IT1252692B - Composizione farmaceutica per uso oftalmico contenente un antiinfiammatorio non steroideo ed un decongestionante come principi attivi - Google Patents
Composizione farmaceutica per uso oftalmico contenente un antiinfiammatorio non steroideo ed un decongestionante come principi attiviInfo
- Publication number
- IT1252692B IT1252692B ITMI913170A ITMI913170A IT1252692B IT 1252692 B IT1252692 B IT 1252692B IT MI913170 A ITMI913170 A IT MI913170A IT MI913170 A ITMI913170 A IT MI913170A IT 1252692 B IT1252692 B IT 1252692B
- Authority
- IT
- Italy
- Prior art keywords
- pharmaceutical composition
- decongestant
- inflammatory
- use containing
- ophthalmic use
- Prior art date
Links
- 239000000850 decongestant Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 abstract 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 1
- 229960000502 poloxamer Drugs 0.000 abstract 1
- 229920001983 poloxamer Polymers 0.000 abstract 1
- 229950008882 polysorbate Drugs 0.000 abstract 1
- 229920000136 polysorbate Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Abstract
Viene descritta una composizione farmaceutica sotto forma di soluzione acquosa per uso oftalmico contenente un'associazione di un farmaco antiinfiammatorio non steroideo, avente un gruppo carbossilico, e di un farmaco decongestionante e una miscela di polisorbato e poloxamero con solubilizzante.
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI913170A IT1252692B (it) | 1991-11-27 | 1991-11-27 | Composizione farmaceutica per uso oftalmico contenente un antiinfiammatorio non steroideo ed un decongestionante come principi attivi |
EP92203632A EP0550921B1 (en) | 1991-11-27 | 1992-11-25 | Pharmaceutical composition for ophthalmic use comprising a nonsteroidal anti-inflammatory and a decongestant drug |
AT92203632T ATE177633T1 (de) | 1991-11-27 | 1992-11-25 | Nichtsteroide-entzündungshemmende arzneimittel und decongestirum enthaltende augenarzneimittelzusammensetzung |
DE69228674T DE69228674T2 (de) | 1991-11-27 | 1992-11-25 | Nichtsteroide-entzündungshemmende Arzneimittel und Decongestirum enthaltende Augenarzneimittelzusammensetzung |
ES92203632T ES2131517T3 (es) | 1991-11-27 | 1992-11-25 | Composicion farmaceutica de uso oftalmologico que comprende un agente antiinflamatorio no esteroide y un agente anticongestivo. |
US08/210,743 US5459157A (en) | 1991-11-27 | 1994-03-21 | Pharmaceutical composition for ophthalmic use comprising a nonsteroidal anti-inflammatory and a decongestant drug |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI913170A IT1252692B (it) | 1991-11-27 | 1991-11-27 | Composizione farmaceutica per uso oftalmico contenente un antiinfiammatorio non steroideo ed un decongestionante come principi attivi |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI913170A0 ITMI913170A0 (it) | 1991-11-27 |
ITMI913170A1 ITMI913170A1 (it) | 1993-05-28 |
IT1252692B true IT1252692B (it) | 1995-06-23 |
Family
ID=11361205
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI913170A IT1252692B (it) | 1991-11-27 | 1991-11-27 | Composizione farmaceutica per uso oftalmico contenente un antiinfiammatorio non steroideo ed un decongestionante come principi attivi |
Country Status (6)
Country | Link |
---|---|
US (1) | US5459157A (it) |
EP (1) | EP0550921B1 (it) |
AT (1) | ATE177633T1 (it) |
DE (1) | DE69228674T2 (it) |
ES (1) | ES2131517T3 (it) |
IT (1) | IT1252692B (it) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5474985A (en) * | 1993-12-22 | 1995-12-12 | The Regents Of The University Of California | Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors |
US5674888A (en) * | 1995-06-07 | 1997-10-07 | University Of California | Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division |
US5599535A (en) * | 1995-06-07 | 1997-02-04 | Regents Of The University Of California | Methods for the cyto-protection of the trabecular meshwork |
US20060029653A1 (en) | 1997-01-29 | 2006-02-09 | Cronk Peter J | Therapeutic delivery system |
US6550474B1 (en) | 1997-01-29 | 2003-04-22 | Cns, Inc. | Microencapsulated fragrances and methods of coating microcapsules |
US6769428B2 (en) | 1997-01-29 | 2004-08-03 | Peter J. Cronk | Adhesively applied external nasal strips and dilators containing medications and fragrances |
US6090403A (en) * | 1998-08-17 | 2000-07-18 | Lectec Corporation | Inhalation therapy decongestant with foraminous carrier |
WO2002005853A2 (en) * | 2000-07-14 | 2002-01-24 | Allergan, Inc. | Compositions containing alpha-2-adrenergic agonist components |
US8858961B2 (en) | 2000-07-14 | 2014-10-14 | Allergan, Inc. | Compositions containing alpha-2-adrenergic agonist components |
ITRM20010048A1 (it) | 2001-01-30 | 2002-07-30 | Gregorio Mauro De | Metodo per preparare soluzioni acquose fisiologicamente accettabili esoluzioni cosi' ottenute. |
BG65734B1 (bg) * | 2002-02-22 | 2009-09-30 | Био Терапютикс - Еоод | Течен мукоадхезивен фармацевтичен състав |
US20030191187A1 (en) * | 2002-04-01 | 2003-10-09 | Lee Fang Yu | Injectable pharmaceutical composition containing a non-steroidal anti-inflammatory drug and method for preparing the same |
CN103143022A (zh) | 2002-07-30 | 2013-06-12 | 奥默罗斯公司 | 眼科冲洗液及方法 |
DK1761266T3 (da) * | 2004-05-25 | 2013-08-05 | Galderma Pharma Sa | Forbindelser, formuleringer og fremgangsmåder til at behandle eller forebygge inflammatoriske hudsygdomme |
PL1885336T3 (pl) * | 2005-05-10 | 2009-08-31 | Alcon Inc | Kompozycja w postaci zawiesiny zawierająca substancję aktywną, poloksamerowy lub meroksapolowy surfaktant i glikol oraz zastosowanie kompozycji do wytwarzania leku do leczenia chorób oczu |
RU2009111263A (ru) | 2006-08-30 | 2010-10-10 | Дэвид Уилльям СМИТ (US) | Способ придания одноосевой или многоосевой жесткости экструдированным материалам, а также изделия, получаемые из них |
US20120202863A1 (en) * | 2011-02-03 | 2012-08-09 | Gerald Horn | Compositions and methods for treatment of glaucoma |
AU2013201465B2 (en) | 2012-10-24 | 2016-03-03 | Rayner Surgical (Ireland) Limited | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
US20150164882A1 (en) | 2013-07-22 | 2015-06-18 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical compositions for intraocular administration and methods for fabricating thereof |
US20160279055A1 (en) * | 2013-07-22 | 2016-09-29 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof |
TWI705812B (zh) | 2014-12-01 | 2020-10-01 | 奥默羅斯公司 | 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4734222A (en) * | 1986-04-03 | 1988-03-29 | Ciba-Geigy Corporation | Composition and method for cleaning soft and hard contact lenses |
US5110493A (en) * | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
US4996209A (en) * | 1988-06-20 | 1991-02-26 | Alcon Laboratories, Inc. | Ophthalmic antiinflammatory compositions comprising S(+)-flurbiprofen |
US4988728A (en) * | 1989-11-03 | 1991-01-29 | Alcon Laboratories, Inc. | Suprofen esters and amides as ophthalmic anti-inflammatory agents |
US5077033A (en) * | 1990-08-07 | 1991-12-31 | Mediventures Inc. | Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide |
-
1991
- 1991-11-27 IT ITMI913170A patent/IT1252692B/it active IP Right Grant
-
1992
- 1992-11-25 EP EP92203632A patent/EP0550921B1/en not_active Expired - Lifetime
- 1992-11-25 DE DE69228674T patent/DE69228674T2/de not_active Expired - Fee Related
- 1992-11-25 AT AT92203632T patent/ATE177633T1/de not_active IP Right Cessation
- 1992-11-25 ES ES92203632T patent/ES2131517T3/es not_active Expired - Lifetime
-
1994
- 1994-03-21 US US08/210,743 patent/US5459157A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ITMI913170A1 (it) | 1993-05-28 |
US5459157A (en) | 1995-10-17 |
ES2131517T3 (es) | 1999-08-01 |
EP0550921A1 (en) | 1993-07-14 |
EP0550921B1 (en) | 1999-03-17 |
DE69228674D1 (de) | 1999-04-22 |
ITMI913170A0 (it) | 1991-11-27 |
DE69228674T2 (de) | 1999-07-15 |
ATE177633T1 (de) | 1999-04-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IT1252692B (it) | Composizione farmaceutica per uso oftalmico contenente un antiinfiammatorio non steroideo ed un decongestionante come principi attivi | |
IT8619004A0 (it) | Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche. | |
ATE130758T1 (de) | Arzneimittel zur intranasalen verabreichung, die ketorolac r enthalten. | |
DK383987A (da) | Ny galeniske formuleringer med programmeret afgivelse indeholdende antiphlogistika | |
ES2188782T3 (es) | Formulaciones farmaceuticas que contienen darifenacina. | |
ATE211387T1 (de) | Oral 1alpha-hydroxyprevitamin d | |
ES2183841T3 (es) | Formas de dosificacion para administrar un farmasco en una formulacion lquidid. | |
DE69323442D1 (de) | Flüssige pharmazeutische Formulierung mit verlängerter Wirkstoffabgabe | |
CA2301017A1 (en) | Use of propyl gallate to increase bioavailability of orally administered pharmaceutical compounds | |
NO304261B1 (no) | Preparat omfattende en lipofil forbindelse | |
KR910000703A (ko) | 테트라졸 자극성 아미노산 수용체의 길항물질 | |
IT1264857B1 (it) | Composizione farmaceutica liquida per uso orale contenente acido 2-(4-isobutilfenil) propionico | |
FR2674754B1 (fr) | Composition medicamenteuse micronisee. | |
ES2062137T3 (es) | Utilizacion de 5'-deoxi-5'-metil-tioadenosina, s-adenosilmetionina y sus sales para la preparacion de composiciones farmaceuticas reductoras de seborrea. | |
ATE136778T1 (de) | Oral anzuwendende arzneimittel dapiprazol enthaltend | |
ATE59551T1 (de) | Feste orale arzneiformen mit gestaffelter wirkung zur verabreichung von wirkstoffen mit geschwuere erzeugender nebenwirkung. | |
KR910009265A (ko) | 마취제의 제조에 있어서의 이미다조피리딘의 사용 | |
ATE210986T1 (de) | Zubereitungen von 1,5-benzodiazepinderivaten mit cck-antagonistischen oder agonistischer wirkung mit enterischem überzug | |
IT1254707B (it) | Uso topico della calcitonima per la preparazione di medicamenti nella cataratta idiopatica senile e una composizione farmaceutica che la contiene | |
DE69325531D1 (de) | Oral anzuwendendes Arzneimittel bestehend aus Ibuprofen | |
EP0396169A3 (en) | Pharmaceutical composition for topical ophthalmic use having improved local tolerability | |
ES2146683T3 (es) | Uso de bifemelano para la fabricacion de un medicamento para el tratamiento de trastornos hipercineticos. | |
IT1250412B (it) | Pompa adatta all'erogazione di schiuma contenente antiinfiammatori non steroidei | |
KR927003530A (ko) | 이온삼투요법용 제약 제제의 제조에 있어서의 국소 마취제의 용도 | |
KR930004460A (ko) | 에이(a) 87689 화합물 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971020 |