IT1176322B - Estere dell'acido (+) 6-metossi-alfa-metil-2-naftalenacetico avnete attivita' mucosecretolitica,antinfiammatoria,analgesica,antiprietica,procedimento per la sua preparazione e sue composizioni farmaceutiche - Google Patents
Estere dell'acido (+) 6-metossi-alfa-metil-2-naftalenacetico avnete attivita' mucosecretolitica,antinfiammatoria,analgesica,antiprietica,procedimento per la sua preparazione e sue composizioni farmaceuticheInfo
- Publication number
- IT1176322B IT1176322B IT21609/84A IT2160984A IT1176322B IT 1176322 B IT1176322 B IT 1176322B IT 21609/84 A IT21609/84 A IT 21609/84A IT 2160984 A IT2160984 A IT 2160984A IT 1176322 B IT1176322 B IT 1176322B
- Authority
- IT
- Italy
- Prior art keywords
- ester
- methoxy
- methyl
- mucosecretolytic
- activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
- C07C69/616—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety polycyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21609/84A IT1176322B (it) | 1984-06-26 | 1984-06-26 | Estere dell'acido (+) 6-metossi-alfa-metil-2-naftalenacetico avnete attivita' mucosecretolitica,antinfiammatoria,analgesica,antiprietica,procedimento per la sua preparazione e sue composizioni farmaceutiche |
AT85105644T ATE43964T1 (de) | 1984-06-26 | 1985-05-08 | Ester der (+)-6-methoxy-alpha-methyl-2naphthalenessigs|ure mit mucosekretolytischer, entzuendungshemmender, schmerzstillender, fieber erniedrigender wirkung, dessen herstellungsverfahren und dessen pharmazeutische zusammensetzungen. |
DE8585105644T DE3570979D1 (en) | 1984-06-26 | 1985-05-08 | An ester of (+)6-methoxy- alpha -methyl-2-naphtalene acetic acid having mucosecretolytic, anti-inflammatory, analgesic, antipyretic activity, a process for its preparation and pharmaceutical compositions thereof |
EP85105644A EP0166135B1 (en) | 1984-06-26 | 1985-05-08 | An ester of (+)6-methoxy- alpha -methyl-2-naphtalene acetic acid having mucosecretolytic, anti-inflammatory, analgesic, antipyretic activity, a process for its preparation and pharmaceutical compositions thereof |
US06/734,068 US4665224A (en) | 1984-06-26 | 1985-05-15 | Ester of (+) 6-methoxy-α-methyl-2-naphthalene acetic acid having mucosecretolytic, anti-inflammatory, analgesic, antipyretic activity, a process for its preparation and pharmaceutical compositions thereof |
KR1019850004511A KR870000276A (ko) | 1984-06-26 | 1985-06-25 | (+)6-메톡시-α-메틸-2-나프탈렌 아세트산의 에스테르 제조방법 |
JP60137080A JPS6118746A (ja) | 1984-06-26 | 1985-06-25 | (+)6‐メトキシ‐α‐メチル‐2‐ナフタレン酢酸エステル,その製法,および医薬組成物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21609/84A IT1176322B (it) | 1984-06-26 | 1984-06-26 | Estere dell'acido (+) 6-metossi-alfa-metil-2-naftalenacetico avnete attivita' mucosecretolitica,antinfiammatoria,analgesica,antiprietica,procedimento per la sua preparazione e sue composizioni farmaceutiche |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8421609A0 IT8421609A0 (it) | 1984-06-26 |
IT1176322B true IT1176322B (it) | 1987-08-18 |
Family
ID=11184278
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT21609/84A IT1176322B (it) | 1984-06-26 | 1984-06-26 | Estere dell'acido (+) 6-metossi-alfa-metil-2-naftalenacetico avnete attivita' mucosecretolitica,antinfiammatoria,analgesica,antiprietica,procedimento per la sua preparazione e sue composizioni farmaceutiche |
Country Status (7)
Country | Link |
---|---|
US (1) | US4665224A (it) |
EP (1) | EP0166135B1 (it) |
JP (1) | JPS6118746A (it) |
KR (1) | KR870000276A (it) |
AT (1) | ATE43964T1 (it) |
DE (1) | DE3570979D1 (it) |
IT (1) | IT1176322B (it) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4912248A (en) * | 1987-05-18 | 1990-03-27 | The Procter & Gamble Company | Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation |
US5792886A (en) * | 1997-01-08 | 1998-08-11 | Albemarle Corporation | Production of racemic 2-(6-methoxy-2-naphthyl) propionic acid of precursors thereof |
US6080888A (en) * | 1997-01-08 | 2000-06-27 | Albemarle Corporation | Preparation of olefinic compounds and carboxylic derivatives thereof |
US6096920A (en) * | 1997-01-08 | 2000-08-01 | Albemarle Corporation | Preparation of carboxylic compounds and their derivatives |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4048330A (en) * | 1967-01-13 | 1977-09-13 | Syntex Corporation | Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia |
US3904682A (en) * | 1967-01-13 | 1975-09-09 | Syntex Corp | 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid |
ZA701191B (en) * | 1969-03-24 | 1971-09-29 | Syntex Corp | 2-(6-substituted-2'-naphthyl)acetic acid esters and process for producing same |
IT1190663B (it) * | 1982-01-21 | 1988-02-24 | Ausonia Farma Srl | Composto ad attivita' antiinfiammatoria,analgesica e mucoregolatrice,procedimento per la sua preparazione e relative composizioni farmaceutiche |
DE3360037D1 (en) * | 1982-04-15 | 1985-02-07 | Firmenich & Cie | 1(7)p-menthene-9-al and its use as a perfuming and flavouring agent |
-
1984
- 1984-06-26 IT IT21609/84A patent/IT1176322B/it active
-
1985
- 1985-05-08 AT AT85105644T patent/ATE43964T1/de not_active IP Right Cessation
- 1985-05-08 DE DE8585105644T patent/DE3570979D1/de not_active Expired
- 1985-05-08 EP EP85105644A patent/EP0166135B1/en not_active Expired
- 1985-05-15 US US06/734,068 patent/US4665224A/en not_active Expired - Fee Related
- 1985-06-25 KR KR1019850004511A patent/KR870000276A/ko not_active Application Discontinuation
- 1985-06-25 JP JP60137080A patent/JPS6118746A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0166135B1 (en) | 1989-06-14 |
ATE43964T1 (de) | 1989-06-15 |
KR870000276A (ko) | 1987-02-17 |
DE3570979D1 (en) | 1989-07-20 |
EP0166135A2 (en) | 1986-01-02 |
IT8421609A0 (it) | 1984-06-26 |
EP0166135A3 (en) | 1986-06-11 |
US4665224A (en) | 1987-05-12 |
JPS6118746A (ja) | 1986-01-27 |
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