IT1277048B1 - Procedimento per la preparazione di cefalosporine attraverso ciclizzazione riduttiva dicarbonilica per trattamento con - Google Patents
Procedimento per la preparazione di cefalosporine attraverso ciclizzazione riduttiva dicarbonilica per trattamento conInfo
- Publication number
- IT1277048B1 IT1277048B1 IT95MI002571A ITMI952571A IT1277048B1 IT 1277048 B1 IT1277048 B1 IT 1277048B1 IT 95MI002571 A IT95MI002571 A IT 95MI002571A IT MI952571 A ITMI952571 A IT MI952571A IT 1277048 B1 IT1277048 B1 IT 1277048B1
- Authority
- IT
- Italy
- Prior art keywords
- reducive
- dicarbonil
- cephalosporins
- cycling
- procedure
- Prior art date
Links
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title 1
- 230000001351 cycling effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95MI002571A IT1277048B1 (it) | 1995-12-06 | 1995-12-06 | Procedimento per la preparazione di cefalosporine attraverso ciclizzazione riduttiva dicarbonilica per trattamento con |
| PCT/EP1996/005449 WO1997020848A1 (en) | 1995-12-06 | 1996-12-05 | Process for the preparation of cephalosporins via reductive dicarbonyl cyclization induced by trialkyl phosphite of 4-thioazetidinone derivatives obtained from penicillins |
| AU11912/97A AU1191297A (en) | 1995-12-06 | 1996-12-05 | Process for the preparation of cephalosporins via reductive dicarbonyl cyclization induced by trialkyl phosphite of 4-thioazetidinone derivatives obtained from penicillins |
| EP96943044A EP0876377A1 (en) | 1995-12-06 | 1996-12-05 | Process for the preparation of cephalosporins via reductive dicarbonyl cyclization induced by trialkyl phosphite of 4-thioazetidinone derivatives obtained from penicillins |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95MI002571A IT1277048B1 (it) | 1995-12-06 | 1995-12-06 | Procedimento per la preparazione di cefalosporine attraverso ciclizzazione riduttiva dicarbonilica per trattamento con |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI952571A0 ITMI952571A0 (it) | 1995-12-06 |
| ITMI952571A1 ITMI952571A1 (it) | 1997-06-06 |
| IT1277048B1 true IT1277048B1 (it) | 1997-11-04 |
Family
ID=11372675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT95MI002571A IT1277048B1 (it) | 1995-12-06 | 1995-12-06 | Procedimento per la preparazione di cefalosporine attraverso ciclizzazione riduttiva dicarbonilica per trattamento con |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0876377A1 (it) |
| AU (1) | AU1191297A (it) |
| IT (1) | IT1277048B1 (it) |
| WO (1) | WO1997020848A1 (it) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114728008A (zh) * | 2019-08-29 | 2022-07-08 | 加利福尼亚大学董事会 | 鉴定β-内酰胺酶的化合物及其使用方法 |
| CN111763221A (zh) * | 2020-07-31 | 2020-10-13 | 重庆医药高等专科学校 | 一种头孢维星中间体及其制备方法 |
| CN111892612A (zh) * | 2020-07-31 | 2020-11-06 | 重庆医药高等专科学校 | 一种以青霉素钾盐为原料制备头孢维星的中间体异构化物及其制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1136132A (en) * | 1975-02-17 | 1982-11-23 | Teruji Tsuji | Cyclization to form cephem ring and intermediates therefor |
| GB8819104D0 (en) * | 1988-08-11 | 1988-09-14 | Beecham Group Plc | Novel compounds |
| ES2121745T3 (es) * | 1989-03-30 | 1998-12-16 | Pfizer | Cefalosporinas y sus homologos, procedimiento para su preparacion y composiciones farmaceuticas. |
-
1995
- 1995-12-06 IT IT95MI002571A patent/IT1277048B1/it active IP Right Grant
-
1996
- 1996-12-05 WO PCT/EP1996/005449 patent/WO1997020848A1/en not_active Application Discontinuation
- 1996-12-05 EP EP96943044A patent/EP0876377A1/en not_active Withdrawn
- 1996-12-05 AU AU11912/97A patent/AU1191297A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU1191297A (en) | 1997-06-27 |
| ITMI952571A1 (it) | 1997-06-06 |
| WO1997020848A1 (en) | 1997-06-12 |
| ITMI952571A0 (it) | 1995-12-06 |
| EP0876377A1 (en) | 1998-11-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |