IT1251114B - Forme farmaceutiche antivirali per applicazione vaginale - Google Patents
Forme farmaceutiche antivirali per applicazione vaginaleInfo
- Publication number
- IT1251114B IT1251114B ITMI912071A ITMI912071A IT1251114B IT 1251114 B IT1251114 B IT 1251114B IT MI912071 A ITMI912071 A IT MI912071A IT MI912071 A ITMI912071 A IT MI912071A IT 1251114 B IT1251114 B IT 1251114B
- Authority
- IT
- Italy
- Prior art keywords
- tablets
- effervescent
- vaginal
- pharmaceutical forms
- preparation
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title 1
- 239000010410 layer Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 239000003826 tablet Substances 0.000 abstract 2
- 239000000003 vaginal tablet Substances 0.000 abstract 2
- MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 abstract 1
- 229960004150 aciclovir Drugs 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 239000007938 effervescent tablet Substances 0.000 abstract 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 239000002356 single layer Substances 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gynecology & Obstetrics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Sono descritti preparati farmaceutici destinati alla somministrazione vaginale di farmaci antivirali, preferibilmente di acyclovir. Forme farmaceutiche adatte sono:a) compresse vaginali erodibili e compresse vaginali effervescenti b) compresse effervescenti destinate alla preparazione di bagni medicati e/o granulare effervescente o solubile o dispersibile in acqua per la preparazione di bagni medicati c) compresse ad un solo strato (in genere destinate ad un rilascio immediato della sostanza attiva o al rilascio prolungato o sostenuto)d) compresse a due o più strati (essendo ciascuno dei differenti strati progettato per determinare differenti velocità di rilascio).
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI912071A IT1251114B (it) | 1991-07-26 | 1991-07-26 | Forme farmaceutiche antivirali per applicazione vaginale |
AT92915980T ATE129149T1 (de) | 1991-07-26 | 1992-07-20 | Virushemmende pharmazeutische zubereitungen zur vaginalen verabreichung. |
DE69205579T DE69205579T2 (de) | 1991-07-26 | 1992-07-20 | Virushemmende pharmazeutische zubereitungen zur vaginalen verabreichung. |
PCT/EP1992/001655 WO1993002662A1 (en) | 1991-07-26 | 1992-07-20 | Antiviral pharmaceutical compositions for vaginal administration |
JP5503217A JPH06509348A (ja) | 1991-07-26 | 1992-07-20 | 経膣投与用の抗ウイルス性薬剤組成物 |
CA002114216A CA2114216A1 (en) | 1991-07-26 | 1992-07-20 | Antiviral pharmaceutical compositions for vaginal administration |
DK92915980.4T DK0596935T3 (da) | 1991-07-26 | 1992-07-20 | Antivirale farmaceutiske midler til vaginal administration |
EP92915980A EP0596935B1 (en) | 1991-07-26 | 1992-07-20 | Antiviral pharmaceutical compositions for vaginal administration |
AU23454/92A AU2345492A (en) | 1991-07-26 | 1992-07-20 | Antiviral pharmaceutical compositions for vaginal administration |
CN92111077A CN1082894A (zh) | 1991-07-26 | 1992-08-24 | ***给药的抗病毒药物组合物 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI912071A IT1251114B (it) | 1991-07-26 | 1991-07-26 | Forme farmaceutiche antivirali per applicazione vaginale |
CN92111077A CN1082894A (zh) | 1991-07-26 | 1992-08-24 | ***给药的抗病毒药物组合物 |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI912071A0 ITMI912071A0 (it) | 1991-07-26 |
ITMI912071A1 ITMI912071A1 (it) | 1993-01-27 |
IT1251114B true IT1251114B (it) | 1995-05-04 |
Family
ID=36790864
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI912071A IT1251114B (it) | 1991-07-26 | 1991-07-26 | Forme farmaceutiche antivirali per applicazione vaginale |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0596935B1 (it) |
JP (1) | JPH06509348A (it) |
CN (1) | CN1082894A (it) |
AT (1) | ATE129149T1 (it) |
AU (1) | AU2345492A (it) |
CA (1) | CA2114216A1 (it) |
DE (1) | DE69205579T2 (it) |
DK (1) | DK0596935T3 (it) |
IT (1) | IT1251114B (it) |
WO (1) | WO1993002662A1 (it) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4139883A1 (de) * | 1991-11-29 | 1993-06-03 | Michael Prof Dr Dittgen | Verfahren zur herstellung bioadhaesiver arzneimittel |
FR2710265B1 (fr) * | 1993-09-22 | 1995-10-20 | Adir | Composition pharmaceutique bioadhésive pour la libération contrôlée de principes actifs. |
DE4404011A1 (de) * | 1994-02-09 | 1995-08-10 | Jenapharm Gmbh | Neue, adhäsiv wirkende Zubereitungen für mit Flüssigkeit benetzte Oberflächen, Verfahren und Vorrichtung zur Erfassung der Adhäsionszeit diesbezüglicher Zubereitungen |
UA74168C2 (uk) * | 1999-10-05 | 2005-11-15 | Коламбіа Леборетеріс (Бермуда) Лімітед | Лікування ендометріозу або безпліддя, або покращення плідності та застосування бета-адренергічного агоніста для виробництва лікарського засобу |
RU2310474C2 (ru) | 1999-10-05 | 2007-11-20 | Колумбия Лабораториз (Бермуда) Лимитед | Способ лечения эндометриоза или бесплодия или улучшение способности к воспроизведению потомства и фармацевтическая композиция для его осуществления |
BR0007360A (pt) * | 1999-12-23 | 2001-08-14 | Johnson & Johnson | Composição de liberação controlada |
JP2001240558A (ja) * | 2000-02-29 | 2001-09-04 | Nippon Suisan Kaisha Ltd | 多価不飽和脂肪酸を経粘膜吸収促進剤として含有する固形製剤。 |
CA2422424C (en) * | 2000-09-19 | 2009-12-01 | Cima Labs, Inc. | Pharmaceutical compositions for rectal and vaginal administration |
EP1667619A4 (en) * | 2003-09-19 | 2007-10-10 | Drugtech Corp | PHARMACEUTICAL FEEDING SYSTEM |
NZ548216A (en) | 2003-12-31 | 2010-02-26 | Cima Labs Inc | Generally linear effervescent oral fentanyl dosage form and methods of administering |
CA2549642C (en) | 2003-12-31 | 2012-10-30 | Cima Labs Inc. | Effervescent oral opiate dosage forms and methods of administering opiates |
EP2662086A1 (en) * | 2012-05-08 | 2013-11-13 | Progressare Medinvest B.V. | Composition for the treatment or prevention of urinary tract infections and dosage form |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3388041A (en) * | 1964-01-27 | 1968-06-11 | Richardson Merrell Inc | High dosage sustained release tablet |
JPS52156913A (en) * | 1976-06-21 | 1977-12-27 | Toko Yakuhin Kogyo Kk | Production of injectionable medicine |
JPS5562012A (en) * | 1978-11-06 | 1980-05-10 | Teijin Ltd | Slow-releasing preparation |
JPS58152809A (ja) * | 1982-03-05 | 1983-09-10 | Eisai Co Ltd | 安定な発泡性「膣」坐剤 |
US4389393A (en) * | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
IT1187750B (it) * | 1985-10-15 | 1987-12-23 | Eurand Spa | Procedimento per la preparazione di compresse,anche a rilascio prolungato,di iscsorbide-5-mononitrato stabilizzato e formulazioni cosi' ottenute |
IT1213323B (it) * | 1986-08-07 | 1989-12-20 | Crinos Industria Farmaco | Composizione per uso locale ad atti vita' spermicida virulicida ,disinfettante e/o battericida |
NZ222698A (en) * | 1987-01-08 | 1990-02-26 | Squibb & Sons Inc | Bioadhesive suppository formulations comprising a medicament, water, a hydrocolloid and low melting point base |
US4983393A (en) * | 1987-07-21 | 1991-01-08 | Maximed Corporation | Intra-vaginal device and method for sustained drug release |
-
1991
- 1991-07-26 IT ITMI912071A patent/IT1251114B/it active IP Right Grant
-
1992
- 1992-07-20 DE DE69205579T patent/DE69205579T2/de not_active Expired - Fee Related
- 1992-07-20 DK DK92915980.4T patent/DK0596935T3/da active
- 1992-07-20 WO PCT/EP1992/001655 patent/WO1993002662A1/en active IP Right Grant
- 1992-07-20 AU AU23454/92A patent/AU2345492A/en not_active Abandoned
- 1992-07-20 EP EP92915980A patent/EP0596935B1/en not_active Expired - Lifetime
- 1992-07-20 CA CA002114216A patent/CA2114216A1/en not_active Abandoned
- 1992-07-20 JP JP5503217A patent/JPH06509348A/ja active Pending
- 1992-07-20 AT AT92915980T patent/ATE129149T1/de not_active IP Right Cessation
- 1992-08-24 CN CN92111077A patent/CN1082894A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2114216A1 (en) | 1993-02-18 |
EP0596935A1 (en) | 1994-05-18 |
ATE129149T1 (de) | 1995-11-15 |
AU2345492A (en) | 1993-03-02 |
EP0596935B1 (en) | 1995-10-18 |
ITMI912071A0 (it) | 1991-07-26 |
DK0596935T3 (da) | 1996-01-22 |
CN1082894A (zh) | 1994-03-02 |
WO1993002662A1 (en) | 1993-02-18 |
DE69205579T2 (de) | 1996-04-04 |
ITMI912071A1 (it) | 1993-01-27 |
DE69205579D1 (de) | 1995-11-23 |
JPH06509348A (ja) | 1994-10-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960725 |