IT1298442B1 - Composizioni orali a basso dosaggio di proteine citotossiche - Google Patents

Composizioni orali a basso dosaggio di proteine citotossiche

Info

Publication number
IT1298442B1
IT1298442B1 IT98MI000356A ITMI980356A IT1298442B1 IT 1298442 B1 IT1298442 B1 IT 1298442B1 IT 98MI000356 A IT98MI000356 A IT 98MI000356A IT MI980356 A ITMI980356 A IT MI980356A IT 1298442 B1 IT1298442 B1 IT 1298442B1
Authority
IT
Italy
Prior art keywords
oral compositions
low dosage
cytotoxic proteins
dosage oral
proteins
Prior art date
Application number
IT98MI000356A
Other languages
English (en)
Inventor
Alberto Bartorelli
Cesare Santi
Original Assignee
Zetesis Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to IT98MI000356A priority Critical patent/IT1298442B1/it
Application filed by Zetesis Spa filed Critical Zetesis Spa
Priority to PCT/EP1999/001068 priority patent/WO1999043340A1/en
Priority to JP2000533136A priority patent/JP2002504517A/ja
Priority to DK99906246T priority patent/DK1061938T3/da
Priority to EP99906246A priority patent/EP1061938B1/en
Priority to ES99906246T priority patent/ES2165727T3/es
Priority to AU26244/99A priority patent/AU2624499A/en
Priority to CA002321717A priority patent/CA2321717A1/en
Priority to DE69900466T priority patent/DE69900466T2/de
Priority to AT99906246T priority patent/ATE208627T1/de
Priority to PT99906246T priority patent/PT1061938E/pt
Publication of ITMI980356A1 publication Critical patent/ITMI980356A1/it
Application granted granted Critical
Publication of IT1298442B1 publication Critical patent/IT1298442B1/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
IT98MI000356A 1998-02-24 1998-02-24 Composizioni orali a basso dosaggio di proteine citotossiche IT1298442B1 (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT98MI000356A IT1298442B1 (it) 1998-02-24 1998-02-24 Composizioni orali a basso dosaggio di proteine citotossiche
JP2000533136A JP2002504517A (ja) 1998-02-24 1999-02-18 低用量の細胞傷害性タンパク質の経口組成物
DK99906246T DK1061938T3 (da) 1998-02-24 1999-02-18 Orale sammensætninger med cytotoksiske proteiner i lav dosis
EP99906246A EP1061938B1 (en) 1998-02-24 1999-02-18 Oral compositions at low dosage of cytotoxic proteins
PCT/EP1999/001068 WO1999043340A1 (en) 1998-02-24 1999-02-18 Oral compositions at low dosage of cytotoxic proteins
ES99906246T ES2165727T3 (es) 1998-02-24 1999-02-18 Composiciones de administracion por via oral con baja dosificacion de proteinas citotoxicas.
AU26244/99A AU2624499A (en) 1998-02-24 1999-02-18 Oral compositions at low dosage of cytotoxic proteins
CA002321717A CA2321717A1 (en) 1998-02-24 1999-02-18 Oral compositions at low dosage of cytotoxic proteins
DE69900466T DE69900466T2 (de) 1998-02-24 1999-02-18 Orale zusammensetzungen mit niedrigdosierten zytotoxischen proteinen
AT99906246T ATE208627T1 (de) 1998-02-24 1999-02-18 Orale zusammensetzungen mit niedrigdosierten zytotoxischen proteinen
PT99906246T PT1061938E (pt) 1998-02-24 1999-02-18 Composicoes para administracao por via oral com baixo teor de proteinas citotoxicas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT98MI000356A IT1298442B1 (it) 1998-02-24 1998-02-24 Composizioni orali a basso dosaggio di proteine citotossiche

Publications (2)

Publication Number Publication Date
ITMI980356A1 ITMI980356A1 (it) 1999-08-24
IT1298442B1 true IT1298442B1 (it) 2000-01-10

Family

ID=11379051

Family Applications (1)

Application Number Title Priority Date Filing Date
IT98MI000356A IT1298442B1 (it) 1998-02-24 1998-02-24 Composizioni orali a basso dosaggio di proteine citotossiche

Country Status (11)

Country Link
EP (1) EP1061938B1 (it)
JP (1) JP2002504517A (it)
AT (1) ATE208627T1 (it)
AU (1) AU2624499A (it)
CA (1) CA2321717A1 (it)
DE (1) DE69900466T2 (it)
DK (1) DK1061938T3 (it)
ES (1) ES2165727T3 (it)
IT (1) IT1298442B1 (it)
PT (1) PT1061938E (it)
WO (1) WO1999043340A1 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI991384A1 (it) * 1999-06-22 2000-12-22 Zetesis Spa Uso della proteina uk 114 per inibire il rigetto dei trapianti d'organo
ITMI20010762A1 (it) * 2001-04-10 2002-10-10 Zetesis Spa Uso della proteina uk114 o di suoi frammenti per il trattamento e la prevenzione dello shock endotossico
ITMI20021205A1 (it) * 2002-06-04 2003-12-04 Pharmaproducts Uk Ltd Uso di proteine per il trattamento della leishmaniosi
FR2842420B1 (fr) * 2002-07-16 2006-07-14 Rocher Yves Biolog Vegetale Composition cosmetique comprenant de l'ubiquitine
IT201600127428A1 (it) 2016-12-16 2018-06-16 Cusani Alberto Bartorelli Nuova proteina ricombinante uk 114 in forma stabile polimerica per uso nella terapia, nella diagnostica e nella prevenzione di neoplasie maligne

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE628373A (it) * 1962-02-23 1900-01-01 Phygiene
IT1244879B (it) * 1990-12-11 1994-09-12 Alberto Bartorelli Estratti da tessuti animali, utili in terapia e in diagnostica.
IT1270618B (it) * 1994-07-14 1997-05-07 Zetesis Spa Proteine ad attivita' antitumorale

Also Published As

Publication number Publication date
DE69900466D1 (de) 2001-12-20
EP1061938A1 (en) 2000-12-27
DE69900466T2 (de) 2002-04-04
WO1999043340A1 (en) 1999-09-02
AU2624499A (en) 1999-09-15
PT1061938E (pt) 2002-04-29
EP1061938B1 (en) 2001-11-14
CA2321717A1 (en) 1999-09-02
DK1061938T3 (da) 2002-02-11
ATE208627T1 (de) 2001-11-15
ES2165727T3 (es) 2002-03-16
JP2002504517A (ja) 2002-02-12
ITMI980356A1 (it) 1999-08-24

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Legal Events

Date Code Title Description
0001 Granted