IT1270239B - Composizione farmaceutica solida contenente acido (s)-2-(4- isobutilfenil) propionico come principio attivo - Google Patents

Composizione farmaceutica solida contenente acido (s)-2-(4- isobutilfenil) propionico come principio attivo

Info

Publication number
IT1270239B
IT1270239B ITMI941262A ITMI941262A IT1270239B IT 1270239 B IT1270239 B IT 1270239B IT MI941262 A ITMI941262 A IT MI941262A IT MI941262 A ITMI941262 A IT MI941262A IT 1270239 B IT1270239 B IT 1270239B
Authority
IT
Italy
Prior art keywords
isobutylphenyl
active ingredient
pharmaceutical composition
composition containing
propionic
Prior art date
Application number
ITMI941262A
Other languages
English (en)
Inventor
Federico Stroppolo
Daniele Bonadeo
Alberto Pagano
Annibale Gazzaniga
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of ITMI941262A0 publication Critical patent/ITMI941262A0/it
Priority to ITMI941262A priority Critical patent/IT1270239B/it
Priority to AU26167/95A priority patent/AU696778B2/en
Priority to CZ963662A priority patent/CZ285199B6/cs
Priority to DE69518237T priority patent/DE69518237T2/de
Priority to JP50154196A priority patent/JP3836507B2/ja
Priority to EP95920900A priority patent/EP0758889B1/en
Priority to US08/750,201 priority patent/US5869102A/en
Priority to PCT/EP1995/002010 priority patent/WO1995035104A1/en
Priority to DK95920900T priority patent/DK0758889T3/da
Priority to CA002191855A priority patent/CA2191855C/en
Priority to HU9603463A priority patent/HU219246B/hu
Priority to NZ287445A priority patent/NZ287445A/en
Priority to AT95920900T priority patent/ATE195073T1/de
Priority to RU97100851/14A priority patent/RU2168980C2/ru
Priority to PT95920900T priority patent/PT758889E/pt
Priority to ES95920900T priority patent/ES2149990T3/es
Publication of ITMI941262A1 publication Critical patent/ITMI941262A1/it
Application granted granted Critical
Publication of IT1270239B publication Critical patent/IT1270239B/it
Priority to GR20000402345T priority patent/GR3034655T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Viene descritta una composizione farmaceutica solida contenente (S)-2-(4-isobutilfenil) propionico come principio attivo adatta per la preparazione di forme farmaceutiche in compresse, bustine e capsule.
ITMI941262A 1994-06-17 1994-06-17 Composizione farmaceutica solida contenente acido (s)-2-(4- isobutilfenil) propionico come principio attivo IT1270239B (it)

Priority Applications (17)

Application Number Priority Date Filing Date Title
ITMI941262A IT1270239B (it) 1994-06-17 1994-06-17 Composizione farmaceutica solida contenente acido (s)-2-(4- isobutilfenil) propionico come principio attivo
DK95920900T DK0758889T3 (da) 1994-06-17 1995-05-26 Faste,farmaceutiske præparater, der indeholder (S)-2-(4-isobutylphenyl)propionsyre som aktiv bestanddel og mikrokrystallins
HU9603463A HU219246B (en) 1994-06-17 1995-05-26 Solid pharmaceutical compositions containing (s)-2-(4-isobutylphenyl) propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients and pharmaceutical forms prepared by using these compositions
DE69518237T DE69518237T2 (de) 1994-06-17 1995-05-26 Feste pharmazeutische zubereitung mit (s)-2-(4-isobutylphenyl)propionsäure als wirkstoff und mikrokristalliner cellulose und kolloidalem silica als hilfstoff
JP50154196A JP3836507B2 (ja) 1994-06-17 1995-05-26 （ｓ）−２−（４−イソブチルフェニル）プロピオン酸を活性成分とし、微結晶セルロースおよびコロイダルシリカを賦形剤とする固形医薬組成物
EP95920900A EP0758889B1 (en) 1994-06-17 1995-05-26 Solid pharmaceutical compositions containing (s)-2-(4-isobutylphenyl)propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients
US08/750,201 US5869102A (en) 1994-06-17 1995-05-26 Solid pharmaceutical compositions containing (S)-2-(4-isobutylphenyl) propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients
PCT/EP1995/002010 WO1995035104A1 (en) 1994-06-17 1995-05-26 Solid pharmaceutical compositions containing (s)-2-(4-isobutylphenyl)propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients
AU26167/95A AU696778B2 (en) 1994-06-17 1995-05-26 Solid pharmaceutical compositions containing (S)-2-(4-isobutylphenyl)propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients
CA002191855A CA2191855C (en) 1994-06-17 1995-05-26 Solid pharmaceutical compositions containing (s)-2-(4-isobutylphenyl)propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients
CZ963662A CZ285199B6 (cs) 1994-06-17 1995-05-26 Pevný farmaceutický prostředek
NZ287445A NZ287445A (en) 1994-06-17 1995-05-26 Pharmaceutical composition comprising (s)-2-(4-isobutylphenyl)propionic acid and microcrystalline cellulose and colloidal silica excipients
AT95920900T ATE195073T1 (de) 1994-06-17 1995-05-26 Feste pharmazeutische zubereitung mit (s)-2-(4- isobutylphenyl)propionsäure als wirkstoff und mikrokristalliner cellulose und kolloidalem silica als hilfstoff
RU97100851/14A RU2168980C2 (ru) 1994-06-17 1995-05-26 Твердые фармацевтические композиции, содержащие (s)-2-(4-изобутилфенил)-пропионовую кислоту в качестве активного ингредиента и микрокристаллическую целлюлозу и коллоидный оксид кремния в качестве эксципиентов
PT95920900T PT758889E (pt) 1994-06-17 1995-05-26 Composicoes farmaceuticas solidas contendo um principio activo a base de acido (s)-2-(4-isobutilfenil) propionico e celulose microcristalina e silica coloidal como excipientes
ES95920900T ES2149990T3 (es) 1994-06-17 1995-05-26 Composiciones farmaceuticas solidas que contienen ingrediente activo de acido (s)-2-(4-isobutilfenil)propionico y celulosa microcristalina y silice coloidal como excipientes.
GR20000402345T GR3034655T3 (en) 1994-06-17 2000-10-23 Solid pharmaceutical compositions containing (s)-2-(4-isobutylphenyl)propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI941262A IT1270239B (it) 1994-06-17 1994-06-17 Composizione farmaceutica solida contenente acido (s)-2-(4- isobutilfenil) propionico come principio attivo

Publications (3)

Publication Number Publication Date
ITMI941262A0 ITMI941262A0 (it) 1994-06-17
ITMI941262A1 ITMI941262A1 (it) 1995-12-17
IT1270239B true IT1270239B (it) 1997-04-29

Family

ID=11369126

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI941262A IT1270239B (it) 1994-06-17 1994-06-17 Composizione farmaceutica solida contenente acido (s)-2-(4- isobutilfenil) propionico come principio attivo

Country Status (16)

Country Link
US (1) US5869102A (it)
EP (1) EP0758889B1 (it)
JP (1) JP3836507B2 (it)
AT (1) ATE195073T1 (it)
AU (1) AU696778B2 (it)
CZ (1) CZ285199B6 (it)
DE (1) DE69518237T2 (it)
DK (1) DK0758889T3 (it)
ES (1) ES2149990T3 (it)
GR (1) GR3034655T3 (it)
HU (1) HU219246B (it)
IT (1) IT1270239B (it)
NZ (1) NZ287445A (it)
PT (1) PT758889E (it)
RU (1) RU2168980C2 (it)
WO (1) WO1995035104A1 (it)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395303B1 (en) 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6471994B1 (en) 1995-01-09 2002-10-29 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US6936277B2 (en) 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
US5733578A (en) 1995-11-15 1998-03-31 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US6852336B2 (en) 1995-11-15 2005-02-08 J. Rettenmaier & Soehne Gmbh + Co. Kg Directly compressible high load acetaminophen formulations
US6391337B2 (en) 1995-11-15 2002-05-21 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
US5990176A (en) * 1997-01-27 1999-11-23 Abbott Laboratories Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid
DE10003757A1 (de) * 2000-01-28 2001-08-02 Knoll Ag Ibuprofen-Wirkstoffzubereitung
KR100700721B1 (ko) * 2000-09-08 2007-03-27 지상철 안정성 및 용출율이 향상된 ｓ(+)-이부프로펜의 정제
US6926938B2 (en) * 2001-01-10 2005-08-09 Suheung Capsule Co., Ltd. Hardshell gelatin capsule reducing the static electricity and enhancing the lubrication of film
EP1379226A2 (en) * 2001-04-10 2004-01-14 Zagros Pharma Inc. Animal model for evaluating analgesics
US6551615B1 (en) 2001-10-18 2003-04-22 M/S. Strides Arcolab Limited Dexibuprofen-containing soft gelatin capsules and process for preparing the same
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
EP1902708A1 (de) * 2006-09-25 2008-03-26 Losan Pharma GmbH Wirkstoff enthaltende stabilisierte feste Arzneimittelformen und Verfahren zu ihrer Herstellung
WO2013154512A1 (en) * 2012-04-13 2013-10-17 Mahmut Bilgic Pharmaceutical formulations comprising dexibuprofen
JP2015537029A (ja) 2012-11-14 2015-12-24 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ 生物学的に活性な物質及び不規則性無機酸化物を含有する組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
DK62184D0 (da) * 1984-02-10 1984-02-10 Benzon As Alfred Diffusionsovertrukket polydepotpraeparat
GB8521350D0 (en) * 1985-08-28 1985-10-02 Euro Celtique Sa Analgesic composition
GB8623557D0 (en) * 1986-10-01 1986-11-05 Boots Co Plc Therapeutic agents
EP0267321B1 (de) * 1986-11-14 1990-02-28 MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG Ibuprofen enthaltendes Arzneimittel
GB8629567D0 (en) * 1986-12-10 1987-01-21 Boots Co Plc Therapeutic agents
GB8905815D0 (en) * 1989-03-14 1989-04-26 Beecham Group Plc Medicament
US5164398A (en) * 1991-04-01 1992-11-17 Merck & Co., Inc. Ibuprofen-antitussive combinations
ES2148175T3 (es) * 1991-05-13 2000-10-16 Boots Co Plc Composicion farmaceutica que contiene una sal de ibuprofeno.
DK138592D0 (da) * 1992-11-17 1992-11-17 Nycomed Dak As Tabletter

Also Published As

Publication number Publication date
US5869102A (en) 1999-02-09
CZ366296A3 (en) 1997-11-12
ITMI941262A0 (it) 1994-06-17
EP0758889A1 (en) 1997-02-26
DK0758889T3 (da) 2000-11-27
HUT76325A (en) 1997-08-28
GR3034655T3 (en) 2001-01-31
DE69518237D1 (de) 2000-09-07
JP3836507B2 (ja) 2006-10-25
JPH10501537A (ja) 1998-02-10
HU9603463D0 (en) 1997-02-28
ES2149990T3 (es) 2000-11-16
HU219246B (en) 2001-03-28
DE69518237T2 (de) 2001-02-22
ITMI941262A1 (it) 1995-12-17
RU2168980C2 (ru) 2001-06-20
WO1995035104A1 (en) 1995-12-28
NZ287445A (en) 1998-05-27
CZ285199B6 (cs) 1999-06-16
EP0758889B1 (en) 2000-08-02
PT758889E (pt) 2000-12-29
AU696778B2 (en) 1998-09-17
ATE195073T1 (de) 2000-08-15
AU2616795A (en) 1996-01-15

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Legal Events

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970825