IT1078495B - Antibiotici al beta-lattame e procedimento per la loro produzione - Google Patents

Antibiotici al beta-lattame e procedimento per la loro produzione

Info

Publication number
IT1078495B
IT1078495B IT49798/77A IT4979877A IT1078495B IT 1078495 B IT1078495 B IT 1078495B IT 49798/77 A IT49798/77 A IT 49798/77A IT 4979877 A IT4979877 A IT 4979877A IT 1078495 B IT1078495 B IT 1078495B
Authority
IT
Italy
Prior art keywords
beta
procedure
production
lactam antibiotics
lactam
Prior art date
Application number
IT49798/77A
Other languages
English (en)
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19762626558 external-priority patent/DE2626558A1/de
Priority claimed from DE19772712225 external-priority patent/DE2712225A1/de
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Application granted granted Critical
Publication of IT1078495B publication Critical patent/IT1078495B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/48Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
    • C07D499/58Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
    • C07D499/64Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
    • C07D499/68Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT49798/77A 1976-06-14 1977-06-13 Antibiotici al beta-lattame e procedimento per la loro produzione IT1078495B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19762626558 DE2626558A1 (de) 1976-06-14 1976-06-14 Beta-lactamantibiotika und verfahren zu ihrer herstellung
DE19772712225 DE2712225A1 (de) 1977-03-19 1977-03-19 Beta-lactamantibiotika und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
IT1078495B true IT1078495B (it) 1985-05-08

Family

ID=25770568

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49798/77A IT1078495B (it) 1976-06-14 1977-06-13 Antibiotici al beta-lattame e procedimento per la loro produzione

Country Status (8)

Country Link
US (1) US4162314A (it)
JP (1) JPS52153993A (it)
AU (1) AU2550077A (it)
FR (1) FR2355020A1 (it)
IL (1) IL52289A0 (it)
IT (1) IT1078495B (it)
NL (1) NL7706470A (it)
SE (1) SE7706824L (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
JPS5346995A (en) * 1976-10-12 1978-04-27 Sangyo Kagaku Kenkyu Kyokai Antibacterial agents
US4465668A (en) * 1981-02-27 1984-08-14 Asahi Kasei Kogyo Kabushiki Kaisha Method for improving intestinal absorption of cephalosporin derivatives
AT403049B (de) 1995-08-14 1997-10-27 Biochemie Gmbh Abreicherung von 7-adca in 3-vinyl-aca
WO2005046687A1 (en) * 2003-10-30 2005-05-26 Tioga Pharmaceuticals, Inc. Use of selective opiate receptor modulators in the treatment of neuropathy
CA2777234C (en) 2009-10-11 2019-02-26 Rutgers, The State University Of New Jersey Biocompatible polymers for medical devices
US11472918B2 (en) 2012-02-03 2022-10-18 Rutgers, The State University Of New Jersey Polymeric biomaterials derived from phenolic monomers and their medical uses
CA3069030C (en) 2012-02-03 2021-11-16 Rutgers, The State University Of New Jersey Polymeric biomaterials derived from phenolic monomers and their medical uses
EP3237487B1 (en) 2014-12-23 2021-02-17 Rutgers, the State University of New Jersey Biocompatible iodinated diphenol monomers and polymers
US10774030B2 (en) 2014-12-23 2020-09-15 Rutgers, The State University Of New Jersey Polymeric biomaterials derived from phenolic monomers and their medical uses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985741A (en) * 1972-09-15 1976-10-12 Bristol-Myers Company Production of p-hydroxycephalexin
GB1476981A (en) * 1974-06-05 1977-06-16 Bristol Myers Co Substituted penicillanic acids

Also Published As

Publication number Publication date
JPS52153993A (en) 1977-12-21
US4162314A (en) 1979-07-24
NL7706470A (nl) 1977-12-16
IL52289A0 (en) 1977-08-31
SE7706824L (sv) 1977-12-15
FR2355020A1 (fr) 1978-01-13
AU2550077A (en) 1978-11-30

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