IT1228462B - Derivati del 1 arilsolfonil pirrolidin 2 tione oppure del 1 arilsolfonil piperidin 2 tione, loro procedimento di preparazione e loro impiego come medicinali. - Google Patents

Derivati del 1 arilsolfonil pirrolidin 2 tione oppure del 1 arilsolfonil piperidin 2 tione, loro procedimento di preparazione e loro impiego come medicinali.

Info

Publication number
IT1228462B
IT1228462B IT8919543A IT1954389A IT1228462B IT 1228462 B IT1228462 B IT 1228462B IT 8919543 A IT8919543 A IT 8919543A IT 1954389 A IT1954389 A IT 1954389A IT 1228462 B IT1228462 B IT 1228462B
Authority
IT
Italy
Prior art keywords
arilsolfonil
tione
pirrolidin
piperidin
derivatives
Prior art date
Application number
IT8919543A
Other languages
English (en)
Other versions
IT8919543A0 (it
Inventor
Emilio Toja
Fernando Barzaghi
Giulio Galliani
Original Assignee
Roussel Maestretti S P A Milan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Maestretti S P A Milan filed Critical Roussel Maestretti S P A Milan
Publication of IT8919543A0 publication Critical patent/IT8919543A0/it
Priority to IT8919543A priority Critical patent/IT1228462B/it
Priority to MX1956690A priority patent/MX19566A/es
Priority to EG9990A priority patent/EG18746A/xx
Priority to MA22013A priority patent/MA21751A1/fr
Priority to US07/482,500 priority patent/US5037822A/en
Priority to ZA901312A priority patent/ZA901312B/xx
Priority to HU90888A priority patent/HU208815B/hu
Priority to AU50017/90A priority patent/AU625783B2/en
Priority to KR1019900002251A priority patent/KR910015534A/ko
Priority to PT93229A priority patent/PT93229A/pt
Priority to JP2039911A priority patent/JPH02300163A/ja
Priority to TNTNSN90019A priority patent/TNSN90019A1/fr
Priority to EP19900400495 priority patent/EP0384844A3/fr
Priority to SU904743130A priority patent/RU1836347C/ru
Priority to CA002010713A priority patent/CA2010713A1/fr
Application granted granted Critical
Publication of IT1228462B publication Critical patent/IT1228462B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96—Sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT8919543A 1989-02-23 1989-02-23 Derivati del 1 arilsolfonil pirrolidin 2 tione oppure del 1 arilsolfonil piperidin 2 tione, loro procedimento di preparazione e loro impiego come medicinali. IT1228462B (it)

Priority Applications (15)

Application Number Priority Date Filing Date Title
IT8919543A IT1228462B (it) 1989-02-23 1989-02-23 Derivati del 1 arilsolfonil pirrolidin 2 tione oppure del 1 arilsolfonil piperidin 2 tione, loro procedimento di preparazione e loro impiego come medicinali.
MX1956690A MX19566A (es) 1989-02-23 1990-02-19 Nuevos derivados de 1-arilsulfonil-pirrolidin-2-tiona o de 1-arilsulfonil-piperidin-2-tiona y procedimiento para su preparacion
EG9990A EG18746A (en) 1989-02-23 1990-02-20 Process for preparing of new 1 - arylsulsulphony 1 - r - pyrrolid - inethion of 1 - arylsulphonyl - 2 - piperidinethione derivatives
MA22013A MA21751A1 (fr) 1989-02-23 1990-02-20 Procede de preparation de nouveaux derives de la i - arylsulfonyl pyrrolydin- 2 -thione ou de la i - arylsulfonyl piperidine -2-thione .
HU90888A HU208815B (en) 1989-02-23 1990-02-21 Process for producing 1-aryl-sulfonyl-pirrolidine-2-thion- and 1-arylsulfonyl-piperidine-2-thion derivatives
ZA901312A ZA901312B (en) 1989-02-23 1990-02-21 1-arylsulphonyl-2-pyrrolidinethione or 1-arylsulphonyl-2-piperidinethione derivatives,process for their preparation and compositions containing them
US07/482,500 US5037822A (en) 1989-02-23 1990-02-21 1-arylsulphonyl-2-pyrrolidinethione or 1-arylsulphonyl-2-piperidinethione derivatives, process for the preparation thereof their application as medicinal products and compositions containing them
AU50017/90A AU625783B2 (en) 1989-02-23 1990-02-22 New 1-arylsulphonyl-2-pyrrolidinethione or 1-arylsulphonyl-2 -piperidinethione derivatives, process for the preparation thereof, their application as medicinal products and compositions containing them
KR1019900002251A KR910015534A (ko) 1989-02-23 1990-02-22 신규 1-아릴술포닐-2-피롤리딘티온 또는 1-아릴술포닐-2- 피페리딘티온 유도체, 이의 제조방법, 의약품으로서의 용도 및 이 화합물을 함유하는 조성물
PT93229A PT93229A (pt) 1989-02-23 1990-02-22 Processo para a preparacao de novos derivados da 1-arilsulfonil firrolidin-2- tiona ou da 1-arilsulfonil piperidin-2-tiona e de composicoes farmaceuticas que os contem
JP2039911A JPH02300163A (ja) 1989-02-23 1990-02-22 新規な１―アリールスルホニル―２―ピロリジンチオン又は１―アリールスルホニル―２―ピペリジンチオン誘導体、それらの製造方法、薬剤としての使用及びそれらを含有する組成物
TNTNSN90019A TNSN90019A1 (fr) 1989-02-23 1990-02-22 Procede de preparation de nouveaux derives de la 1-arylsulfonyl pyrrolidin-2-thione ou de la 1-arylsulfonyl piperidin-2-thione
EP19900400495 EP0384844A3 (fr) 1989-02-23 1990-02-22 Nouveaux dérivés de la 1-arylsulfonyl pyrrollidin-2-thione ou de la 1-aryl-sulfonyl pipéridin-2-thione, leur procédé de préparation, leur application comme médicaments et les compositions les renfermant
SU904743130A RU1836347C (ru) 1989-02-23 1990-02-22 Способ получени производных 1-арилсульфонилпирролидин-2-тиона или 1-арилсульфонилпиперидин-2-тиона
CA002010713A CA2010713A1 (fr) 1989-02-23 1990-02-22 Derives de la 1-arylsulfonyl pyrrolidin-2-thione ou de la 1-arylsulfonyl piperidin-2-thione, leur procede de preparation, leur application comme medicaments et les compositions les renfermant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8919543A IT1228462B (it) 1989-02-23 1989-02-23 Derivati del 1 arilsolfonil pirrolidin 2 tione oppure del 1 arilsolfonil piperidin 2 tione, loro procedimento di preparazione e loro impiego come medicinali.

Publications (2)

Publication Number Publication Date
IT8919543A0 IT8919543A0 (it) 1989-02-23
IT1228462B true IT1228462B (it) 1991-06-19

Family

ID=11158915

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8919543A IT1228462B (it) 1989-02-23 1989-02-23 Derivati del 1 arilsolfonil pirrolidin 2 tione oppure del 1 arilsolfonil piperidin 2 tione, loro procedimento di preparazione e loro impiego come medicinali.

Country Status (15)

Country Link
US (1) US5037822A (it)
EP (1) EP0384844A3 (it)
JP (1) JPH02300163A (it)
KR (1) KR910015534A (it)
AU (1) AU625783B2 (it)
CA (1) CA2010713A1 (it)
EG (1) EG18746A (it)
HU (1) HU208815B (it)
IT (1) IT1228462B (it)
MA (1) MA21751A1 (it)
MX (1) MX19566A (it)
PT (1) PT93229A (it)
RU (1) RU1836347C (it)
TN (1) TNSN90019A1 (it)
ZA (1) ZA901312B (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1244881B (it) * 1990-12-13 1994-09-12 Roussel Pharma Spa Derivati dell'1-arilsolfonil 2-pirrolidone, loro procedimento di preparazione e i nuovi intermedi cosi' ottenuti ,il loro impiego come farmaci e le composizioni farmaceutiche che li contengono
US5707985A (en) * 1995-06-07 1998-01-13 Tanabe Seiyaku Co. Ltd. Naphthyl-, quinolyl- and isoquinolyl- sulfonamide derivatives as cell adhesion modulators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3117975A (en) * 1960-04-22 1964-01-14 Rohm & Haas Substituted pyrrolidinones and piperidinones
FR2553409B1 (fr) * 1983-10-18 1986-04-18 Choay Sa Nouveaux benzenesulfonyl-lactames, leur procede de preparation et leur application comme substance active de compositions pharmaceutiques
DK167393B1 (da) * 1985-12-30 1993-10-25 Roussel Uclaf 1-sulfonyl-2-oxo-pyrrolidinderivater, deres fremstilling og farmaceutiske praeparater med indhold deraf
IT1215590B (it) * 1987-06-29 1990-02-14 Roussel Maestretti Spa Derivati della 1-benzene solfonil 2-oco 5-alchiltio pirrolidina, un loro procedimentodi preparazione e il loro impiegocome stostanze medicinali.
IT1216461B (it) * 1988-02-26 1990-03-08 Milano Derivati del 1_aril solfonil2_pirrolidinone loro procedimentodi preparazione e loro impieto come medicinali.

Also Published As

Publication number Publication date
PT93229A (pt) 1990-08-31
MA21751A1 (fr) 1990-10-01
EP0384844A3 (fr) 1991-11-21
MX19566A (es) 1993-11-01
RU1836347C (ru) 1993-08-23
KR910015534A (ko) 1991-09-30
EP0384844A2 (fr) 1990-08-29
IT8919543A0 (it) 1989-02-23
AU625783B2 (en) 1992-07-16
ZA901312B (en) 1991-04-24
HU900888D0 (en) 1990-05-28
JPH02300163A (ja) 1990-12-12
EG18746A (en) 1994-02-28
US5037822A (en) 1991-08-06
CA2010713A1 (fr) 1990-08-23
TNSN90019A1 (fr) 1991-03-05
AU5001790A (en) 1990-10-25
HUT53884A (en) 1990-12-28
HU208815B (en) 1995-07-28

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960206