IT1212984B - MANUFACTURE AND EXPRESSION OF GENES FOR UROGASTRONE AND ITS POLYPEPTIDAL ANALOGUES - Google Patents

MANUFACTURE AND EXPRESSION OF GENES FOR UROGASTRONE AND ITS POLYPEPTIDAL ANALOGUES

Info

Publication number: IT1212984B
Authority: IT; Italy
Prior art keywords: polypeptidal; urogastrone; analogues; genes; expression
Prior art date: 1982-05-06

Application number

IT8367501A

Other languages

Italian (it)

Other versions

IT8367501A0 (en

Inventor

Allen R Banks

David L Hare

Original Assignee

Applied Molecular Genetics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-06

Filing date

1983-05-06

Publication date

1989-12-07

1983-05-06 Application filed by Applied Molecular Genetics Inc filed Critical Applied Molecular Genetics Inc

1983-05-06 Publication of IT8367501A0 publication Critical patent/IT8367501A0/en

1989-12-07 Application granted granted Critical

1989-12-07 Publication of IT1212984B publication Critical patent/IT1212984B/en

Links

102000009024 Epidermal Growth Factor Human genes 0.000 title 1
101800003838 Epidermal growth factor Proteins 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
108090000623 proteins and genes Proteins 0.000 title 1
VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Toxicology (AREA)
Microbiology (AREA)
Medicinal Chemistry (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

IT8367501A 1982-05-06 1983-05-06 MANUFACTURE AND EXPRESSION OF GENES FOR UROGASTRONE AND ITS POLYPEPTIDAL ANALOGUES IT1212984B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US37550082A	1982-05-06	1982-05-06
US48609183A	1983-04-25	1983-04-25

Publications (2)

Publication Number	Publication Date
IT8367501A0 IT8367501A0 (en)	1983-05-06
IT1212984B true IT1212984B (en)	1989-12-07

Family

ID=27007082

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT8367501A IT1212984B (en)	1982-05-06	1983-05-06	MANUFACTURE AND EXPRESSION OF GENES FOR UROGASTRONE AND ITS POLYPEPTIDAL ANALOGUES

Country Status (4)

Country	Link
EP (1)	EP0108132A1 (en)
CA (1)	CA1214739A (en)
IT (1)	IT1212984B (en)
WO (1)	WO1983004030A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4652639A (en) *	1982-05-06	1987-03-24	Amgen	Manufacture and expression of structural genes
IL71991A (en)	1983-06-06	1994-05-30	Genentech Inc	Preparation of mature human IGF and EGF via prokaryotic recombinant DNA technology
US4710473A (en) *	1983-08-10	1987-12-01	Amgen, Inc.	DNA plasmids
US4870008A (en) *	1983-08-12	1989-09-26	Chiron Corporation	Secretory expression in eukaryotes
US4935370A (en) *	1983-12-23	1990-06-19	Pfizer Inc.	Expression plasmids for improved production of heterologous protein in bacteria
ATE66251T1 (en) *	1983-12-23	1991-08-15	Pfizer	EXPRESSION PLASMIDS FOR THE PRODUCTION OF A HETEROLOGOUS PROTEIN IN BACTERIA.
US4745179A (en) *	1984-04-02	1988-05-17	Fujisawa Pharmaceutical Co., Ltd.	59 Valine insulin-like growth factor I and process for production thereof
JP2554459B2 (en) *	1984-07-02	1996-11-13	アース製薬株式会社	β-urogastron gene, corresponding plasmid recombinant and corresponding transformant
CA1263619A (en) *	1984-10-09	1989-12-05	Ryuji Marumoto	Dna, production and use thereof
JP2549504B2 (en) *	1984-12-21	1996-10-30	ア−ス製薬株式会社	DNA base sequence, polypeptide secretory expression vector and transformed microorganism
US4743679A (en) *	1986-02-24	1988-05-10	Creative Biomolecules, Inc.	Process for producing human epidermal growth factor and analogs thereof
GB2188933A (en) *	1986-04-10	1987-10-14	Bayer Ag	Expression vectors for production of polypeptides, method for enhanced expression of polypeptides, hosts containing the expression vectors, products manufactured thereby
IN165717B (en) *	1986-08-07	1989-12-23	Battelle Memorial Institute
US5013653A (en) *	1987-03-20	1991-05-07	Creative Biomolecules, Inc.	Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage
AU605291B2 (en) *	1987-03-20	1991-01-10	Micromet Ag	Process for the purification of recombinant polypeptides
US5472702A (en) *	1987-08-26	1995-12-05	United States Surgical Corporation	Sterilization of growth factors
US5366081A (en) *	1987-08-26	1994-11-22	United States Surgical Corporation	Packaged synthetic absorbable surgical elements
FI891308A (en) *	1988-03-24	1989-09-25	Oncogen	NYA POLYPEPTIDER MED TILLVAEXTFAKTORAKTIVITET OCH DESSA KODANDE NUCLEIN SYRASE SEQUENTOR.
US5102789A (en) *	1989-03-15	1992-04-07	The Salk Institute Biotechnology/Industrial Associates, Inc.	Production of epideramal growth factor in pichia pastoris yeast cells
CA2059245C (en) *	1991-02-08	2004-07-06	Michael P. Chesterfield	Method and apparatus for calendering and coating/filling sutures
US5904716A (en) *	1995-04-26	1999-05-18	Gendler; El	Method for reconstituting cartilage tissue using demineralized bone and product thereof
US20090192554A1 (en)	2008-01-29	2009-07-30	Confluent Surgical, Inc.	Bioabsorbable block copolymer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE53166B1 (en) *	1980-08-05	1988-08-03	Searle & Co	Synthetic urogastrone gene,corresponding plasmid recombinants,transformed cells,production thereof and urogastrone expression

1983
- 1983-05-02 WO PCT/US1983/000650 patent/WO1983004030A1/en unknown
- 1983-05-02 EP EP83901992A patent/EP0108132A1/en not_active Withdrawn
- 1983-05-04 CA CA000427372A patent/CA1214739A/en not_active Expired
- 1983-05-06 IT IT8367501A patent/IT1212984B/en active

Also Published As

Publication number	Publication date
IT8367501A0 (en)	1983-05-06
EP0108132A1 (en)	1984-05-16
WO1983004030A1 (en)	1983-11-24
CA1214739A (en)	1986-12-02

Publication	Publication Date	Title
IT1212984B (en)	1989-12-07	MANUFACTURE AND EXPRESSION OF GENES FOR UROGASTRONE AND ITS POLYPEPTIDAL ANALOGUES
IT1212983B (en)	1989-12-07	MANUFACTURE AND EXPRESSION OF STRUCTURAL GENES
IT8367500A0 (en)	1983-05-06	MANUFACTURING AND EXPRESSION OF LARGE STRUCTURAL GENES
IT1134130B (en)	1986-07-24	ANALOGS OF 7-OSSABICICLOEPTANO AND 7-OSSABICICLOEPTENE PROSTAGLANDINA
GB8314985D0 (en)	1983-07-06	Drive-belts of trapezoidal cross-section
FI834345A0 (en)	1983-11-28	TETRAPEPTIDER OF SUBSTITUTES
IT1138138B (en)	1986-09-17	ISOMERIZATION OF 2-METHYL-3-BUTEN-NITRILE
IT1212981B (en)	1989-12-07	MANUFACTURE AND EXPRESSION OF GENES FOR CALCITONIN AND ITS POLYPEPTIDAL ANALOGUES
JPS56130307A (en)	1981-10-13	Manufacture of ceramic structure
IT8348304A0 (en)	1983-05-16	TREATMENT PROCEDURE OF A POLYMORISATION REACTOR
IT1164189B (en)	1987-04-08	ANALOGUES OF VASOLOGHI DELLA VASOPRESSINA
IT1173654B (en)	1987-06-24	USE OF COLECALCIFEROL-DERIVATIVES
JPS56135098A (en)	1981-10-22	Structure of polygonal pen point
TR22560A (en)	1987-10-23	TUEREVLER OF SULFONILGUANIDINOPIRIMID
ZA81987B (en)	1982-03-31	Combinations of agents which give enhanced anti-inflammatory activity
DE3361290D1 (en)	1986-01-02	PREPARATION OF CYANOBENZOIC-ACID ESTERS
IT1160840B (en)	1987-03-11	SERIAL NUMBERING METHOD OF ELONGATED ELEMENTS
IT1171672B (en)	1987-06-10	USE OF A COLECALCIFEROLDERIVATO
JPS56119005A (en)	1981-09-18	Construction of elevated structure
JPS54112899A (en)	1979-09-04	Carbamate of monorecelgol
JPS57108363A (en)	1982-07-06	Execution of concrete structure
IT8222515A1 (en)	1984-01-22	New esters of epinine
JPS56119004A (en)	1981-09-18	Construction of elevated structure
JPS56131705A (en)	1981-10-15	Construction of elevated structure
FI833281A (en)	1983-09-14	DIAZADERIVES OF THREE SUBSTITUTES