IT1061608B - METHOD FOR THE PREPARATION OF 2.4 DIAMOND 5 ARYLMETHYLPYRIMIDINE AND COMPOUNDS SO OBTAINED - Google Patents
METHOD FOR THE PREPARATION OF 2.4 DIAMOND 5 ARYLMETHYLPYRIMIDINE AND COMPOUNDS SO OBTAINEDInfo
- Publication number
- IT1061608B IT1061608B IT1381760A IT1381760A IT1061608B IT 1061608 B IT1061608 B IT 1061608B IT 1381760 A IT1381760 A IT 1381760A IT 1381760 A IT1381760 A IT 1381760A IT 1061608 B IT1061608 B IT 1061608B
- Authority
- IT
- Italy
- Prior art keywords
- arylmethylpyrimidine
- diamond
- compounds
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3010259A GB957797A (en) | 1959-09-03 | 1959-09-03 | Method for making 2,4-diamino-5-arylmethylpyrimidines and intermediates therefor |
GB3956059 | 1959-11-20 | ||
GB2410160 | 1960-07-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
IT1061608B true IT1061608B (en) | 1983-04-30 |
Family
ID=27258299
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT1381760A IT1061608B (en) | 1959-09-03 | 1960-08-06 | METHOD FOR THE PREPARATION OF 2.4 DIAMOND 5 ARYLMETHYLPYRIMIDINE AND COMPOUNDS SO OBTAINED |
Country Status (7)
Country | Link |
---|---|
AT (1) | AT230379B (en) |
CH (1) | CH418338A (en) |
DE (2) | DE1445176C3 (en) |
FI (1) | FI42960B (en) |
GB (1) | GB957797A (en) |
IT (1) | IT1061608B (en) |
MY (1) | MY6600061A (en) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3485840A (en) * | 1964-11-12 | 1969-12-23 | Hoffmann La Roche | 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes |
US3998814A (en) | 1969-03-06 | 1976-12-21 | Burroughs Wellcome Co. | Process for preparing β-amino-α-benzylacrylonitriles |
US4052553A (en) * | 1969-03-06 | 1977-10-04 | Burroughs Wellcome Co. | 5-benzyl pyrimidines intermediates therefore, and method |
US3855265A (en) * | 1969-03-06 | 1974-12-17 | Burroughs Wellcome Co | 5-benzyl pyrimidines intermediates therefore, and method |
US3950378A (en) * | 1969-03-06 | 1976-04-13 | Burroughs Wellcome Co. | Preparation of β-anilino-α-benzylacrylonitriles |
DE2065367C2 (en) * | 1969-03-06 | 1985-04-04 | The Wellcome Foundation Ltd., London | Process for the preparation of 2,4-diamino-5-benzylpyrimidines |
US3991050A (en) * | 1969-03-06 | 1976-11-09 | Burroughs Wellcome Co. | Preparation of β-Amino-α-benzylacrylonitriles |
US3852276A (en) * | 1969-03-06 | 1974-12-03 | Burroughs Wellcome Co | 5-benzyl pyrimidines intermediate therefore, and method |
GB1261455A (en) * | 1969-03-06 | 1972-01-26 | Burroughs Wellcome Co | Improvements in or relating to substituted acrylonitriles |
BR6915082D0 (en) | 1969-05-16 | 1973-03-08 | Wellcome Found | PROCESS OF PREPARATION OF BENZYL-PYRIMIDINES |
DE2051871A1 (en) * | 1969-05-16 | 1971-11-18 | The Wellcome Foundation Ltd., London | Beta-amino-alpha-aryloxymethylacrylonitrile - and 2,4-diamino-5-benzylpyrimidine derivs. useful as antibacterial agents |
BE789904A (en) * | 1971-10-12 | 1973-04-10 | Wellcome Found | ORGANIC SYNTHESIS PROCESSES |
BE792096A (en) * | 1971-12-01 | 1973-05-30 | Hoffmann La Roche | NEW BENZYLPYRIMIDINES |
US4039543A (en) | 1974-12-24 | 1977-08-02 | Hoffmann-La Roche Inc. | Benzylpyrimidines |
CH624943A5 (en) * | 1977-02-04 | 1981-08-31 | Hoffmann La Roche | |
DE2720771C3 (en) | 1977-05-09 | 1979-11-29 | Ludwig Heumann & Co Gmbh, 8500 Nuernberg | 2,4-Diamino-5- (33-dimethoxy-4thioalkyl-benzyD-pyrimidines, process for their preparation and pharmaceuticals containing these compounds |
EP0046856A3 (en) * | 1980-08-29 | 1982-07-28 | Hüls Troisdorf Aktiengesellschaft | Process for preparing 4-amino-2-mercapto-pyrimidines |
US4438267A (en) * | 1980-11-11 | 1984-03-20 | Daluge Susan M | Monoheteroring compounds and their use |
AT384023B (en) * | 1980-11-11 | 1987-09-25 | Wellcome Found | METHOD FOR PRODUCING NEW 2,4-DIAMINO-5- (SUBST.) PYRIMIDINES AND THEIR SALTS, N-OXIDES AND N-ACYL DERIVATIVES |
HU186413B (en) * | 1981-06-26 | 1985-07-29 | Egyt Gyogyszervegyeszeti Gyar | Process for producing 2,4-diamino-5-bracket-3-comma above,4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine |
HU187370B (en) * | 1981-06-26 | 1985-12-28 | Egyt Gyogyszervegyeszeti Gyar | Improved process for producing 2,4-diamino-5-bracket-3-comma above, 4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine |
DK190983A (en) * | 1982-05-01 | 1983-11-02 | Wellcome Found | 2,4-DIAMINO-5- (SUBSTITUTED) PYRIMIDINES, PROCEDURES FOR THEIR PREPARATION AND INTERMEDIATES |
US4587341A (en) * | 1982-05-07 | 1986-05-06 | Burroughs Wellcome Co. | 2,4-diamino-5-(1,2,3,4-tetrahydro-(substituted or unsubstituted)-6-quinolylmethyl)pyrimidines, useful as antimicrobials |
DE3603577A1 (en) * | 1986-02-06 | 1987-08-13 | Joachim K Prof Dr Seydel | NEW SUBSTITUTED 2,4-DIAMINO-5-BENZYLPYRIMIDINE, THEIR PRODUCTION AND USE THEREOF AS A MEDICINE WITH ANTIBACTERIAL EFFECTIVENESS |
FI895821A0 (en) * | 1988-12-07 | 1989-12-05 | Wellcome Found | PHARMACEUTICAL ACTIVE CNS FOERENINGAR. |
-
0
- DE DENDAT1303727D patent/DE1303727B/en not_active Withdrawn
-
1959
- 1959-09-03 GB GB3010259A patent/GB957797A/en not_active Expired
-
1960
- 1960-08-06 IT IT1381760A patent/IT1061608B/en active
- 1960-08-12 DE DE19601445176 patent/DE1445176C3/en not_active Expired
- 1960-08-29 AT AT656060A patent/AT230379B/en active
- 1960-09-02 CH CH996260A patent/CH418338A/en unknown
- 1960-09-03 FI FI146560A patent/FI42960B/fi active
-
1966
- 1966-12-31 MY MY6600061A patent/MY6600061A/en unknown
Also Published As
Publication number | Publication date |
---|---|
GB957797A (en) | 1964-05-13 |
MY6600061A (en) | 1966-12-31 |
CH418338A (en) | 1966-08-15 |
AT230379B (en) | 1963-12-10 |
DE1445176A1 (en) | 1968-10-17 |
FI42960B (en) | 1970-09-02 |
DE1445176C3 (en) | 1974-04-25 |
DE1445176B2 (en) | 1973-09-06 |
DE1303727B (en) | 1976-02-05 |
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