IT1318618B1 - Microsfere bioadesive a rilascio rapido per la somministrazionesublinguale di principi attivi. - Google Patents

Microsfere bioadesive a rilascio rapido per la somministrazionesublinguale di principi attivi.

Info

Publication number
IT1318618B1
IT1318618B1 IT2000MI001548A ITMI20001548A IT1318618B1 IT 1318618 B1 IT1318618 B1 IT 1318618B1 IT 2000MI001548 A IT2000MI001548 A IT 2000MI001548A IT MI20001548 A ITMI20001548 A IT MI20001548A IT 1318618 B1 IT1318618 B1 IT 1318618B1
Authority
IT
Italy
Prior art keywords
active ingredients
quick release
sublingual administration
bioadhesive microspheres
release bioadhesive
Prior art date
Application number
IT2000MI001548A
Other languages
English (en)
Inventor
Francesco Roversi
Francesco Cilurzo
Original Assignee
A C R Applied Coating Res S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A C R Applied Coating Res S A filed Critical A C R Applied Coating Res S A
Priority to IT2000MI001548A priority Critical patent/IT1318618B1/it
Publication of ITMI20001548A0 publication Critical patent/ITMI20001548A0/it
Priority to EP01945570A priority patent/EP1301174A1/en
Priority to AU2001267782A priority patent/AU2001267782A1/en
Priority to PCT/IB2001/001243 priority patent/WO2002003955A1/en
Publication of ITMI20001548A1 publication Critical patent/ITMI20001548A1/it
Application granted granted Critical
Publication of IT1318618B1 publication Critical patent/IT1318618B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT2000MI001548A 2000-07-10 2000-07-10 Microsfere bioadesive a rilascio rapido per la somministrazionesublinguale di principi attivi. IT1318618B1 (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT2000MI001548A IT1318618B1 (it) 2000-07-10 2000-07-10 Microsfere bioadesive a rilascio rapido per la somministrazionesublinguale di principi attivi.
EP01945570A EP1301174A1 (en) 2000-07-10 2001-07-09 Fast release bioadhesive microspheres for the sublingual administration of proximate principles
AU2001267782A AU2001267782A1 (en) 2000-07-10 2001-07-09 Fast release bioadhesive microspheres for the sublingual administration of proximate principles
PCT/IB2001/001243 WO2002003955A1 (en) 2000-07-10 2001-07-09 Fast release bioadhesive microspheres for the sublingual administration of proximate principles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000MI001548A IT1318618B1 (it) 2000-07-10 2000-07-10 Microsfere bioadesive a rilascio rapido per la somministrazionesublinguale di principi attivi.

Publications (3)

Publication Number Publication Date
ITMI20001548A0 ITMI20001548A0 (it) 2000-07-10
ITMI20001548A1 ITMI20001548A1 (it) 2002-01-10
IT1318618B1 true IT1318618B1 (it) 2003-08-27

Family

ID=11445441

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2000MI001548A IT1318618B1 (it) 2000-07-10 2000-07-10 Microsfere bioadesive a rilascio rapido per la somministrazionesublinguale di principi attivi.

Country Status (4)

Country Link
EP (1) EP1301174A1 (it)
AU (1) AU2001267782A1 (it)
IT (1) IT1318618B1 (it)
WO (1) WO2002003955A1 (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US6887493B2 (en) * 2000-10-25 2005-05-03 Adi Shefer Multi component controlled release system for oral care, food products, nutraceutical, and beverages
DE10244504A1 (de) * 2002-09-25 2004-04-08 Capsulution Nanoscience Ag Schnellfreisetzende Darreichungsform mit schwerlöslichem Wirkstoff
DE10332160A1 (de) 2003-07-15 2005-02-03 Röhm GmbH & Co. KG Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Peptid- oder Protein-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
WO2005018600A2 (en) * 2003-08-22 2005-03-03 Cube Medical A/S Method of treating a patient suffering from a solid tumour
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
EP1744760B1 (en) * 2004-04-22 2015-01-07 AcuCort AB Pharmaceutical compositions for acute glucocorticoid therapy
GB0613925D0 (en) 2006-07-13 2006-08-23 Unilever Plc Improvements relating to nanodispersions
CZ308594B6 (cs) * 2014-09-29 2020-12-23 VÝZKUMNÝ ÚSTAV VETERINÁRNÍHO LÉKAŘSTVÍ, v.v.i. Mukoadhezivní nosiče částic, způsob přípravy a použití
ITUB20153446A1 (it) * 2015-09-07 2017-03-07 Pharmafilm Srl Film orodispersibili a rapida disgregazione per uso terapeutico o alimentare

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1366002A (fr) * 1965-05-14 1964-07-10 Lansing Bagnall Ltd Perfectionnements concernant des chariots industriels
FR2621483B1 (fr) * 1987-10-08 1991-09-20 Medibrevex Nouvelles formes galeniques de corticoides pour administration par voie per- et sublinguale et leur procede de preparation
US5077051A (en) * 1990-04-10 1991-12-31 Warner-Lambert Company Sustained release of active agents from bioadhesive microcapsules
GB9009390D0 (en) * 1990-04-26 1990-06-20 Smith Kline French Lab Pharmaceutical compositions
JPH04230625A (ja) * 1990-12-27 1992-08-19 Standard Chem & Pharmaceut Corp Ltd 噴霧乾燥したジクロフェナクナトリウムを含み腸溶性の被覆を有するマイクロカプセルからなる微分散した錠剤組成物の製造方法
DE19617716A1 (de) * 1996-05-03 1997-11-06 Basf Ag In wäßriger Lösung redispergierbare Polymerpulver
GB9700624D0 (en) * 1997-01-14 1997-03-05 Danbiosyst Uk Drug delivery composition
DE19704293A1 (de) * 1997-02-05 1998-08-06 Basf Ag Zahnprothesenhaftmittel
SE9803239D0 (sv) * 1998-09-24 1998-09-24 Diabact Ab Composition for the treatment of acute pain

Also Published As

Publication number Publication date
EP1301174A1 (en) 2003-04-16
WO2002003955A1 (en) 2002-01-17
ITMI20001548A0 (it) 2000-07-10
AU2001267782A1 (en) 2002-01-21
ITMI20001548A1 (it) 2002-01-10

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