IN2014MN01939A - - Google Patents

Info

Publication number
IN2014MN01939A
IN2014MN01939A IN1939MUN2014A IN2014MN01939A IN 2014MN01939 A IN2014MN01939 A IN 2014MN01939A IN 1939MUN2014 A IN1939MUN2014 A IN 1939MUN2014A IN 2014MN01939 A IN2014MN01939 A IN 2014MN01939A
Authority
IN
India
Prior art keywords
tissue
trehalose
biological tissue
carried out
treatment
Prior art date
Application number
Inventor
Kiyotaka Iwasaki
Mitsuo Umezu
Original Assignee
Univ Waseda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Waseda filed Critical Univ Waseda
Publication of IN2014MN01939A publication Critical patent/IN2014MN01939A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0094—Gaseous substances
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Abstract

The present invention minimizes any strength reduction or tissue degeneration from before treatment even when a drying treatment or sterilization treatment is carried out for tissue comprising bio derived components and the like. More specifically biological tissue is immersed in a trehalose solution and shaken thereby impregnating the biological tissue with the trehalose solution. The trehalose solution used herein is one obtained by dissolving trehalose in a phosphate buffered physiological saline the concentration of trehalose preferably being in the range of 20 35 wt%. Thereafter a drying treatment for the biological tissue is carried out to remove moisture in the biological tissue and a sterilization treatment for the tissue by ethylene oxide gas sterilization is carried out.
IN1939MUN2014 2012-03-31 2013-04-01 IN2014MN01939A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012083367 2012-03-31
PCT/JP2013/059842 WO2013147299A1 (en) 2012-03-31 2013-04-01 Method for treating biological tissue and biological tissue

Publications (1)

Publication Number Publication Date
IN2014MN01939A true IN2014MN01939A (en) 2015-07-10

Family

ID=49260531

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1939MUN2014 IN2014MN01939A (en) 2012-03-31 2013-04-01

Country Status (8)

Country Link
US (1) US10660977B2 (en)
EP (1) EP2832376B1 (en)
JP (1) JP6078838B2 (en)
CN (1) CN104302329A (en)
AU (1) AU2013240916B2 (en)
ES (1) ES2649904T3 (en)
IN (1) IN2014MN01939A (en)
WO (1) WO2013147299A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106190949B (en) * 2015-05-08 2020-04-10 上海微创心通医疗科技有限公司 Dry animal-derived collagen fiber tissue material, preparation method thereof and bioprosthesis
CN109549761A (en) * 2018-09-12 2019-04-02 沛嘉医疗科技(苏州)有限公司 A kind of bioprosthesis valve and preparation method thereof
JP7432981B2 (en) 2021-10-06 2024-02-19 ＣｏｒｅＴｉｓｓｕｅ ＢｉｏＥｎｇｉｎｅｅｒｉｎｇ株式会社 Container for biological tissue storage
CN114304181B (en) * 2021-12-30 2023-04-21 苏州昊本生物科技有限公司 Sterilizing agent and sterilizing method using same

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Publication number Priority date Publication date Assignee Title
CA2051092C (en) * 1990-09-12 2002-07-23 Stephen A. Livesey Method and apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions
US5336616A (en) * 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
US5334841A (en) * 1993-01-22 1994-08-02 Minnesota Mining And Manufacturing Company Method and apparatus for detecting fluorescence
US6632648B1 (en) * 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
WO1999058082A2 (en) 1998-05-14 1999-11-18 The Cleveland Clinic Foundation Processing of implantable animal tissues for dry storage
US20030068815A1 (en) * 1999-02-11 2003-04-10 Stone Kevin R. Sterilized xenograft tissue
US6866686B2 (en) * 2000-01-28 2005-03-15 Cryolife, Inc. Tissue graft
US6908591B2 (en) * 2002-07-18 2005-06-21 Clearant, Inc. Methods for sterilizing biological materials by irradiation over a temperature gradient
CN100506295C (en) * 2003-05-01 2009-07-01 北京大清生物技术有限公司 Biological derivated bone compound tetracycline slow-release body
EP1633858A4 (en) * 2003-05-30 2006-11-02 Stratatech Corp Room temperature storage of organs
JP2008228744A (en) * 2005-06-23 2008-10-02 Osaka Prefecture Univ Treatment method for preventing transplantation tissue with biological origin from calcification and tissue treated thereby
JP5109030B2 (en) * 2005-07-25 2012-12-26 茂 木下 Sheet-like composition
US9132208B2 (en) 2008-08-07 2015-09-15 Lifenet Health Composition for a tissue repair implant and methods of making the same
CN101626682B (en) * 2006-10-27 2014-04-16 爱德华兹生命科学公司 Biological tissue for surgical implantation
WO2008077155A1 (en) * 2006-12-21 2008-06-26 Genentech, Inc. Sterilization of objects containing biological molecules
US20100291532A1 (en) * 2007-06-12 2010-11-18 Musculoskeletal Transplant Foundation Process for sterilizing acellular soft tissue with irradiation
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
CN101366976B (en) * 2008-09-03 2012-08-29 陕西瑞盛生物科技有限公司 Humanized heterogenous cell epimatrix material and preparation method thereof
JP5424147B2 (en) 2009-06-26 2014-02-26 学校法人早稲田大学 Method and device for holding biological tissue during storage processing, and biological tissue subjected to storage processing
CA2771032A1 (en) * 2009-08-11 2011-02-17 Tissue Banks International Acellular dermal allografts and method of preparation
DK2485779T3 (en) * 2009-10-07 2018-05-07 Kerecis Ehf A FRAME MATERIAL FOR SCREENING AND / OR OTHER TISSUE HEALING APPLICATIONS
JP2013165740A (en) 2010-05-14 2013-08-29 Waseda Univ Decellularization method and artificial tissue for implantation into the human body

Also Published As

Publication number Publication date
AU2013240916B2 (en) 2016-10-27
US20150064228A1 (en) 2015-03-05
CN104302329A (en) 2015-01-21
EP2832376B1 (en) 2017-09-06
AU2013240916A1 (en) 2014-10-16
EP2832376A4 (en) 2015-05-06
ES2649904T3 (en) 2018-01-16
US10660977B2 (en) 2020-05-26
WO2013147299A1 (en) 2013-10-03
JPWO2013147299A1 (en) 2015-12-14
JP6078838B2 (en) 2017-02-15
EP2832376A1 (en) 2015-02-04

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