IT1251991B - USE OF GANGLIOSIDES FOR THE PREPARATION OF ACTIVE PHARMACEUTICAL COMPOSITIONS IN THE PREVENTION OF DYSFUNCTIONS ASSOCIATED WITH THE ABUSE OF COCAINE AND PSYCHOSTIMULANTS RELATED TO IT - Google Patents
USE OF GANGLIOSIDES FOR THE PREPARATION OF ACTIVE PHARMACEUTICAL COMPOSITIONS IN THE PREVENTION OF DYSFUNCTIONS ASSOCIATED WITH THE ABUSE OF COCAINE AND PSYCHOSTIMULANTS RELATED TO ITInfo
- Publication number
- IT1251991B IT1251991B ITMI912987A ITMI912987A IT1251991B IT 1251991 B IT1251991 B IT 1251991B IT MI912987 A ITMI912987 A IT MI912987A IT MI912987 A ITMI912987 A IT MI912987A IT 1251991 B IT1251991 B IT 1251991B
- Authority
- IT
- Italy
- Prior art keywords
- psychostimulants
- abuse
- prevention
- preparation
- pharmaceutical compositions
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 239000003368 psychostimulant agent Substances 0.000 title abstract 2
- ZPUCINDJVBIVPJ-LJISPDSOSA-N ***e Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 title 2
- 229960003920 ***e Drugs 0.000 title 1
- 230000004064 dysfunction Effects 0.000 title 1
- 150000002270 gangliosides Chemical class 0.000 title 1
- 101100322805 Arabidopsis thaliana AHL15 gene Proteins 0.000 abstract 1
- 230000003542 behavioural effect Effects 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- QPJBWNIQKHGLAU-IQZHVAEDSA-N ganglioside GM1 Chemical compound O[C@@H]1[C@@H](O)[C@H](OC[C@H](NC(=O)CCCCCCCCCCCCCCCCC)[C@H](O)\C=C\CCCCCCCCCCCCC)O[C@H](CO)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@]2(O[C@H]([C@H](NC(C)=O)[C@@H](O)C2)[C@H](O)[C@H](O)CO)C(O)=O)[C@@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O3)O)[C@@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](CO)O1 QPJBWNIQKHGLAU-IQZHVAEDSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Viene descritto un nuovo impiego del monosialoganglioside GM1 e del suo estere interno AGF2 e dei loro sali farmacologicamente accettabili per la preparazione di composizioni farmaceutiche attive nella prevenzione di disfunzioni comportamentali e cognitive associate all'abuso di coacina e di psicostimolanti ad essa correlati.A new use of the monosialoganglioside GM1 and its internal ester AGF2 and their pharmacologically acceptable salts for the preparation of pharmaceutical compositions active in the prevention of behavioral and cognitive dysfunctions associated with the abuse of coacin and related psychostimulants is described.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI912987A IT1251991B (en) | 1991-11-08 | 1991-11-08 | USE OF GANGLIOSIDES FOR THE PREPARATION OF ACTIVE PHARMACEUTICAL COMPOSITIONS IN THE PREVENTION OF DYSFUNCTIONS ASSOCIATED WITH THE ABUSE OF COCAINE AND PSYCHOSTIMULANTS RELATED TO IT |
| AU29321/92A AU2932192A (en) | 1991-11-08 | 1992-11-06 | Use of gangliosides in the preparation of pharmaceuticals which can improve the progonosis of disorders due to psychotropics and drugs abuse |
| PCT/EP1992/002579 WO1993008808A2 (en) | 1991-11-08 | 1992-11-06 | Use of gangliosides in the preparation of pharmaceuticals which can improve the progonosis of disorders due to psychotropics and drugs abuse |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI912987A IT1251991B (en) | 1991-11-08 | 1991-11-08 | USE OF GANGLIOSIDES FOR THE PREPARATION OF ACTIVE PHARMACEUTICAL COMPOSITIONS IN THE PREVENTION OF DYSFUNCTIONS ASSOCIATED WITH THE ABUSE OF COCAINE AND PSYCHOSTIMULANTS RELATED TO IT |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI912987A0 ITMI912987A0 (en) | 1991-11-08 |
| ITMI912987A1 ITMI912987A1 (en) | 1993-05-08 |
| IT1251991B true IT1251991B (en) | 1995-05-27 |
Family
ID=11361062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI912987A IT1251991B (en) | 1991-11-08 | 1991-11-08 | USE OF GANGLIOSIDES FOR THE PREPARATION OF ACTIVE PHARMACEUTICAL COMPOSITIONS IN THE PREVENTION OF DYSFUNCTIONS ASSOCIATED WITH THE ABUSE OF COCAINE AND PSYCHOSTIMULANTS RELATED TO IT |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU2932192A (en) |
| IT (1) | IT1251991B (en) |
| WO (1) | WO1993008808A2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0812191B1 (en) * | 1995-04-11 | 2005-07-20 | Samuel Dr. Bogoch | Peptides for the treatment of cancer |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4476119A (en) * | 1981-08-04 | 1984-10-09 | Fidia S.P.A. | Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions |
| IT1212041B (en) * | 1987-11-02 | 1989-11-08 | Fidia Farmaceutici | INTERNAL FOREIGN GANGLIOSIDES AS THERAPEUTIC AGENTS CAPABLE OF ELIMINATING PAIN IN PERIPHERAL NEUROPATHIES |
| AR241751A1 (en) * | 1989-07-12 | 1992-12-30 | Beta Lab Sa | Proceeding for obtaining mixtures from gangliosides for treatment of character and psycho-organic disorders. |
| IT1249034B (en) * | 1990-06-29 | 1995-02-11 | Fidia Spa | USE OF MONOSIALOGANGLIOSIDE GM1 AND ITS INTERNAL FOREIGN DERIVATIVE TO PREVENT THE ESTABLISHMENT OF TOLERANCE IN HUMANS FROM THE ANALGESIC EFFECT OF MORFINA AND ANALOGS |
-
1991
- 1991-11-08 IT ITMI912987A patent/IT1251991B/en active IP Right Grant
-
1992
- 1992-11-06 AU AU29321/92A patent/AU2932192A/en not_active Abandoned
- 1992-11-06 WO PCT/EP1992/002579 patent/WO1993008808A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| AU2932192A (en) | 1993-06-07 |
| ITMI912987A0 (en) | 1991-11-08 |
| WO1993008808A3 (en) | 1993-06-10 |
| ITMI912987A1 (en) | 1993-05-08 |
| WO1993008808A2 (en) | 1993-05-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |