IT1264690B1 - Compositi oligomeri iodurati e composizioni diagnostiche contenenti gli stessi - Google Patents

Compositi oligomeri iodurati e composizioni diagnostiche contenenti gli stessi

Info

Publication number
IT1264690B1
IT1264690B1 IT93MI001479A ITMI931479A IT1264690B1 IT 1264690 B1 IT1264690 B1 IT 1264690B1 IT 93MI001479 A IT93MI001479 A IT 93MI001479A IT MI931479 A ITMI931479 A IT MI931479A IT 1264690 B1 IT1264690 B1 IT 1264690B1
Authority
IT
Italy
Prior art keywords
iodurated
same
compositions containing
diagnostic compositions
composites
Prior art date
Application number
IT93MI001479A
Other languages
English (en)
Inventor
Pier Lucio Anelli
Marino Brocchetta
Haen Christoph De
Ornella Gazzotti
Fulvio Uggeri
Sandra Verona
Massimo Visigalli
Original Assignee
Bracco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Spa filed Critical Bracco Spa
Publication of ITMI931479A0 publication Critical patent/ITMI931479A0/it
Priority to IT93MI001479A priority Critical patent/IT1264690B1/it
Priority to JP7503801A priority patent/JPH08512297A/ja
Priority to PCT/EP1994/002111 priority patent/WO1995001966A1/en
Priority to AU71251/94A priority patent/AU7125194A/en
Priority to EP94920471A priority patent/EP0707572A1/en
Priority to IL11024994A priority patent/IL110249A0/xx
Priority to ZA944923A priority patent/ZA944923B/xx
Priority to IS4189A priority patent/IS4189A/is
Publication of ITMI931479A1 publication Critical patent/ITMI931479A1/it
Application granted granted Critical
Publication of IT1264690B1 publication Critical patent/IT1264690B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/50—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0442—Polymeric X-ray contrast-enhancing agent comprising a halogenated group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invenzione si riferisce ad agenti di contrasto particolarmente utili per l'indagine diagnostica roentgenografica del distretto vascolare del corpo umano ed animale.
IT93MI001479A 1993-07-08 1993-07-08 Compositi oligomeri iodurati e composizioni diagnostiche contenenti gli stessi IT1264690B1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT93MI001479A IT1264690B1 (it) 1993-07-08 1993-07-08 Compositi oligomeri iodurati e composizioni diagnostiche contenenti gli stessi
EP94920471A EP0707572A1 (en) 1993-07-08 1994-06-29 Iodinated oligomeric compounds and diagnostic compositions containing the same
PCT/EP1994/002111 WO1995001966A1 (en) 1993-07-08 1994-06-29 Iodinated oligomeric compounds and diagnostic compositions containing the same
AU71251/94A AU7125194A (en) 1993-07-08 1994-06-29 Iodinated oligomeric compounds and diagnostic compositions containing the same
JP7503801A JPH08512297A (ja) 1993-07-08 1994-06-29 ヨウ素化オリゴマー化合物およびこれを含む診断用組成物
IL11024994A IL110249A0 (en) 1993-07-08 1994-07-07 Iodinated oligomeric compounds and diagnostic compositions containing the same
ZA944923A ZA944923B (en) 1993-07-08 1994-07-07 Iodinated oligomeric compounds and diagnostic compositions containing the same
IS4189A IS4189A (is) 1993-07-08 1994-07-07 Joðuð fáliða efnasambönd og efnasambönd til greiningar sem innihalda þau

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001479A IT1264690B1 (it) 1993-07-08 1993-07-08 Compositi oligomeri iodurati e composizioni diagnostiche contenenti gli stessi

Publications (3)

Publication Number Publication Date
ITMI931479A0 ITMI931479A0 (it) 1993-07-08
ITMI931479A1 ITMI931479A1 (it) 1995-01-08
IT1264690B1 true IT1264690B1 (it) 1996-10-04

Family

ID=11366554

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93MI001479A IT1264690B1 (it) 1993-07-08 1993-07-08 Compositi oligomeri iodurati e composizioni diagnostiche contenenti gli stessi

Country Status (8)

Country Link
EP (1) EP0707572A1 (it)
JP (1) JPH08512297A (it)
AU (1) AU7125194A (it)
IL (1) IL110249A0 (it)
IS (1) IS4189A (it)
IT (1) IT1264690B1 (it)
WO (1) WO1995001966A1 (it)
ZA (1) ZA944923B (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9506372A (pt) * 1994-09-22 1997-09-16 Guerbet Sa Derivados isodados sua preparação e seu uso como agentes de contraste em radiologia de raios x
WO1996009280A1 (fr) * 1994-09-22 1996-03-28 Guerbet S.A. Composes polyiodes, leur preparation et leur application en radiologie x
IT1271134B (it) * 1994-12-01 1997-05-26 Bracco Spa Derivati iodurati del bifenile e loro impiego diagnostico
DE19740403C2 (de) * 1997-09-09 1999-11-11 Schering Ag Neue Kontrastmittel
JP5014573B2 (ja) * 2002-05-09 2012-08-29 オンコサイレオン インコーポレーテッド 脂質ａおよび他の炭水化物リガンド類似体
NO20055702D0 (no) 2005-12-02 2005-12-02 Amersham Health As Contrast agents
EP1986993B1 (en) * 2006-02-14 2012-12-05 Ge Healthcare As Contrast agents
EP1989178B1 (en) * 2006-02-14 2012-10-31 Ge Healthcare As Contrast agents
WO2007094683A1 (en) 2006-02-15 2007-08-23 Ge Healthcare As Contrast agents
EP2021317A1 (en) * 2006-05-11 2009-02-11 GE Healthcare AS Contrast agents
JP5345523B2 (ja) * 2006-05-11 2013-11-20 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
US7662859B2 (en) 2007-02-16 2010-02-16 Ge Healthcare As Contrast agents
WO2008123779A1 (en) * 2007-04-04 2008-10-16 Ge Healthcare As Trisubstituted triazamacrocycli c compounds and their use as contrast agents
NO20073382L (no) * 2007-06-29 2008-12-30 Ge Healthcare As Contrast Agents
CN101820923A (zh) * 2007-10-12 2010-09-01 通用电气医疗集团股份有限公司 对比剂
US8889616B2 (en) 2011-02-24 2014-11-18 Oncothyreon Inc. MUC1 based glycolipopeptide vaccine with adjuvant
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
KR102464647B1 (ko) 2016-11-28 2022-11-08 바이엘 파마 악티엔게젤샤프트 자기 공명 영상화에 사용하기 위한 높은 이완도 가돌리늄 킬레이트 화합물
CN106928087B (zh) * 2017-03-13 2019-01-22 牡丹江医学院 一种ct胃肠道造影剂及其应用
BR112021007707A2 (pt) 2018-11-23 2021-07-27 Bayer Aktiengesellschaft formulação de meios de contraste e processo de preparação da mesma
EP4015509A1 (en) * 2020-12-18 2022-06-22 Justesa Imagen S.A.U Organometallic compounds and their use as multimodal contrasting media for imaging diagnosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065553A (en) * 1974-05-31 1977-12-27 Laboratoires Andre Guerbet X-Ray contrast media
GB1491129A (en) * 1975-06-04 1977-11-09 Guerbet Sa Iodo-benzene derivatives and an x-ray contrast medium containing them
US5162109A (en) * 1990-09-13 1992-11-10 Mallinckrodt Medical, Inc. Magnetic resonance imaging agents
US5019371A (en) * 1990-11-21 1991-05-28 Mallinckrodt Medical, Inc. Novel x-ray contrast agents, compositions and methods

Also Published As

Publication number Publication date
ZA944923B (en) 1995-03-14
JPH08512297A (ja) 1996-12-24
IS4189A (is) 1995-01-09
EP0707572A1 (en) 1996-04-24
WO1995001966A1 (en) 1995-01-19
IL110249A0 (en) 1994-10-21
ITMI931479A1 (it) 1995-01-08
AU7125194A (en) 1995-02-06
ITMI931479A0 (it) 1993-07-08

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Legal Events

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970729