IN2014DN09297A - - Google Patents
Info
- Publication number
- IN2014DN09297A IN2014DN09297A IN9297DEN2014A IN2014DN09297A IN 2014DN09297 A IN2014DN09297 A IN 2014DN09297A IN 9297DEN2014 A IN9297DEN2014 A IN 9297DEN2014A IN 2014DN09297 A IN2014DN09297 A IN 2014DN09297A
- Authority
- IN
- India
- Prior art keywords
- nanoparticles
- methods
- octylcyanoacrylate
- exendin
- obesity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Nanotechnology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The disclosure relates to nanoparticles comprising poly(octylcyanoacrylate) for oral administration of a biologically active polypeptide in particular a metabolic peptide such as exendin 4. Also disclosed are methods of producing such nanoparticles pharmaceutical compositions comprising such nanoparticles and methods of treating metabolic disorders such as obesity using such nanoparticles.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261647633P | 2012-05-16 | 2012-05-16 | |
PCT/IB2013/000964 WO2013171570A1 (en) | 2012-05-16 | 2013-05-16 | Polypeptide loaded poca nanoparticles for oral administration |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014DN09297A true IN2014DN09297A (en) | 2015-07-10 |
Family
ID=48577784
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN9297DEN2014 IN2014DN09297A (en) | 2012-05-16 | 2013-05-16 |
Country Status (10)
Country | Link |
---|---|
US (1) | US20150342897A1 (en) |
EP (1) | EP2849775A1 (en) |
JP (1) | JP2015523332A (en) |
KR (1) | KR20150010953A (en) |
CN (1) | CN104411321A (en) |
AU (1) | AU2013261214A1 (en) |
CA (1) | CA2873536A1 (en) |
IN (1) | IN2014DN09297A (en) |
RU (1) | RU2014150850A (en) |
WO (1) | WO2013171570A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104799440B (en) * | 2014-01-23 | 2016-06-08 | 香港纺织及成衣研发中心有限公司 | Improve function clothes and the manufacture method thereof of metabolic syndrome |
CN105342999A (en) * | 2014-08-18 | 2016-02-24 | 山东绿叶制药有限公司 | Exenatide oral nanoparticle |
CN109675020B (en) * | 2019-01-11 | 2021-05-04 | 浙江大学 | Oral GLP-1 polypeptide nano preparation and preparation method and application thereof |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3262329B2 (en) | 1990-01-24 | 2002-03-04 | アイ. バックレイ,ダグラス | GLP-1 analog useful for the treatment of diabetes |
IE80468B1 (en) * | 1995-04-04 | 1998-07-29 | Elan Corp Plc | Controlled release biodegradable nanoparticles containing insulin |
CA2262647C (en) | 1996-08-08 | 2007-12-04 | Amylin Pharmaceuticals, Inc. | Methods for regulating gastrointestinal motility |
DK1019077T4 (en) | 1997-08-08 | 2011-03-07 | Amylin Pharmaceuticals Inc | New exendin agonist compounds |
EP1032587B2 (en) | 1997-11-14 | 2013-03-13 | Amylin Pharmaceuticals, Inc. | Novel exendin agonist compounds |
EP1066314B1 (en) | 1997-11-14 | 2007-12-26 | Amylin Pharmaceuticals, Inc. | Novel exendin agonist compounds |
WO1999040788A1 (en) | 1998-02-13 | 1999-08-19 | Amylin Pharmaceuticals, Inc. | Inotropic and diuretic effects of exendin and glp-1 |
EP1056775B1 (en) | 1998-02-27 | 2010-04-28 | Novo Nordisk A/S | Glp-1 derivatives of glp-1 and exendin with protracted profile of action |
AU2002226897B2 (en) | 2000-12-07 | 2007-10-25 | Eli Lilly And Company | GLP-1 fusion proteins |
CA2484556A1 (en) | 2001-12-21 | 2003-07-24 | Human Genome Sciences, Inc. | Albumin fusion proteins |
ES2500918T3 (en) | 2001-12-21 | 2014-10-01 | Human Genome Sciences, Inc. | Albumin and interferon beta fusion proteins |
CA2513213C (en) | 2003-01-22 | 2013-07-30 | Human Genome Sciences, Inc. | Albumin fusion proteins |
SI2932981T1 (en) | 2003-09-19 | 2021-11-30 | Novo Nordisk A/S | Albumin-binding derivatives of GLP-1 |
US7456254B2 (en) * | 2004-04-15 | 2008-11-25 | Alkermes, Inc. | Polymer-based sustained release device |
US20110182805A1 (en) | 2005-06-17 | 2011-07-28 | Desimone Joseph M | Nanoparticle fabrication methods, systems, and materials |
US20080138418A1 (en) * | 2006-12-07 | 2008-06-12 | Tong Shen Enterprise Co., Ltd. | Nanoparticles composed of alkyl-cyanoacrylate polymers |
EP3560672A1 (en) | 2007-10-12 | 2019-10-30 | Liquidia Technologies, Inc. | Method for producing particles |
-
2013
- 2013-05-16 RU RU2014150850A patent/RU2014150850A/en not_active Application Discontinuation
- 2013-05-16 CN CN201380031679.4A patent/CN104411321A/en active Pending
- 2013-05-16 US US14/401,333 patent/US20150342897A1/en not_active Abandoned
- 2013-05-16 KR KR20147031771A patent/KR20150010953A/en not_active Application Discontinuation
- 2013-05-16 WO PCT/IB2013/000964 patent/WO2013171570A1/en active Application Filing
- 2013-05-16 IN IN9297DEN2014 patent/IN2014DN09297A/en unknown
- 2013-05-16 CA CA2873536A patent/CA2873536A1/en not_active Abandoned
- 2013-05-16 AU AU2013261214A patent/AU2013261214A1/en not_active Abandoned
- 2013-05-16 JP JP2015512144A patent/JP2015523332A/en active Pending
- 2013-05-16 EP EP13727643.2A patent/EP2849775A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2873536A1 (en) | 2013-11-21 |
CN104411321A (en) | 2015-03-11 |
AU2013261214A1 (en) | 2014-11-20 |
JP2015523332A (en) | 2015-08-13 |
KR20150010953A (en) | 2015-01-29 |
EP2849775A1 (en) | 2015-03-25 |
WO2013171570A1 (en) | 2013-11-21 |
US20150342897A1 (en) | 2015-12-03 |
RU2014150850A (en) | 2016-07-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IN2014MN02132A (en) | ||
MX2014015258A (en) | Fibroblast growth factor 21 variants. | |
TN2014000096A1 (en) | Fibroblast growth factor 21 variants | |
IN2014KN02830A (en) | ||
MX344238B (en) | Tetrazole compounds and methods of making and using same. | |
MX2013008851A (en) | Compostions and methods for treating chronic inflammation and inflammatory diseases. | |
EP3682875A3 (en) | Methods of treating pediatric metabolic syndrome | |
UA109991C2 (en) | CARBAMATE COMPOUNDS, THEIR PREPARATION AND APPLICATION | |
MX2012007806A (en) | Pharmaceutical compositions for oral administration of insulin peptides. | |
IN2012DN06720A (en) | ||
WO2012098562A3 (en) | Liquid oral compositions of lanthanum salts | |
WO2011084808A3 (en) | Bifunctional polypeptide compositions and methods for treatment of metabolic and cardiovascular diseases | |
WO2011141685A3 (en) | Systemic nasal compositions comprising cocoyl proline or at least one of the constituents thereof | |
MX2019003619A (en) | Bromocriptine formulations. | |
UA113962C2 (en) | PHARMACEUTICAL COMPOSITION CONTAINING APOMORPHINE AS AN ACTIVE INGREDIENT | |
TN2014000046A1 (en) | Substituted 3-(biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one | |
IN2012DN00239A (en) | ||
TN2015000267A1 (en) | Solid unit with high fexofenadine content and process for the preparation thereof | |
IN2014DN09297A (en) | ||
IN2014MN02156A (en) | ||
WO2014039074A3 (en) | Therapeutic compositions and related methods | |
IL230751A0 (en) | Novel peptides,compositions comprising the same and uses thereof in methods for the treatment of metabolic ,cardiac and immune related disorders | |
PH12014501352A1 (en) | Non-enteric pharmaceutical composition comprising crofelemer | |
UA112981C2 (en) | OPTION OF HUMAN GDNF | |
WO2013038200A3 (en) | Neurodevelopmental disorders |