IT1265305B1 - Organometallic derivatives of S-acyl-2-(S)-(2-pyrrolidone- 5-(S)-carbonylamido)-3-mercapto propionic acids with selenium, process for their preparation and pharmaceutical compositions containing them - Google Patents
Organometallic derivatives of S-acyl-2-(S)-(2-pyrrolidone- 5-(S)-carbonylamido)-3-mercapto propionic acids with selenium, process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IT1265305B1 IT1265305B1 IT93MI002680A ITMI932680A IT1265305B1 IT 1265305 B1 IT1265305 B1 IT 1265305B1 IT 93MI002680 A IT93MI002680 A IT 93MI002680A IT MI932680 A ITMI932680 A IT MI932680A IT 1265305 B1 IT1265305 B1 IT 1265305B1
- Authority
- IT
- Italy
- Prior art keywords
- carbonylamido
- selenium
- pyrrolidone
- acyl
- preparation
- Prior art date
Links
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 125000002524 organometallic group Chemical group 0.000 title abstract 2
- 230000008569 process Effects 0.000 title abstract 2
- 235000019260 propionic acid Nutrition 0.000 title abstract 2
- 229910052711 selenium Inorganic materials 0.000 title abstract 2
- 239000011669 selenium Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000000509 infertility Diseases 0.000 abstract 1
- 230000036512 infertility Effects 0.000 abstract 1
- 231100000535 infertility Toxicity 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
This invention relates to organometallic derivatives of S- acyl-2-(S)-(2-pyrrolidone-5-(S)-carbonylamido)-3-mercapto propionic acids with selenium which are more potent than the corresponding free acids in the treatment of diseases of the central nervous system associated with phenomena of ageing and infertility, process for their preparation and therapeutic compositions containing them.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT93MI002680A IT1265305B1 (en) | 1993-12-21 | 1993-12-21 | Organometallic derivatives of S-acyl-2-(S)-(2-pyrrolidone- 5-(S)-carbonylamido)-3-mercapto propionic acids with selenium, process for their preparation and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT93MI002680A IT1265305B1 (en) | 1993-12-21 | 1993-12-21 | Organometallic derivatives of S-acyl-2-(S)-(2-pyrrolidone- 5-(S)-carbonylamido)-3-mercapto propionic acids with selenium, process for their preparation and pharmaceutical compositions containing them |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI932680A0 ITMI932680A0 (en) | 1993-12-21 |
| ITMI932680A1 ITMI932680A1 (en) | 1995-06-21 |
| IT1265305B1 true IT1265305B1 (en) | 1996-10-31 |
Family
ID=11367367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT93MI002680A IT1265305B1 (en) | 1993-12-21 | 1993-12-21 | Organometallic derivatives of S-acyl-2-(S)-(2-pyrrolidone- 5-(S)-carbonylamido)-3-mercapto propionic acids with selenium, process for their preparation and pharmaceutical compositions containing them |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1265305B1 (en) |
-
1993
- 1993-12-21 IT IT93MI002680A patent/IT1265305B1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI932680A1 (en) | 1995-06-21 |
| ITMI932680A0 (en) | 1993-12-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19961230 |