IN2014DN06711A - - Google Patents

Info

Publication number
IN2014DN06711A
IN2014DN06711A IN6711DEN2014A IN2014DN06711A IN 2014DN06711 A IN2014DN06711 A IN 2014DN06711A IN 6711DEN2014 A IN6711DEN2014 A IN 6711DEN2014A IN 2014DN06711 A IN2014DN06711 A IN 2014DN06711A
Authority
IN
India
Application number
Inventor
Steven Hoffman
Original Assignee
Tyme Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/371,076 external-priority patent/US8481498B1/en
Application filed by Tyme Inc filed Critical Tyme Inc
Publication of IN2014DN06711A publication Critical patent/IN2014DN06711A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/31Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37Coumarins, e.g. psoralen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41661,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/33Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A61K38/34Melanocyte stimulating hormone [MSH], e.g. alpha- or beta-melanotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
IN6711DEN2014 2012-01-17 2014-08-11 IN2014DN06711A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261587420P 2012-01-17 2012-01-17
US13/371,076 US8481498B1 (en) 2012-01-17 2012-02-10 Pharmaceutical compositions and methods
US201261702994P 2012-09-19 2012-09-19
PCT/US2013/021714 WO2013109610A1 (en) 2012-01-17 2013-01-16 Pharmaceutical compositions and methods

Publications (1)

Publication Number Publication Date
IN2014DN06711A true IN2014DN06711A (en) 2015-05-22

Family

ID=48799616

Family Applications (1)

Application Number Title Priority Date Filing Date
IN6711DEN2014 IN2014DN06711A (en) 2012-01-17 2014-08-11

Country Status (24)

Country Link
EP (2) EP2804599B1 (en)
JP (4) JP6276707B2 (en)
KR (1) KR102172658B1 (en)
CN (2) CN104220057B (en)
AU (4) AU2013209862A1 (en)
BR (1) BR112014017613A2 (en)
CA (1) CA2862689C (en)
CY (1) CY1121450T1 (en)
DK (1) DK2804599T3 (en)
ES (1) ES2706070T3 (en)
HR (1) HRP20190046T1 (en)
HU (1) HUE045314T2 (en)
IL (2) IL233681B (en)
IN (1) IN2014DN06711A (en)
LT (1) LT2804599T (en)
MX (1) MX363579B (en)
NZ (2) NZ721280A (en)
PH (1) PH12014501639A1 (en)
PL (1) PL2804599T3 (en)
PT (1) PT2804599T (en)
RS (1) RS58538B1 (en)
SI (1) SI2804599T1 (en)
WO (1) WO2013109610A1 (en)
ZA (1) ZA201405611B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2804599T (en) * 2012-01-17 2019-04-10 Tyme, Inc. Combination therapy for the treatment of cancer
US10272068B2 (en) 2012-01-17 2019-04-30 Tyme, Inc. Pharmaceutical compositions and methods
US20130183263A1 (en) 2012-01-17 2013-07-18 Steven Hoffman Pharmaceutical compositions and methods
US10646552B2 (en) 2012-01-17 2020-05-12 Tyme, Inc. Pharmaceutical compositions and methods
US9585841B2 (en) * 2013-10-22 2017-03-07 Tyme, Inc. Tyrosine derivatives and compositions comprising them
US9724657B2 (en) 2013-10-22 2017-08-08 Tyme, Inc. High-speed centrifugal mixing devices and methods of use
AU2015371253B2 (en) * 2014-12-23 2020-07-23 Steven Hoffman Transdermal formulations
US9687528B2 (en) 2014-12-23 2017-06-27 Steven Hoffman Transdermal formulations
US20190091252A1 (en) * 2016-03-15 2019-03-28 Tyme, Inc. Pharmaceutical compositions for the treatment of cancer
AU2017268351A1 (en) * 2016-05-18 2018-12-06 Tyme, Inc. Dihydrotestosterone and dihydrotestosterone derivatives and promoters in the treatment of cancer
CN110167580A (en) * 2016-11-15 2019-08-23 迪美公司 Pharmaceutical composition and method for treating cancer
WO2018102506A1 (en) * 2016-11-30 2018-06-07 Tyme, Inc. Tyrosine derivatives and compositions comprising them
JP7171611B2 (en) * 2017-04-21 2022-11-15 スティーブン・ホフマン Compositions and methods for treating retinopathy
JP2022532210A (en) * 2019-05-14 2022-07-13 タイム,インコーポレーテッド Compositions and Methods for Treating Cancer
JP2022553175A (en) * 2019-10-15 2022-12-22 タイム,インコーポレーテッド Alkyl ester of α-methyl-DL-tyrosine for use in treating cancer
CN115515575A (en) * 2020-01-17 2022-12-23 迪美公司 Tyrosine derivatives for the modulation of cancer
US10905698B1 (en) 2020-05-14 2021-02-02 Tyme, Inc. Methods of treating SARS-COV-2 infections
CN116783212A (en) * 2020-12-02 2023-09-19 霍夫曼技术有限责任公司 Compositions and methods for modulating cancer in non-human mammals

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
DE3823735A1 (en) * 1988-07-13 1989-03-02 Ernst Hajek Use of D-leucine (dextrorotatory alpha -amino isocaproic acid) as active substance for controlling malignant tumours of the mucosal epithelium of the entire intestinal tract including the pancreas and gall bladder
US5225435A (en) 1990-05-18 1993-07-06 Yale University Soluble melanin
IT1291633B1 (en) * 1997-04-22 1999-01-11 Pharmaconsult S A S USE OF ALPHA-METHYL-P-THYROSINE TO INHIBIT THE PRODUCTION OF MELANIN IN THE MELANOCYTES OF THE IRIS
IL138214A0 (en) * 1998-03-09 2001-10-31 Zealand Pharmaceuticals As Pharmacolgically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
WO2000010507A2 (en) 1998-08-21 2000-03-02 The Children's Medical Center Corporation Use of melanin for inhibition of angiogenesis and macular degeneration
JP2002128304A (en) 2000-10-20 2002-05-09 Nec Eng Ltd Paper feeder
KR20110120981A (en) * 2002-12-26 2011-11-04 아지노모토 가부시키가이샤 Inhibitor for liver cancer onset and progress
ES2327421T3 (en) * 2005-03-11 2009-10-29 Gpc Biotech Ag COMBINED ANTIPROLIFERATIVE THERAPY THAT INCLUDES SATRAPLATINO OR JM118 AND DOCETAXEL.
CA2661024A1 (en) * 2006-08-28 2008-03-06 The Regents Of The University Of California Small molecule potentiator of hormonal therapy for breast cancer
JP5073541B2 (en) 2007-05-09 2012-11-14 ルネサスエレクトロニクス株式会社 Semiconductor memory device
EP2187901B1 (en) * 2007-09-11 2012-08-08 Mondobiotech Laboratories AG Neuropeptide El optionally combined with ACTH (7-38) for use in anti-angiogenic therapy
US8110578B2 (en) * 2008-10-27 2012-02-07 Signal Pharmaceuticals, Llc Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway
AU2011241175A1 (en) * 2010-04-16 2012-11-29 Davos Life Science Pte. Ltd. Synergistic interaction of at least one Vitamin E component and tyrosinase inhibitors for dermatological applications
LT2804599T (en) * 2012-01-17 2019-04-10 Tyme, Inc. Combination therapy for the treatment of cancer

Also Published As

Publication number Publication date
IL252566A0 (en) 2017-07-31
NZ628757A (en) 2016-07-29
BR112014017613A2 (en) 2017-07-04
MX2014008640A (en) 2015-03-09
JP2018065848A (en) 2018-04-26
AU2022202113A1 (en) 2022-04-14
SI2804599T1 (en) 2019-05-31
AU2013209862A1 (en) 2014-09-04
KR20140135704A (en) 2014-11-26
IL233681B (en) 2019-07-31
JP6789916B2 (en) 2020-11-25
EP2804599B1 (en) 2018-10-17
EP2804599A1 (en) 2014-11-26
LT2804599T (en) 2019-04-10
RS58538B1 (en) 2019-04-30
PH12014501639A1 (en) 2014-10-13
HRP20190046T1 (en) 2019-05-03
ES2706070T3 (en) 2019-03-27
MX363579B (en) 2019-03-27
JP2020172521A (en) 2020-10-22
PL2804599T3 (en) 2019-06-28
CA2862689C (en) 2020-03-10
JP6276707B2 (en) 2018-02-07
KR102172658B1 (en) 2020-11-02
AU2018203026A1 (en) 2018-05-17
WO2013109610A1 (en) 2013-07-25
EP2804599A4 (en) 2015-10-21
CN107714684A (en) 2018-02-23
AU2020201683A1 (en) 2020-03-26
CN104220057A (en) 2014-12-17
CN104220057B (en) 2017-11-03
JP2022095894A (en) 2022-06-28
CA2862689A1 (en) 2013-07-25
CY1121450T1 (en) 2020-05-29
DK2804599T3 (en) 2019-02-04
ZA201405611B (en) 2015-06-24
EP3488848A1 (en) 2019-05-29
JP7095028B2 (en) 2022-07-04
PT2804599T (en) 2019-01-28
HUE045314T2 (en) 2019-12-30
IL252566B (en) 2020-07-30
IL233681A0 (en) 2014-09-30
JP2015509101A (en) 2015-03-26
NZ721280A (en) 2017-08-25

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