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000063250A1 (en) * | 1999-04-15 | 2000-10-26 | Merck Frosst Canada & Co. | Antibodies that recognize app cleaved by caspases and methods of use |
CA2386411A1 (en) * | 1999-10-13 | 2001-04-19 | Merck Frosst Canada & Co. | Nicotinyl aspartyl ketones as inhibitors of caspase-3 |
AU2002215766A1 (en) * | 2000-12-15 | 2002-06-24 | Merck Frosst Canada And Co. | Gamma-ketoacid dipeptide derivatives as inhibitors of caspase-3 |
WO2002066050A1 (en) * | 2001-02-23 | 2002-08-29 | Takeda Chemical Industries, Ltd. | Casoase 3 inhibitors |
US8013014B2 (en) * | 2002-07-05 | 2011-09-06 | Georgia Tech Research Corporation | Aza-peptide epoxides |
JP2006522122A (en) * | 2003-03-05 | 2006-09-28 | インネクサス バイオテクノロジー インコーポレイテッド | Transmembrane antibody-induced apoptosis inhibition |
US7326540B2 (en) * | 2003-03-14 | 2008-02-05 | The General Hospital Corporation | Methods for identifying compounds that modulate stabilization of secretase-associated proteins |
ES2367311T3 (en) * | 2004-04-15 | 2011-11-02 | University Of Florida Research Foundation, Inc. | MAP-2 PROTEOLYTIC DEGRADATION PRODUCTS AS DIAGNOSTIC BIOMARCATORS FOR NEURAL INJURIES. |
-
2008
- 2008-12-02 IT ITRM2008A000641A patent/IT1392238B1/en active
Also Published As
Publication number | Publication date |
---|---|
ITRM20080641A1 (en) | 2010-06-03 |
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