IT1299582B1 - Procedimento per la preparazione dell'acido 13-cis-retinoico - Google Patents

Procedimento per la preparazione dell'acido 13-cis-retinoico

Info

Publication number
IT1299582B1
IT1299582B1 IT98MI001093A ITMI981093A IT1299582B1 IT 1299582 B1 IT1299582 B1 IT 1299582B1 IT 98MI001093 A IT98MI001093 A IT 98MI001093A IT MI981093 A ITMI981093 A IT MI981093A IT 1299582 B1 IT1299582 B1 IT 1299582B1
Authority
IT
Italy
Prior art keywords
cis
retinoic acid
procedure
preparation
vinyl
Prior art date
Application number
IT98MI001093A
Other languages
English (en)
Inventor
Grato Angelo Magnone
Original Assignee
Lab Mag Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lab Mag Spa filed Critical Lab Mag Spa
Priority to IT98MI001093A priority Critical patent/IT1299582B1/it
Priority to CA2272439A priority patent/CA2272439C/en
Priority to US09/313,028 priority patent/US6177579B1/en
Priority to EP99109784A priority patent/EP0959069B1/en
Priority to ES99109784T priority patent/ES2185263T3/es
Priority to DK99109784T priority patent/DK0959069T3/da
Priority to ZA9903395A priority patent/ZA993395B/xx
Priority to DE69903498T priority patent/DE69903498T2/de
Priority to AT99109784T priority patent/ATE226190T1/de
Priority to PL333200A priority patent/PL192958B1/pl
Priority to IN566MA1999 priority patent/IN188476B/en
Priority to JP13890999A priority patent/JP4418048B2/ja
Priority to SG9902501A priority patent/SG80628A1/en
Priority to BRPI9901551-0A priority patent/BR9901551B1/pt
Priority to HU9901651A priority patent/HU229518B1/hu
Priority to NO992396A priority patent/NO317759B1/no
Publication of ITMI981093A1 publication Critical patent/ITMI981093A1/it
Application granted granted Critical
Publication of IT1299582B1 publication Critical patent/IT1299582B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
IT98MI001093A 1998-05-19 1998-05-19 Procedimento per la preparazione dell'acido 13-cis-retinoico IT1299582B1 (it)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IT98MI001093A IT1299582B1 (it) 1998-05-19 1998-05-19 Procedimento per la preparazione dell'acido 13-cis-retinoico
US09/313,028 US6177579B1 (en) 1998-05-19 1999-05-17 Process for the preparation of 13-cis-retinoic acid
CA2272439A CA2272439C (en) 1998-05-19 1999-05-17 A process for the preparation of 13-cis-retinoic acid
IN566MA1999 IN188476B (it) 1998-05-19 1999-05-18
DK99109784T DK0959069T3 (da) 1998-05-19 1999-05-18 Fremgangsmåde til fremstilling af 13-cis-retinsyre
ZA9903395A ZA993395B (en) 1998-05-19 1999-05-18 A process for the preparation of 13-cis-retinoic acid.
DE69903498T DE69903498T2 (de) 1998-05-19 1999-05-18 Verfahren zur Herstellung von 13-cis-Retinsäure
AT99109784T ATE226190T1 (de) 1998-05-19 1999-05-18 Verfahren zur herstellung von 13-cis-retinsäure
EP99109784A EP0959069B1 (en) 1998-05-19 1999-05-18 A process for the preparation of 13-CIS-retinoic acid
ES99109784T ES2185263T3 (es) 1998-05-19 1999-05-18 Procedimiento para la preparacion de acido 13-cis-retinoico'.
PL333200A PL192958B1 (pl) 1998-05-19 1999-05-18 Sposób wytwarzania kwasu 13-cis-retynowego
JP13890999A JP4418048B2 (ja) 1998-05-19 1999-05-19 １３−シス−レチノイン酸の製造方法
SG9902501A SG80628A1 (en) 1998-05-19 1999-05-19 A process for the preparation of 13-cis-retinoic acid
BRPI9901551-0A BR9901551B1 (pt) 1998-05-19 1999-05-19 processo para preparação de ácido 13-cis -retinóico.
HU9901651A HU229518B1 (hu) 1998-05-19 1999-05-19 Eljárás 13-cisz-retinsav elõállítására
NO992396A NO317759B1 (no) 1998-05-19 1999-05-19 Fremgangsmåte ved fremstilling av 13-cis-retinsyre

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT98MI001093A IT1299582B1 (it) 1998-05-19 1998-05-19 Procedimento per la preparazione dell'acido 13-cis-retinoico

Publications (2)

Publication Number Publication Date
ITMI981093A1 ITMI981093A1 (it) 1999-11-19
IT1299582B1 true IT1299582B1 (it) 2000-03-16

Family

ID=11380052

Family Applications (1)

Application Number Title Priority Date Filing Date
IT98MI001093A IT1299582B1 (it) 1998-05-19 1998-05-19 Procedimento per la preparazione dell'acido 13-cis-retinoico

Country Status (16)

Country Link
US (1) US6177579B1 (it)
EP (1) EP0959069B1 (it)
JP (1) JP4418048B2 (it)
AT (1) ATE226190T1 (it)
BR (1) BR9901551B1 (it)
CA (1) CA2272439C (it)
DE (1) DE69903498T2 (it)
DK (1) DK0959069T3 (it)
ES (1) ES2185263T3 (it)
HU (1) HU229518B1 (it)
IN (1) IN188476B (it)
IT (1) IT1299582B1 (it)
NO (1) NO317759B1 (it)
PL (1) PL192958B1 (it)
SG (1) SG80628A1 (it)
ZA (1) ZA993395B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008102375A2 (en) * 2007-02-20 2008-08-28 Ipca Laboratories Limited A process for preparation of highly pure isotretinoin
CN104447459A (zh) * 2014-11-28 2015-03-25 重庆华邦制药有限公司 异维a酸的新晶型及其制备方法与应用
CN111454141A (zh) * 2020-04-26 2020-07-28 上海新华联制药有限公司 一种异维a酸缩合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3200231A1 (de) 1982-01-07 1983-07-21 Basf Ag, 6700 Ludwigshafen (alpha)-pyrone und verfahren zur herstellung von polyencarbonsaeuren
DE4313089A1 (de) 1993-04-22 1994-10-27 Basf Ag Verfahren zur Herstellung von 13-(Z)-Retinsäure
IT1289528B1 (it) 1996-12-27 1998-10-15 Lab Mag Spa Procedimento per la preparazione dell'acido 13,cis-retinoico

Also Published As

Publication number Publication date
ZA993395B (en) 1999-11-18
DE69903498T2 (de) 2003-02-27
PL333200A1 (en) 1999-11-22
ATE226190T1 (de) 2002-11-15
EP0959069B1 (en) 2002-10-16
HUP9901651A3 (en) 2000-06-28
EP0959069A1 (en) 1999-11-24
NO317759B1 (no) 2004-12-13
IN188476B (it) 2002-09-28
DE69903498D1 (de) 2002-11-21
HU9901651D0 (en) 1999-07-28
JP2000034275A (ja) 2000-02-02
CA2272439C (en) 2010-05-11
CA2272439A1 (en) 1999-11-19
NO992396D0 (no) 1999-05-19
US6177579B1 (en) 2001-01-23
HU229518B1 (hu) 2014-01-28
DK0959069T3 (da) 2003-02-24
NO992396L (no) 1999-11-22
PL192958B1 (pl) 2006-12-29
JP4418048B2 (ja) 2010-02-17
SG80628A1 (en) 2001-05-22
ES2185263T3 (es) 2003-04-16
ITMI981093A1 (it) 1999-11-19
BR9901551B1 (pt) 2010-10-19
HUP9901651A2 (hu) 1999-12-28
BR9901551A (pt) 2000-05-30

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Legal Events

Date Code Title Description
0001 Granted