IT1212502B - Intermedi per la produzione di picropodofillina e composti relativi, e procedimenti per laloro preparazione e il loro uso. - Google Patents
Intermedi per la produzione di picropodofillina e composti relativi, e procedimenti per laloro preparazione e il loro uso.Info
- Publication number
- IT1212502B IT1212502B IT8120148A IT2014881A IT1212502B IT 1212502 B IT1212502 B IT 1212502B IT 8120148 A IT8120148 A IT 8120148A IT 2014881 A IT2014881 A IT 2014881A IT 1212502 B IT1212502 B IT 1212502B
- Authority
- IT
- Italy
- Prior art keywords
- picropodophylline
- intermediates
- procedures
- preparation
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/127,436 US4294763A (en) | 1980-03-05 | 1980-03-05 | Intermediates for the production of picropodophyllin and related compounds and processes for the preparation and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8120148A0 IT8120148A0 (it) | 1981-03-05 |
| IT1212502B true IT1212502B (it) | 1989-11-22 |
Family
ID=22430103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8120148A IT1212502B (it) | 1980-03-05 | 1981-03-05 | Intermedi per la produzione di picropodofillina e composti relativi, e procedimenti per laloro preparazione e il loro uso. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4294763A (it) |
| JP (2) | JPS572229A (it) |
| CA (1) | CA1181083A (it) |
| CH (2) | CH655303A5 (it) |
| DE (2) | DE3153681C2 (it) |
| ES (3) | ES500056A0 (it) |
| GB (2) | GB2070609B (it) |
| IT (1) | IT1212502B (it) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4708964A (en) * | 1984-02-09 | 1987-11-24 | Chemex Pharmaceuticals | Lipoxygenase inhibitors |
| US4866189A (en) * | 1985-04-12 | 1989-09-12 | Bristol-Myers Company | Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof |
| US4644072A (en) * | 1985-04-12 | 1987-02-17 | Bristol-Myers Company | Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof |
| US4795819A (en) * | 1985-04-12 | 1989-01-03 | Bristol-Myers Company | Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof |
| US4734512A (en) * | 1985-12-05 | 1988-03-29 | Bristol-Myers Company | Intermediates for the production of podophyllotoxin and related compounds and processes for the preparation and use thereof |
| US5013851A (en) * | 1985-12-05 | 1991-05-07 | Bristol-Myers Company | Intermediates for the production of podophyllotoxin and related compounds |
| US5106996A (en) * | 1985-12-05 | 1992-04-21 | Bristol-Myers Company | Process for the preparation of podophyllotoxin |
| US20030129186A1 (en) | 2001-07-25 | 2003-07-10 | Biomarin Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| SI1889198T1 (sl) | 2005-04-28 | 2015-02-27 | Proteus Digital Health, Inc. | Farma-informacijski sistem |
| EP2063905B1 (en) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| WO2009100349A1 (en) * | 2008-02-09 | 2009-08-13 | The Trustees Of Columbia University In The City Of New York | Analogues of (-)-picropodophyllin, synthesis and uses thereof |
| DK2398500T3 (da) | 2009-02-20 | 2019-05-13 | 2 Bbb Medicines B V | Glutathion-baseret lægemiddelafgivelsessystem |
| ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6613143A (it) * | 1965-09-21 | 1967-03-22 | ||
| US4122092A (en) * | 1977-08-25 | 1978-10-24 | University Of Rochester | Total synthesis of (±)-picropodophyllone and (±)-4'-demethylpicropodophyllone |
-
1980
- 1980-03-05 US US06/127,436 patent/US4294763A/en not_active Expired - Lifetime
-
1981
- 1981-02-23 DE DE3153681A patent/DE3153681C2/de not_active Expired - Fee Related
- 1981-02-23 DE DE19813106674 patent/DE3106674A1/de active Granted
- 1981-02-27 CH CH1350/81A patent/CH655303A5/de not_active IP Right Cessation
- 1981-02-27 CH CH5351/84A patent/CH657363A5/de not_active IP Right Cessation
- 1981-03-02 JP JP2978981A patent/JPS572229A/ja active Granted
- 1981-03-03 CA CA000372161A patent/CA1181083A/en not_active Expired
- 1981-03-04 ES ES500056A patent/ES500056A0/es active Granted
- 1981-03-04 GB GB8106755A patent/GB2070609B/en not_active Expired
- 1981-03-04 ES ES500055A patent/ES500055A0/es active Granted
- 1981-03-04 ES ES500051A patent/ES500051A0/es active Granted
- 1981-03-05 IT IT8120148A patent/IT1212502B/it active
-
1983
- 1983-03-28 GB GB08308455A patent/GB2116182B/en not_active Expired
-
1988
- 1988-07-05 JP JP88167623A patent/JPH01199929A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GB2116182B (en) | 1984-10-31 |
| ES8205407A1 (es) | 1982-06-01 |
| DE3153681C2 (it) | 1992-07-09 |
| ES8205406A1 (es) | 1982-06-01 |
| GB2116182A (en) | 1983-09-21 |
| GB8308455D0 (en) | 1983-05-05 |
| ES500056A0 (es) | 1982-06-01 |
| DE3106674A1 (de) | 1981-12-17 |
| IT8120148A0 (it) | 1981-03-05 |
| US4294763A (en) | 1981-10-13 |
| ES500055A0 (es) | 1982-06-01 |
| CA1181083A (en) | 1985-01-15 |
| GB2070609A (en) | 1981-09-09 |
| CH655303A5 (de) | 1986-04-15 |
| ES8205408A1 (es) | 1982-06-01 |
| JPH01199929A (ja) | 1989-08-11 |
| GB2070609B (en) | 1984-08-08 |
| JPS572229A (en) | 1982-01-07 |
| ES500051A0 (es) | 1982-06-01 |
| DE3106674C2 (it) | 1992-06-11 |
| JPH0148272B2 (it) | 1989-10-18 |
| CH657363A5 (de) | 1986-08-29 |
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