IT1142823B - Procedimento per la esterificazione di alfa-aspartil-l-fenilalanina - Google Patents

Procedimento per la esterificazione di alfa-aspartil-l-fenilalanina

Info

Publication number: IT1142823B
Authority: IT; Italy
Prior art keywords: aspartyl; enzyme; phenylalanine; alpha; esterification
Prior art date: 1981-09-17

Application number

IT49313/81A

Other languages

English (en)

Other versions

IT8149313A0 (it

Inventor

Arthur A Davino

Original Assignee

Searle & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-09-17

Filing date

1981-09-17

Publication date

1986-10-15

1981-09-17 Application filed by Searle & Co filed Critical Searle & Co

1981-09-17 Priority to IT49313/81A priority Critical patent/IT1142823B/it

1981-09-17 Publication of IT8149313A0 publication Critical patent/IT8149313A0/it

1986-10-15 Application granted granted Critical

1986-10-15 Publication of IT1142823B publication Critical patent/IT1142823B/it

Links

230000032050 esterification Effects 0.000 title abstract 3
238000005886 esterification reaction Methods 0.000 title abstract 3
YZQCXOFQZKCETR-UWVGGRQHSA-N Asp-Phe Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 YZQCXOFQZKCETR-UWVGGRQHSA-N 0.000 title abstract 2
230000002255 enzymatic effect Effects 0.000 title 1
108090000790 Enzymes Proteins 0.000 abstract 3
102000004190 Enzymes Human genes 0.000 abstract 3
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
108090000371 Esterases Proteins 0.000 abstract 1
COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1
108091005804 Peptidases Proteins 0.000 abstract 1
102000035195 Peptidases Human genes 0.000 abstract 1
MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
108010056079 Subtilisins Proteins 0.000 abstract 1
102000005158 Subtilisins Human genes 0.000 abstract 1
108010051873 alkaline protease Proteins 0.000 abstract 1
125000005907 alkyl ester group Chemical group 0.000 abstract 1
-1 aspartyl ester Chemical class 0.000 abstract 1
125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
150000005690 diesters Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
235000003599 food sweetener Nutrition 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1
125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
229960005190 phenylalanine Drugs 0.000 abstract 1
COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Natural products O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 abstract 1
239000003765 sweetening agent Substances 0.000 abstract 1

Landscapes

Preparation Of Compounds By Using Micro-Organisms (AREA)

IT49313/81A 1981-09-17 1981-09-17 Procedimento per la esterificazione di alfa-aspartil-l-fenilalanina IT1142823B (it)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
IT49313/81A IT1142823B (it)	1981-09-17	1981-09-17	Procedimento per la esterificazione di alfa-aspartil-l-fenilalanina

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT49313/81A IT1142823B (it)	1981-09-17	1981-09-17	Procedimento per la esterificazione di alfa-aspartil-l-fenilalanina

Publications (2)

Publication Number	Publication Date
IT8149313A0 IT8149313A0 (it)	1981-09-17
IT1142823B true IT1142823B (it)	1986-10-15

Family

ID=11270307

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT49313/81A IT1142823B (it)	1981-09-17	1981-09-17	Procedimento per la esterificazione di alfa-aspartil-l-fenilalanina

Country Status (1)

Country	Link
IT (1)	IT1142823B (it)

1981
- 1981-09-17 IT IT49313/81A patent/IT1142823B/it active

Also Published As

Publication number	Publication date
IT8149313A0 (it)	1981-09-17

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Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19970929