IT1171879B - Derivati di 2-ammino-3-acilammino-6-benzilammino-piridina aventi azione antiepilettica - Google Patents
Derivati di 2-ammino-3-acilammino-6-benzilammino-piridina aventi azione antiepiletticaInfo
- Publication number
- IT1171879B IT1171879B IT49222/83A IT4922283A IT1171879B IT 1171879 B IT1171879 B IT 1171879B IT 49222/83 A IT49222/83 A IT 49222/83A IT 4922283 A IT4922283 A IT 4922283A IT 1171879 B IT1171879 B IT 1171879B
- Authority
- IT
- Italy
- Prior art keywords
- group
- antiepileeptic
- acylamin
- benzylamine
- pyridin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3239790 | 1982-10-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8349222A0 IT8349222A0 (it) | 1983-10-26 |
IT1171879B true IT1171879B (it) | 1987-06-10 |
Family
ID=6176726
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT49223/83A IT1171880B (it) | 1982-10-27 | 1983-10-26 | Derivati di 2-ammino-3-acilammino-6-benzilammino-piridina aventi azione antiepilettica e procedimento per la loro produzione |
IT49222/83A IT1171879B (it) | 1982-10-27 | 1983-10-26 | Derivati di 2-ammino-3-acilammino-6-benzilammino-piridina aventi azione antiepilettica |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT49223/83A IT1171880B (it) | 1982-10-27 | 1983-10-26 | Derivati di 2-ammino-3-acilammino-6-benzilammino-piridina aventi azione antiepilettica e procedimento per la loro produzione |
Country Status (8)
Country | Link |
---|---|
US (1) | US4554281A (it) |
EP (1) | EP0110091B1 (it) |
JP (2) | JPS5995270A (it) |
AT (1) | ATE25078T1 (it) |
AU (1) | AU561450B2 (it) |
DE (1) | DE3369315D1 (it) |
ES (1) | ES8406440A1 (it) |
IT (2) | IT1171880B (it) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0189788B1 (de) * | 1985-01-23 | 1989-09-13 | ASTA Pharma Aktiengesellschaft | Synergistische Kombination von Flupirtin und nicht-steroidalen Antiphlogistika |
NO860825L (no) * | 1985-03-23 | 1986-09-24 | Degussa | Fremgangsmaate til fremstilling av 2-amino-3-nitro-6-(4-fluor-benzylamino)-pyridin samt 2-amino-3-karbetoksyamino-6-(4-fluor-benzylamino)-pyridin. |
DE4327516A1 (de) * | 1993-08-17 | 1995-02-23 | Asta Medica Ag | Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin |
ZA953078B (en) * | 1994-04-28 | 1996-01-05 | Alza Corp | Effective therapy for epilepsies |
US20040191314A1 (en) * | 1994-04-28 | 2004-09-30 | Frank Jao | Antiepileptic dosage form and process for protecting antiepileptic drug |
DE19835918A1 (de) * | 1998-08-07 | 2000-02-10 | Dresden Arzneimittel | Neue antikonvulsiv wirkende 4-Amino-1-aryl-pyridin-2-one und Verfahren zu deren Herstellung |
US7799832B2 (en) * | 2003-10-23 | 2010-09-21 | Valeant Pharmaceuticals North America | Combinations of retigabine and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains |
US20080287399A1 (en) * | 2004-12-14 | 2008-11-20 | Astrazeneca Ab | Substituted Aminopyridines and Uses Thereof |
US7960436B2 (en) * | 2006-06-05 | 2011-06-14 | Valeant Pharmaceuticals International | Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators |
SG174095A1 (en) * | 2006-08-23 | 2011-09-29 | Valeant Pharmaceuticals Int | Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators |
US8993593B2 (en) * | 2006-08-23 | 2015-03-31 | Valeant Pharmaceuticals International | N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators |
US8722929B2 (en) * | 2006-10-10 | 2014-05-13 | Valeant Pharmaceuticals International | N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators |
BRPI0719590A2 (pt) * | 2006-11-28 | 2014-01-21 | Valeant Pharmaceuticals Int | Análogos de retigabina 1,4 diamino bicíclica como modulares de canal de potássio |
US8367684B2 (en) * | 2007-06-13 | 2013-02-05 | Valeant Pharmaceuticals International | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
US8563566B2 (en) | 2007-08-01 | 2013-10-22 | Valeant Pharmaceuticals International | Naphthyridine derivatives as potassium channel modulators |
JP2009037141A (ja) | 2007-08-03 | 2009-02-19 | Ricoh Co Ltd | 画像形成装置の管理装置及び管理システム |
US7786146B2 (en) * | 2007-08-13 | 2010-08-31 | Valeant Pharmaceuticals International | Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators |
WO2009074592A1 (en) * | 2007-12-11 | 2009-06-18 | Neurosearch A/S | Novel 2-diethylamino-3-amido-6-amino-pyridine derivatives useful as potassium channel activators |
JP2011506388A (ja) * | 2007-12-11 | 2011-03-03 | ノイロサーチ アクティーゼルスカブ | カリウムチャネル活性化因子として有用な、新規の2−ジメチルアミノ−3−アミド−6−アミノ−ピリジン誘導体 |
EP2231609A1 (en) * | 2007-12-11 | 2010-09-29 | NeuroSearch A/S | Novel 2-ethyl-methyl-amino-3-amido-6-amino-pyridine derivatives useful as potassium channel activators |
WO2009074593A1 (en) * | 2007-12-11 | 2009-06-18 | Neurosearch A/S | Novel 2-pyrrolidinyl-3-amido-6-amino-pyridine derivatives useful as potassium channel activators |
CN102351786A (zh) * | 2011-11-01 | 2012-02-15 | 东南大学 | 一种氟吡汀丙二酸盐及其制备方法 |
US11369593B2 (en) | 2017-07-14 | 2022-06-28 | Texas Tech University System | Functionalized pyridine carbamates with enhanced neuroprotective activity |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670522C3 (de) * | 1966-05-12 | 1978-08-31 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt | Neue Benzylaminopyridine |
BE764362R (en) * | 1966-05-12 | 1971-09-16 | Degussa | Subst amino pyridienes production |
JPS5541411B2 (it) * | 1973-04-28 | 1980-10-24 |
-
1983
- 1983-10-18 EP EP83110360A patent/EP0110091B1/de not_active Expired
- 1983-10-18 AT AT83110360T patent/ATE25078T1/de active
- 1983-10-18 DE DE8383110360T patent/DE3369315D1/de not_active Expired
- 1983-10-25 JP JP58198412A patent/JPS5995270A/ja active Pending
- 1983-10-25 JP JP58198411A patent/JPS5995269A/ja active Granted
- 1983-10-26 ES ES526765A patent/ES8406440A1/es not_active Expired
- 1983-10-26 IT IT49223/83A patent/IT1171880B/it active
- 1983-10-26 IT IT49222/83A patent/IT1171879B/it active
- 1983-10-26 AU AU20582/83A patent/AU561450B2/en not_active Ceased
- 1983-10-27 US US06/545,930 patent/US4554281A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES526765A0 (es) | 1984-07-01 |
JPH0144170B2 (it) | 1989-09-26 |
EP0110091A1 (de) | 1984-06-13 |
EP0110091B1 (de) | 1987-01-21 |
US4554281A (en) | 1985-11-19 |
AU2058283A (en) | 1984-05-03 |
ES8406440A1 (es) | 1984-07-01 |
JPS5995269A (ja) | 1984-06-01 |
IT1171880B (it) | 1987-06-10 |
AU561450B2 (en) | 1987-05-07 |
JPS5995270A (ja) | 1984-06-01 |
DE3369315D1 (en) | 1987-02-26 |
ATE25078T1 (de) | 1987-02-15 |
IT8349222A0 (it) | 1983-10-26 |
IT8349223A0 (it) | 1983-10-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IT1171879B (it) | Derivati di 2-ammino-3-acilammino-6-benzilammino-piridina aventi azione antiepilettica | |
ATE24001T1 (de) | Substituierte 1-hydroxyethyl-triazolyl-derivate. | |
ZA876345B (en) | Phenolic corrosion inhibitors for coating materials | |
DE3360904D1 (de) | A fungicidal indanylbenzamide | |
DE3266708D1 (en) | Pyridazinone derivatives, process for their preparation and their use as fungicides | |
FI812804L (fi) | 2-(1,4-bensodioxan-2-ylalkyl)-imidazoler anvaendbara som antidepressiva laekemedel | |
ZA824813B (en) | Pyridinecarbinols,their preparation and fungicides containing these compounds | |
DK428087A (da) | Dihydropyridin-5-phosphonsyre-cyclopropylenester | |
ZA8312B (en) | Substituted 1-benzoyl-2-phenyliminiomidazolidine derivatives | |
DE3168178D1 (en) | 2-(n-aryl-n-1,2,3-thiadiazolyl-carbonyl)-aminobutyrolactones, their preparation, fungicides containing them and their use as fungicides | |
DE3270999D1 (de) | N-substituted-tetrahydroisophthalimide derivatives | |
ES544712A0 (es) | Procedimiento para la obtencion de iminosulfonamidas | |
ATE26275T1 (de) | Acridanon-derivate. | |
ES519917A0 (es) | Procedimiento para la obtencion de oximinoacetanilidas sustituidas. | |
ES532177A0 (es) | Procedimiento para preparar nuevas semicarbazidas |