IT1166483B - Derivati del 2 fenilimidazo 2 1 b benzotiazolo aventi un effetto immunoregolatorio e procedimento per la loro preparazione - Google Patents

Derivati del 2 fenilimidazo 2 1 b benzotiazolo aventi un effetto immunoregolatorio e procedimento per la loro preparazione

Info

Publication number
IT1166483B
IT1166483B IT68303/80A IT6830380A IT1166483B IT 1166483 B IT1166483 B IT 1166483B IT 68303/80 A IT68303/80 A IT 68303/80A IT 6830380 A IT6830380 A IT 6830380A IT 1166483 B IT1166483 B IT 1166483B
Authority
IT
Italy
Prior art keywords
fenylimidazo
benzothiazole
derivatives
procedure
preparation
Prior art date
Application number
IT68303/80A
Other languages
English (en)
Other versions
IT8068303A0 (it
Inventor
Murase Kiyoshi
Mase Toshiyasu
Tomioka Kenichi
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10643879A external-priority patent/JPS5630990A/ja
Priority claimed from JP14507779A external-priority patent/JPS5668685A/ja
Priority claimed from JP14844179A external-priority patent/JPS5671096A/ja
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of IT8068303A0 publication Critical patent/IT8068303A0/it
Application granted granted Critical
Publication of IT1166483B publication Critical patent/IT1166483B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IT68303/80A 1979-08-21 1980-08-20 Derivati del 2 fenilimidazo 2 1 b benzotiazolo aventi un effetto immunoregolatorio e procedimento per la loro preparazione IT1166483B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10643879A JPS5630990A (en) 1979-08-21 1979-08-21 2-phenylimidazo 2,1-b benzothiazole derivative and its preparation
JP14507779A JPS5668685A (en) 1979-11-09 1979-11-09 2-phenylimidazo 2,1-b benzothiazole derivative and its preparation
JP14844179A JPS5671096A (en) 1979-11-16 1979-11-16 2-phenylimidazo 2,1-b- benzothiazole derivative

Publications (2)

Publication Number Publication Date
IT8068303A0 IT8068303A0 (it) 1980-08-20
IT1166483B true IT1166483B (it) 1987-05-06

Family

ID=27310731

Family Applications (1)

Application Number Title Priority Date Filing Date
IT68303/80A IT1166483B (it) 1979-08-21 1980-08-20 Derivati del 2 fenilimidazo 2 1 b benzotiazolo aventi un effetto immunoregolatorio e procedimento per la loro preparazione

Country Status (8)

Country Link
US (1) US4497817A (it)
AT (1) ATA425280A (it)
CA (1) CA1158246A (it)
DE (1) DE3030982A1 (it)
ES (1) ES494397A0 (it)
FR (1) FR2463774A1 (it)
GB (1) GB2056982B (it)
IT (1) IT1166483B (it)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464384A (en) * 1981-12-23 1984-08-07 Yamanouchi Pharmaceutical Co., Ltd. 2-Phenylimidazo[2,1-b]benzothiazole compounds, salts thereof, process of producing them, and pharmaceutical compositions containing them
JP2726999B2 (ja) * 1988-06-22 1998-03-11 日研化学株式会社 イミダゾ［２，１−ｂ］ベンゾチアゾール誘導体及び該化合物を有効成分とする抗潰瘍剤
IT1243362B (it) * 1990-07-25 1994-06-10 Pietro Monforte Sintesi di attivita' anti-hiv di 1h, 3h-tiazolo 3,4-a benzimidazoli 1-sostituiti
EP0816366A4 (en) * 1995-03-13 1998-07-08 Nikken Chemicals Co Ltd IMIDAZOTHIAZOL COMPOUNDS
AU3783497A (en) * 1996-08-09 1998-03-06 Yamanouchi Pharmaceutical Co., Ltd. Metabotropic glutamate receptor agonists
US6127387A (en) * 1996-12-10 2000-10-03 Thomas Jefferson University Use of CD4-binding small molecules to inhibit immune responses
ATE380548T1 (de) * 1999-01-29 2007-12-15 Univ Illinois Verwendung von p53 inhibitoren zur behandlung von nebenerscheinungen bei der krebstherapie
DE19948434A1 (de) * 1999-10-08 2001-06-07 Gruenenthal Gmbh Substanzbibliothek enthaltend bicyclische Imidazo-5-amine und/oder bicyclische Imidazo-3-amine
DE19948436B4 (de) * 1999-10-08 2006-11-16 Grünenthal GmbH Bicyclische Imidazo-5-aminderivate
US6867299B2 (en) 2000-02-24 2005-03-15 Hoffmann-La Roche Inc. Oxamide IMPDH inhibitors
US7601846B2 (en) * 2001-06-26 2009-10-13 The Regents Of The University Of California Compounds having activity as inhibitors of apoptosis
DE10150172A1 (de) * 2001-10-11 2003-04-30 Morphochem Ag Neue Verbindungen, die Protein Tyrosin Phosphatase 1B (PTP-1B) inhibieren
MX2007003795A (es) * 2004-09-28 2007-07-11 Quark Biotech Inc Oligoribonucleotidos y metodos de uso de los mismos para tratamiento de la alopecia, insuficiencia renal aguda y otras enfermedades.
US7825099B2 (en) * 2006-01-20 2010-11-02 Quark Pharmaceuticals, Inc. Treatment or prevention of oto-pathologies by inhibition of pro-apoptotic genes
US7910566B2 (en) * 2006-03-09 2011-03-22 Quark Pharmaceuticals Inc. Prevention and treatment of acute renal failure and other kidney diseases by inhibition of p53 by siRNA
CN101448843B (zh) * 2006-03-17 2012-05-09 埃姆比特生物科学公司 用于疾病治疗的咪唑并噻唑化合物
US8785408B2 (en) * 2007-06-27 2014-07-22 Quark Pharmaceuticals, Inc. Compositions and methods for reducing or protecting against delayed graft function (DGF)
US8883783B2 (en) * 2007-09-19 2014-11-11 Ambit Biosciences Corporation Solid forms comprising N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions thereof, and uses therewith
EP2218464A1 (en) * 2009-02-11 2010-08-18 Technische Universität München Compounds for non-invasive measurement of aggregates of amyloid peptides
CN107417705B (zh) * 2017-07-24 2019-07-02 湘潭大学 咪唑并[2,1-b]苯并噻唑类化合物及其合成方法
IL279972A (en) * 2021-01-05 2022-08-01 Anima Biotech Inc Substances that function as modulators of cmyc-mrna translation and their uses in cancer treatment
WO2024010762A1 (en) * 2022-07-03 2024-01-11 Anima Biotech Inc. C-myc mrna translation modulators and uses thereof in the treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129432C (it) * 1964-02-29
US4080339A (en) * 1973-09-20 1978-03-21 Pfizer Inc. Imidazo[2,1-b]thiazole and thiazolo[3,2-a]benzimidazole quaternary salts as hypoglycemic agents and growth promotants
GB1541321A (en) * 1976-03-10 1979-02-28 Metabio 2,3-dihydroimidazo(2,1-b)thiazole derivatives and process for their preparation
US4262004A (en) * 1979-06-21 1981-04-14 Janssen Pharmaceutica, N.V. 2,3-Dihydro-imidazo[2,1-b]benzothiazole compositions to treat depressions

Also Published As

Publication number Publication date
ES8106535A1 (es) 1981-08-01
ATA425280A (de) 1986-01-15
FR2463774A1 (fr) 1981-02-27
CA1158246A (en) 1983-12-06
FR2463774B1 (it) 1983-10-21
GB2056982A (en) 1981-03-25
ES494397A0 (es) 1981-08-01
DE3030982A1 (de) 1981-03-12
US4497817A (en) 1985-02-05
IT8068303A0 (it) 1980-08-20
GB2056982B (en) 1983-11-16

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