IN2014KN00742A - - Google Patents
Info
- Publication number
- IN2014KN00742A IN2014KN00742A IN742KON2014A IN2014KN00742A IN 2014KN00742 A IN2014KN00742 A IN 2014KN00742A IN 742KON2014 A IN742KON2014 A IN 742KON2014A IN 2014KN00742 A IN2014KN00742 A IN 2014KN00742A
- Authority
- IN
- India
- Prior art keywords
- tbi
- methods
- tsi
- compositions
- therapeutics
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/723—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/046—Thyroid disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Abstract
Compositions and methods for detecting thyroid hormone blocking immunoglobulin (TBI) are disclosed. The methods are sensitive and specific for TBI and may be used for the dual detection of both TBI and TSI. The compositions and methods are useful for the diagnosis of diseases that are associated with the presence of TBI and/or TSI for monitoring the progress of disease and/or treatment regimens therapeutics vaccines etc. and for assisting clinicians in making treatment decisions.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2011/050976 WO2013036239A1 (en) | 2011-09-09 | 2011-09-09 | Compositions and methods for detecting autoantibodies |
US13/228,705 US8986937B2 (en) | 2011-09-09 | 2011-09-09 | Compositions and methods for detecting autoantibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014KN00742A true IN2014KN00742A (en) | 2015-10-02 |
Family
ID=47830166
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN742KON2014 IN2014KN00742A (en) | 2011-09-09 | 2011-09-09 |
Country Status (9)
Country | Link |
---|---|
US (4) | US8986937B2 (en) |
EP (1) | EP2753928B1 (en) |
JP (1) | JP5908590B2 (en) |
KR (1) | KR101872060B1 (en) |
CN (1) | CN103975239B (en) |
DK (1) | DK2753928T3 (en) |
IN (1) | IN2014KN00742A (en) |
PL (1) | PL2753928T3 (en) |
WO (1) | WO2013036239A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP7211596B2 (en) * | 2018-09-05 | 2023-01-24 | ヤマサ醤油株式会社 | Method and kit for measuring autoantibody activity against TSH receptor |
US20200292543A1 (en) * | 2019-03-12 | 2020-09-17 | Quidel Corporation | Compositions, kits, and methods for detecting autoantibodies |
JP7212955B2 (en) * | 2020-12-28 | 2023-01-26 | ヤマサ醤油株式会社 | Methods and kits for assaying activity of thyroid-stimulating hormone receptor-inhibiting autoantibodies |
CN113686841B (en) * | 2021-09-01 | 2023-06-30 | 北京利德曼生化股份有限公司 | Kit for quantitatively detecting thyroxine binding force, preparation method and detection method thereof |
WO2023214183A2 (en) | 2022-05-06 | 2023-11-09 | Antibody Analytics Limited | Chemically induced proximity systems |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1015601B1 (en) * | 1997-09-19 | 2015-01-07 | Promega Corporation | Thermostable luciferases and methods of production |
US6747139B1 (en) * | 1997-11-05 | 2004-06-08 | Quest Diagnostics Investments, Inc. | Nucleic acid encoding human thyrotropin receptor |
US8563257B2 (en) * | 2000-03-30 | 2013-10-22 | Diagnostic Hybrids, Inc. | Sensitive and rapid methods of using chimeric receptors to identify autoimmune disease and assess disease severity |
US8293879B2 (en) * | 2000-03-30 | 2012-10-23 | Diagnostic Hybrids, Inc. | Methods of using chimeric receptors to identify autoimmune disease |
GB0516527D0 (en) * | 2005-08-11 | 2005-09-21 | Arpi Matossian Rogers | Peptides |
EP1951753A2 (en) * | 2005-11-21 | 2008-08-06 | Dr. Fenning Biomed GmbH | Recombinant polypeptides and methods for detecting and/or quantifying autoantibodies against tsh receptor |
US8840891B2 (en) * | 2007-02-15 | 2014-09-23 | Rsr Limited | Human monoclonal antibodies to the thyrotropin receptor which act as antagonists |
TW200918058A (en) * | 2007-08-31 | 2009-05-01 | Organon Nv | TSH receptor antagonizing tetrahydroquinoline compounds |
US7799532B2 (en) * | 2008-11-12 | 2010-09-21 | Hemopet | Detection and measurement of thyroid hormone autoantibodies |
PL2617734T3 (en) * | 2008-12-24 | 2016-01-29 | Rsr Ltd | Human anti tshr antibodies |
-
2011
- 2011-09-09 DK DK11872018.4T patent/DK2753928T3/en active
- 2011-09-09 JP JP2014529656A patent/JP5908590B2/en active Active
- 2011-09-09 WO PCT/US2011/050976 patent/WO2013036239A1/en active Application Filing
- 2011-09-09 CN CN201180074180.2A patent/CN103975239B/en active Active
- 2011-09-09 EP EP11872018.4A patent/EP2753928B1/en active Active
- 2011-09-09 KR KR1020147009182A patent/KR101872060B1/en active IP Right Grant
- 2011-09-09 PL PL11872018T patent/PL2753928T3/en unknown
- 2011-09-09 IN IN742KON2014 patent/IN2014KN00742A/en unknown
- 2011-09-09 US US13/228,705 patent/US8986937B2/en active Active
-
2015
- 2015-02-18 US US14/625,086 patent/US20150233914A1/en not_active Abandoned
-
2020
- 2020-05-11 US US16/871,554 patent/US20200340991A1/en active Pending
-
2023
- 2023-12-06 US US18/530,800 patent/US20240133882A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20150233914A1 (en) | 2015-08-20 |
US20240133882A1 (en) | 2024-04-25 |
US20200340991A1 (en) | 2020-10-29 |
JP5908590B2 (en) | 2016-04-26 |
US20130065252A1 (en) | 2013-03-14 |
KR20140084022A (en) | 2014-07-04 |
KR101872060B1 (en) | 2018-06-27 |
WO2013036239A1 (en) | 2013-03-14 |
CN103975239A (en) | 2014-08-06 |
JP2014529993A (en) | 2014-11-17 |
EP2753928B1 (en) | 2018-02-07 |
EP2753928A1 (en) | 2014-07-16 |
PL2753928T3 (en) | 2018-07-31 |
DK2753928T3 (en) | 2018-05-22 |
CN103975239B (en) | 2016-08-24 |
US8986937B2 (en) | 2015-03-24 |
EP2753928A4 (en) | 2015-05-27 |
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