IT1235336B - Sale di trometammina di i-metil-beta-osso-alfa-(fenilcarbammoil)-2- pirrolpropionitrile, composizione che lo contiene e procedimento di preparazione ed applicazione - Google Patents

Sale di trometammina di i-metil-beta-osso-alfa-(fenilcarbammoil)-2- pirrolpropionitrile, composizione che lo contiene e procedimento di preparazione ed applicazione

Info

Publication number
IT1235336B
IT1235336B IT8848657A IT4865788A IT1235336B IT 1235336 B IT1235336 B IT 1235336B IT 8848657 A IT8848657 A IT 8848657A IT 4865788 A IT4865788 A IT 4865788A IT 1235336 B IT1235336 B IT 1235336B
Authority
IT
Italy
Prior art keywords
thometamine
pyrolpropionitrile
fenylcarbammoil
bone
beta
Prior art date
Application number
IT8848657A
Other languages
English (en)
Other versions
IT8848657A0 (it
Inventor
Gordon N Walker
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IT8848657A0 publication Critical patent/IT8848657A0/it
Application granted granted Critical
Publication of IT1235336B publication Critical patent/IT1235336B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
IT8848657A 1987-12-18 1988-12-15 Sale di trometammina di i-metil-beta-osso-alfa-(fenilcarbammoil)-2- pirrolpropionitrile, composizione che lo contiene e procedimento di preparazione ed applicazione IT1235336B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/003413 WO1989005798A1 (en) 1987-12-18 1987-12-18 TROMETHAMINE SALT OF 1-METHYL-beta-OXO-alpha-(PHENYLCARBAMOYL)-2-PYRROLEPROPIONITRILE

Publications (2)

Publication Number Publication Date
IT8848657A0 IT8848657A0 (it) 1988-12-15
IT1235336B true IT1235336B (it) 1992-06-30

Family

ID=22202723

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8848657A IT1235336B (it) 1987-12-18 1988-12-15 Sale di trometammina di i-metil-beta-osso-alfa-(fenilcarbammoil)-2- pirrolpropionitrile, composizione che lo contiene e procedimento di preparazione ed applicazione

Country Status (22)

Country Link
US (1) US4977181A (it)
JP (1) JPH02502534A (it)
KR (1) KR890009868A (it)
AT (1) AT390437B (it)
AU (1) AU3596889A (it)
DD (1) DD283375A5 (it)
DE (1) DE3842250A1 (it)
DK (1) DK704188A (it)
ES (1) ES2012578A6 (it)
FI (1) FI885828A (it)
FR (1) FR2624856A1 (it)
GB (1) GB2211187A (it)
HU (1) HU199788B (it)
IL (1) IL88654A0 (it)
IT (1) IT1235336B (it)
LU (1) LU87406A1 (it)
NL (1) NL8803092A (it)
NO (1) NO885576L (it)
PT (1) PT88104A (it)
WO (1) WO1989005798A1 (it)
YU (1) YU227788A (it)
ZA (1) ZA889355B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989005798A1 (en) * 1987-12-18 1989-06-29 Ciba-Geigy Ag TROMETHAMINE SALT OF 1-METHYL-beta-OXO-alpha-(PHENYLCARBAMOYL)-2-PYRROLEPROPIONITRILE
ES2058024B1 (es) * 1992-11-10 1995-05-01 Menarini Lab Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico.
US5431717A (en) * 1993-12-03 1995-07-11 Geobiotics, Inc. Method for rendering refractory sulfide ores more susceptible to biooxidation
US7008979B2 (en) 2002-04-30 2006-03-07 Hydromer, Inc. Coating composition for multiple hydrophilic applications
KR100576332B1 (ko) 2004-07-16 2006-05-03 강승우 신규한 글라이세리드 유도체 및 이를 포함하는 통증완화용조성물
EP3210629A1 (en) 2012-05-30 2017-08-30 Fresenius Kabi Oncology Ltd Pharmaceutical composition of pemetrexed

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4028772A (en) * 1971-04-02 1973-09-27 Merck & Co., Inc Chemical processes
GB1398072A (en) * 1971-06-14 1975-06-18 May & Baker Ltd Cyclopentane derivatives
US4089969A (en) * 1976-07-14 1978-05-16 Syntex (U.S.A.) Inc. 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
US4256759A (en) * 1979-06-11 1981-03-17 Ciba-Geigy Corporation Alphacarbamoyl-pyrrolpropionitriles
DD151307A5 (de) * 1979-06-11 1981-10-14 Ciba Geigy Ag Verfahren zur herstellung von alphacarbamoyl-pyrrol-propionitrilen
HU185926B (en) * 1979-09-27 1985-04-28 Agostne Kahan Process for preparing water soluble derivatives of non-steroid antiinflammatory compositions and pharmaceutical compositins containing such derivatives
US4644010A (en) * 1982-09-28 1987-02-17 Ciba-Geigy Corporation Certain β-oxo-α-carbamoylpyrrolepropionitriles
WO1989005798A1 (en) * 1987-12-18 1989-06-29 Ciba-Geigy Ag TROMETHAMINE SALT OF 1-METHYL-beta-OXO-alpha-(PHENYLCARBAMOYL)-2-PYRROLEPROPIONITRILE

Also Published As

Publication number Publication date
NO885576L (no) 1989-06-19
AU3596889A (en) 1990-01-11
NO885576D0 (no) 1988-12-15
ES2012578A6 (es) 1990-04-01
LU87406A1 (de) 1990-02-28
GB8829136D0 (en) 1989-01-25
GB2211187A (en) 1989-06-28
ATA307488A (de) 1989-10-15
NL8803092A (nl) 1989-07-17
JPH02502534A (ja) 1990-08-16
FI885828A (fi) 1989-06-19
YU227788A (en) 1990-08-31
FI885828A0 (fi) 1988-12-16
FR2624856A1 (en) 1989-06-23
WO1989005798A1 (en) 1989-06-29
AT390437B (de) 1990-05-10
IL88654A0 (en) 1989-07-31
DK704188D0 (da) 1988-12-16
DE3842250A1 (de) 1989-06-29
ZA889355B (en) 1989-10-25
DD283375A5 (de) 1990-10-10
DK704188A (da) 1989-06-19
PT88104A (pt) 1989-09-14
US4977181A (en) 1990-12-11
HU199788B (en) 1990-03-28
KR890009868A (ko) 1989-08-04
IT8848657A0 (it) 1988-12-15
HUT48582A (en) 1989-06-28

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