IT1169013B - Composti macrolidici ad attivita' antibiotica, procedimento e microorganismo per la loro preparazione e relative composizioni farmaceutiche - Google Patents

Composti macrolidici ad attivita' antibiotica, procedimento e microorganismo per la loro preparazione e relative composizioni farmaceutiche

Info

Publication number
IT1169013B
IT1169013B IT8119081A IT1908181A IT1169013B IT 1169013 B IT1169013 B IT 1169013B IT 8119081 A IT8119081 A IT 8119081A IT 1908181 A IT1908181 A IT 1908181A IT 1169013 B IT1169013 B IT 1169013B
Authority
IT
Italy
Prior art keywords
macrolidic
microorganism
compounds
procedure
preparation
Prior art date
Application number
IT8119081A
Other languages
English (en)
Other versions
IT8119081A0 (it
Inventor
Leonardo Cappelletti
Roberto Spagnoli
Luciano Toscano
Original Assignee
Pierrel Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierrel Spa filed Critical Pierrel Spa
Publication of IT8119081A0 publication Critical patent/IT8119081A0/it
Priority to IT8119081A priority Critical patent/IT1169013B/it
Priority to BE0/207018A priority patent/BE891733A/fr
Priority to FR8200188A priority patent/FR2502156B1/fr
Priority to DE8282200016T priority patent/DE3268903D1/de
Priority to FI820056A priority patent/FI72743C/fi
Priority to AT82200016T priority patent/ATE17855T1/de
Priority to EP82200016A priority patent/EP0056290B1/en
Priority to CH97/82A priority patent/CH663034A5/it
Priority to CA000393823A priority patent/CA1177427A/en
Priority to US06/338,117 priority patent/US4429115A/en
Priority to JP57002181A priority patent/JPS57138384A/ja
Priority to US06/548,323 priority patent/US4560662A/en
Application granted granted Critical
Publication of IT1169013B publication Critical patent/IT1169013B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/48—Streptomyces antibioticus ; Actinomyces antibioticus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y10S435/888—Streptomyces antibioticus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IT8119081A 1981-01-09 1981-01-09 Composti macrolidici ad attivita' antibiotica, procedimento e microorganismo per la loro preparazione e relative composizioni farmaceutiche IT1169013B (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT8119081A IT1169013B (it) 1981-01-09 1981-01-09 Composti macrolidici ad attivita' antibiotica, procedimento e microorganismo per la loro preparazione e relative composizioni farmaceutiche
EP82200016A EP0056290B1 (en) 1981-01-09 1982-01-08 Novel macrolidic antibiotics having antibiotic activity, process and microorganism for their preparation, and related pharmaceutical compositions
FR8200188A FR2502156B1 (fr) 1981-01-09 1982-01-08 Nouveaux composes macrolides a activite antibiotique, procede et micro-organismes pour leur preparation, et compositions pharmaceutiques correspondantes
DE8282200016T DE3268903D1 (en) 1981-01-09 1982-01-08 Novel macrolidic antibiotics having antibiotic activity, process and microorganism for their preparation, and related pharmaceutical compositions
FI820056A FI72743C (fi) 1981-01-09 1982-01-08 Foerfarande foer framstaellning av nya makrolidantibiotika.
AT82200016T ATE17855T1 (de) 1981-01-09 1982-01-08 Makrolide verbindungen mit antibiotischer wirkung, verfahren und mikroorganismen zu ihrer herstellung und pharmazeutische zusammensetzungen.
BE0/207018A BE891733A (fr) 1981-01-09 1982-01-08 Nouveaux composes macrolides a activite antibiotique, procede et micro-organismes pour leur preparation, et compositions pharmaceutiques correspondantes
CH97/82A CH663034A5 (it) 1981-01-09 1982-01-08 Composti macrolidici ad attivita antibiotica, procedimento e microorganismo per la loro preparazione, e relative composizioni farmaceutiche.
CA000393823A CA1177427A (en) 1981-01-09 1982-01-08 Macrolidic antibiotics having antibiotic activity process and microorganism for their preparation and related pharmaceutical compositions
US06/338,117 US4429115A (en) 1981-01-09 1982-01-08 3-O-Oleandrosyl-5-O-desosaminyl erythronolide compounds
JP57002181A JPS57138384A (en) 1981-01-09 1982-01-09 New macrolide compound, preparation thereof and microorganism using and producing same
US06/548,323 US4560662A (en) 1981-01-09 1983-11-03 Streptomyces antibioticus ATCC 31771 and process for obtaining same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8119081A IT1169013B (it) 1981-01-09 1981-01-09 Composti macrolidici ad attivita' antibiotica, procedimento e microorganismo per la loro preparazione e relative composizioni farmaceutiche

Publications (2)

Publication Number Publication Date
IT8119081A0 IT8119081A0 (it) 1981-01-09
IT1169013B true IT1169013B (it) 1987-05-20

Family

ID=11154383

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8119081A IT1169013B (it) 1981-01-09 1981-01-09 Composti macrolidici ad attivita' antibiotica, procedimento e microorganismo per la loro preparazione e relative composizioni farmaceutiche

Country Status (11)

Country Link
US (2) US4429115A (it)
EP (1) EP0056290B1 (it)
JP (1) JPS57138384A (it)
AT (1) ATE17855T1 (it)
BE (1) BE891733A (it)
CA (1) CA1177427A (it)
CH (1) CH663034A5 (it)
DE (1) DE3268903D1 (it)
FI (1) FI72743C (it)
FR (1) FR2502156B1 (it)
IT (1) IT1169013B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI72346C (fi) * 1981-01-09 1987-05-11 Pierrel Spa Saett att framstaella nya halvsyntetiska makrolidantibiotika.
US5149639A (en) * 1986-03-24 1992-09-22 Abbott Laboratories Biologically pure cultures of streptomyces and use thereof in macrolide antibiotic production
CA2411293A1 (en) * 1999-01-28 2000-07-28 Pfizer Products Inc. Novel azalides and methods of making same
GB0327720D0 (en) 2003-11-28 2003-12-31 Biotica Tech Ltd Erythromycins and process for their preparation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA564945A (en) * 1958-10-21 Walter L. Clifton, Jr. Door hinge
US3697547A (en) * 1970-12-18 1972-10-10 Abbott Lab Erythronolide b derivatives
BE793112A (fr) * 1971-12-22 1973-06-21 Ciba Geigy Pyridinium-s-triazines agissant sur la croissance des plantes
US3855200A (en) * 1973-04-23 1974-12-17 Polska Akademia Nauk Instytut Process for preparing 8-hydroxyerthromycin a and intermediates therefor
US3992264A (en) * 1974-02-04 1976-11-16 Hoffmann-La Roche Inc. Antibiotic 1745A/X and methods for the production thereof
US4152424A (en) * 1975-07-23 1979-05-01 Hoffmann-La Roche Inc. Antibiotic 1745A/X and methods for the production thereof
US4069379A (en) 1976-07-08 1978-01-17 Pfizer Inc. Semi-synthetic oleandomycins
US4036853A (en) 1976-08-06 1977-07-19 Pfizer Inc. Semi-synthetic oleandomycin derivatives-C8 modifications
US4085119A (en) 1977-02-04 1978-04-18 Pfizer Inc. 4-Substituted amino derivatives of oleandomycin

Also Published As

Publication number Publication date
EP0056290B1 (en) 1986-02-05
CH663034A5 (it) 1987-11-13
FI72743C (fi) 1987-07-10
EP0056290A2 (en) 1982-07-21
FI72743B (fi) 1987-03-31
FI820056L (fi) 1982-07-10
US4560662A (en) 1985-12-24
JPS57138384A (en) 1982-08-26
EP0056290A3 (en) 1983-01-12
IT8119081A0 (it) 1981-01-09
ATE17855T1 (de) 1986-02-15
CA1177427A (en) 1984-11-06
FR2502156A1 (fr) 1982-09-24
FR2502156B1 (fr) 1986-10-31
BE891733A (fr) 1982-04-30
US4429115A (en) 1984-01-31
DE3268903D1 (en) 1986-03-20
JPH0365944B2 (it) 1991-10-15

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