IT1224225B - New 4-oxo:quinoline-3-carboxylic acid cpds. - Google Patents
New 4-oxo:quinoline-3-carboxylic acid cpds.Info
- Publication number
- IT1224225B IT1224225B IT8767130A IT6713087A IT1224225B IT 1224225 B IT1224225 B IT 1224225B IT 8767130 A IT8767130 A IT 8767130A IT 6713087 A IT6713087 A IT 6713087A IT 1224225 B IT1224225 B IT 1224225B
- Authority
- IT
- Italy
- Prior art keywords
- carboxylic acid
- substd
- oxo
- new
- thiomorpholino
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
(+8.5.86, 22.5.86, 23.7.86, 19.8.86, 30.9.86, 15.10.86, 18.12.86-JP-105655, 118568, 173370, 193838, 233837, 246050, 303515) (1703KM) 4-Oxoquinoline-3-carboxylic acid cpds. of formula (I) and their salts are new. R1 is cyclopropyl opt. substd. by 1-3 substits. selected from lower alkyl and halogen; R2 is 5-9 membered opt. unsatd. heterocyclic ring which may be substd. R3 is lower alkyl which may be substd. by 1-3 substits. selected from a 5- or 6-membered satd. heterocyclic ring, lower alkylthio, amino, lower-alkylamino, lower alkanoyloxy, OH, lower alkoxy and halogen; and X is halogen. Pref. R2 is opt. substd. 1-piperidinyl, 1-pyrrolidinyl, 1-homopiperazinyl, thiomorpholino, 1,4-diazabicyclo (4.3.0) nona-4-yl, thiomorpholino-4-oxide, thiomorpholino-4,4-dioxide, 1-hexahydropyridazinyl, 2-thiazolidinyl, 1-imidazolidinyl or 3,7-diazabicyclo (4.3.0) nona-3-yl. 10 Cpds. of (I) including 7-(4-(5-methyl) 2-oxo-1,3-dioxolen -4-yl) methyl-1-piperazinyl) -1-cyclopropyl-6-fluoro- 8-methyl-1,4-dihydro-4-oxoquinoline -3-carboxylic acid are described.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4092186 | 1986-02-25 | ||
JP10565586 | 1986-05-08 | ||
JP11856886 | 1986-05-22 | ||
JP17337086 | 1986-07-23 | ||
JP19383886 | 1986-08-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8767130A0 IT8767130A0 (en) | 1987-02-24 |
IT1224225B true IT1224225B (en) | 1990-09-26 |
Family
ID=27522123
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT8767130A IT1224225B (en) | 1986-02-25 | 1987-02-24 | New 4-oxo:quinoline-3-carboxylic acid cpds. |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1224225B (en) |
-
1987
- 1987-02-24 IT IT8767130A patent/IT1224225B/en active
Also Published As
Publication number | Publication date |
---|---|
IT8767130A0 (en) | 1987-02-24 |
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