IT1217837B - Procedimento per la preparazione del "alfa /4(1,1 dimetiletil)fenil/piperidinbutanolo" - Google Patents

Procedimento per la preparazione del "alfa /4(1,1 dimetiletil)fenil/piperidinbutanolo"

Info

Publication number
IT1217837B
IT1217837B IT21003/88A IT2100388A IT1217837B IT 1217837 B IT1217837 B IT 1217837B IT 21003/88 A IT21003/88 A IT 21003/88A IT 2100388 A IT2100388 A IT 2100388A IT 1217837 B IT1217837 B IT 1217837B
Authority
IT
Italy
Prior art keywords
piperidinbutanol
fenyl
dimethylethyl
alpha
procedure
Prior art date
Application number
IT21003/88A
Other languages
English (en)
Other versions
IT8821003A0 (it
Inventor
Ambrogio Magni
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of IT8821003A0 publication Critical patent/IT8821003A0/it
Priority to IT21003/88A priority Critical patent/IT1217837B/it
Priority to EP19890110377 priority patent/EP0346765A3/en
Priority to DK287289A priority patent/DK287289A/da
Priority to IL90616A priority patent/IL90616A0/xx
Priority to JP1150665A priority patent/JPH0245467A/ja
Priority to ZA894560A priority patent/ZA894560B/xx
Priority to CA000602993A priority patent/CA1309101C/en
Priority to HU893123A priority patent/HU205072B/hu
Priority to KR1019890008317A priority patent/KR900000350A/ko
Application granted granted Critical
Publication of IT1217837B publication Critical patent/IT1217837B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
IT21003/88A 1988-06-17 1988-06-17 Procedimento per la preparazione del "alfa /4(1,1 dimetiletil)fenil/piperidinbutanolo" IT1217837B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT21003/88A IT1217837B (it) 1988-06-17 1988-06-17 Procedimento per la preparazione del "alfa /4(1,1 dimetiletil)fenil/piperidinbutanolo"
EP19890110377 EP0346765A3 (en) 1988-06-17 1989-06-08 Process for preparing 1-(p-tert-butylphenyl)-4-[4'-(alpha-hydroxy-diphenylmethyl)-1'-piperidinyl]butanol
DK287289A DK287289A (da) 1988-06-17 1989-06-13 Fremgangsmaade til fremstilling af 1-(p-tert-butylfenyl)-4-oe4'-(alfa-hydroxydifenylmetyl)-1'-piperidinylaa-butanol
IL90616A IL90616A0 (en) 1988-06-17 1989-06-14 Process for preparing 1-(p-tert-butylphenyl)-4-(4'-(alpha-hydroxy-diphenylmethyl)-1'-piperidinyl)butanol
JP1150665A JPH0245467A (ja) 1988-06-17 1989-06-15 １‐（ｐ‐ターシヤリー‐ブチルフエニル）‐４‐［４’‐（アルフア‐ヒドロキシ‐ジフエニルメチル）‐１’‐ピペリジニル］ブタノールの製造方法
ZA894560A ZA894560B (en) 1988-06-17 1989-06-15 Process for preparing 1-(p-tert-butylphenyl)-4(4'-(alpha hydroxy-diphenylmethyl)-1'-pyperidinyl)butanol
CA000602993A CA1309101C (en) 1988-06-17 1989-06-16 Process for preparing 1-(p-tert-butylphenyl)-4- [4'-(alpha-hydroxy-diphenylmethyl)-1'-piperidinyl] butanol
HU893123A HU205072B (en) 1988-06-17 1989-06-16 Process for producing polymorphous 1-(p-tert.butylphenyl)-4-/4'(alpha-hydroxydiphenyl methyl)-1'-piperidinyl/-butanol having high melting point
KR1019890008317A KR900000350A (ko) 1988-06-17 1989-06-16 1-(p-tert-부틸페닐)-4[4'-(알파-히드록시-디페닐메틸)-1´-피페리디닐]부탄올의 제조 방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21003/88A IT1217837B (it) 1988-06-17 1988-06-17 Procedimento per la preparazione del "alfa /4(1,1 dimetiletil)fenil/piperidinbutanolo"

Publications (2)

Publication Number Publication Date
IT8821003A0 IT8821003A0 (it) 1988-06-17
IT1217837B true IT1217837B (it) 1990-03-30

Family

ID=11175262

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21003/88A IT1217837B (it) 1988-06-17 1988-06-17 Procedimento per la preparazione del "alfa /4(1,1 dimetiletil)fenil/piperidinbutanolo"

Country Status (9)

Country Link
EP (1) EP0346765A3 (it)
JP (1) JPH0245467A (it)
KR (1) KR900000350A (it)
CA (1) CA1309101C (it)
DK (1) DK287289A (it)
HU (1) HU205072B (it)
IL (1) IL90616A0 (it)
IT (1) IT1217837B (it)
ZA (1) ZA894560B (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2015390A1 (en) * 1989-05-01 1990-11-01 Frederick J. Mccarty Process for the preparation of the high melting polymorphic of terfenadine
FR2681861B1 (fr) * 1991-10-01 1995-06-09 Isochem Sa Procede de preparation d'une forme polymorphique de la terfenadine, a point de fusion eleve, d'une plus grande purete et produit obtenu.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742175A (en) * 1986-05-07 1988-05-03 Merrell Dow Pharmaceuticals Inc. Preparation of polymorphically pure terfenadine

Also Published As

Publication number Publication date
HU205072B (en) 1992-03-30
ZA894560B (en) 1990-05-30
DK287289D0 (da) 1989-06-13
IT8821003A0 (it) 1988-06-17
IL90616A0 (en) 1990-01-18
CA1309101C (en) 1992-10-20
EP0346765A2 (en) 1989-12-20
KR900000350A (ko) 1990-01-30
HUT50770A (en) 1990-03-28
DK287289A (da) 1989-12-18
JPH0245467A (ja) 1990-02-15
EP0346765A3 (en) 1990-10-17

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