IN2014DN03014A - - Google Patents

Info

Publication number
IN2014DN03014A
IN2014DN03014A IN3014DEN2014A IN2014DN03014A IN 2014DN03014 A IN2014DN03014 A IN 2014DN03014A IN 3014DEN2014 A IN3014DEN2014 A IN 3014DEN2014A IN 2014DN03014 A IN2014DN03014 A IN 2014DN03014A
Authority
IN
India
Prior art keywords
laser speckle
anisotropic
blood flow
pixel
primary pixel
Prior art date
Application number
Inventor
Abhishek Rege
Janaka Senarathna
Nitish V Thakor
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Publication of IN2014DN03014A publication Critical patent/IN2014DN03014A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A61B5/0261—Measuring blood flow using optical means, e.g. infrared light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0042—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4887—Locating particular structures in or on the body
    • A61B5/489—Blood vessels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Eye Examination Apparatus (AREA)
  • Image Processing (AREA)

Abstract

An embodiment in accordance with the present invention provides a system and method for imaging living tissue and processing laser speckle data anisotropically to calculate laser speckle contrast preferentially along the direction of blood flow. In the present invention raw laser speckle images are obtained and processed resulting in the anisotropic laser speckle images The system and method involve the determination of the direction of blood flow for every pixel within the region of interest (primary pixel) and subsequent extraction of a set of secondary pixels in the spatio temporal neighborhood of the primary pixel that is anisotropic in the direction of blood flow. Speckle contrast is then calculated for every primary pixel as the ratio of standard deviation and mean of all secondary pixels in this anisotropic neighborhood and collectively plotted using a suitable color mapping scheme to obtain an anisotropic laser speckle contrast image of the region of interest.
IN3014DEN2014 2011-09-26 2012-09-26 IN2014DN03014A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161539042P 2011-09-26 2011-09-26
PCT/US2012/057221 WO2013049123A1 (en) 2011-09-26 2012-09-26 Anisotropic processing of laser speckle images

Publications (1)

Publication Number Publication Date
IN2014DN03014A true IN2014DN03014A (en) 2015-05-08

Family

ID=47996353

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3014DEN2014 IN2014DN03014A (en) 2011-09-26 2012-09-26

Country Status (5)

Country Link
US (1) US10045703B2 (en)
EP (1) EP2760338B1 (en)
CN (1) CN103857335B (en)
IN (1) IN2014DN03014A (en)
WO (1) WO2013049123A1 (en)

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* Cited by examiner, † Cited by third party
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WO2014151114A1 (en) 2013-03-15 2014-09-25 Vasoptic Medical Inc. Ophthalmic examination and disease management with multiple illumination modalities
JP6394367B2 (en) * 2014-05-30 2018-09-26 ソニー株式会社 Fluid analysis apparatus, fluid analysis method, program, and fluid analysis system
CN104173038B (en) * 2014-08-29 2016-04-20 上海交通大学 Based on the blood flow velocity measurement method of frequency domain laser speckle imaging
US9996921B2 (en) 2015-05-17 2018-06-12 LIGHTLAB IMAGING, lNC. Detection of metal stent struts
US10109058B2 (en) 2015-05-17 2018-10-23 Lightlab Imaging, Inc. Intravascular imaging system interfaces and stent detection methods
IL239113A (en) 2015-06-01 2016-12-29 Elbit Systems Land & C4I Ltd System and method for determining audio characteristics from within a body
WO2017019634A1 (en) 2015-07-25 2017-02-02 Lightlab Imaging, Inc. Intravascular data visualization method
AU2016297923B2 (en) * 2015-07-25 2021-02-18 Lightlab Imaging, Inc. Guidewire detection systems, methods, and apparatuses
DE102015114376B4 (en) * 2015-08-28 2017-10-12 Visteon Global Technologies, Inc. Apparatus and method for characterizing subjective speckle formation
JP2019502423A (en) * 2015-11-13 2019-01-31 ラトガース， ザ ステイト ユニバーシティー オブ ニュージャージー Differential diagnosis of periapical diseases based on image analysis results
EP3385723B1 (en) * 2015-12-04 2020-12-02 Sony Corporation Information processing device, speckle imaging system, and information processing method
JP6852730B2 (en) 2016-04-05 2021-03-31 ソニー株式会社 Speckle measuring device and speckle measuring method
KR102527671B1 (en) * 2016-06-27 2023-05-02 옴리 워샤브스키 Color imaging by synchronized illumination in discrete narrow bands
CN106419890B (en) * 2016-11-14 2024-04-30 佛山科学技术学院 Blood flow velocity measuring device and method based on space-time modulation
FR3062542B1 (en) * 2017-02-01 2020-12-25 Office National Detudes Rech Aerospatiales APPARATUS AND PROCESS FOR SCAR CONTRAST IMAGING
CN110507305B (en) * 2019-08-27 2024-04-16 北京大学 Blood flow velocity measurement method based on laser speckle contrast waveform conduction time difference
JP2021058478A (en) * 2019-10-08 2021-04-15 ソニー株式会社 Image processing apparatus, image processing system, and image processing method
CN111369627B (en) * 2020-03-05 2023-04-07 电子科技大学 Non-invasive speckle directional imaging method
WO2021183637A1 (en) 2020-03-13 2021-09-16 Vasoptic Medical Inc. Illumination of an eye fundus using non-scanning coherent light
CN111436905B (en) * 2020-04-03 2024-03-19 图湃(北京)医疗科技有限公司 Optical coherence tomography angiography method and device
CN112611701B (en) * 2020-12-10 2023-02-28 天津大学 Circulating tumor cell detection device based on dynamic coherent optical imaging technology
CN118234425A (en) * 2021-07-09 2024-06-21 范德堡大学 Laser speckle contrast imaging system and application thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101406392B (en) * 1999-09-24 2011-05-18 加拿大国家研究委员会 Apparatus for performing intra-operative angiography
US7113817B1 (en) * 2001-10-04 2006-09-26 Wintec, Llc Optical imaging of blood circulation velocities
US7660461B2 (en) * 2006-04-21 2010-02-09 Sectra Ab Automated histogram characterization of data sets for image visualization using alpha-histograms
WO2009008745A2 (en) 2007-07-06 2009-01-15 Industrial Research Limited Laser speckle imaging systems and methods
WO2009039303A1 (en) * 2007-09-19 2009-03-26 State University Of New York At Stony Brook Optical coherence tomography systems and methods
CN101566504B (en) * 2008-04-25 2011-06-29 北京中视中科光电技术有限公司 Method and device for measuring laser speckles
WO2010096447A2 (en) * 2009-02-17 2010-08-26 Board Of Regents, The University Of Texas System Quantitative imaging with multi-exposure speckle imaging (mesi)

Also Published As

Publication number Publication date
EP2760338A1 (en) 2014-08-06
CN103857335B (en) 2016-01-27
EP2760338B1 (en) 2018-08-22
CN103857335A (en) 2014-06-11
WO2013049123A1 (en) 2013-04-04
US20140316284A1 (en) 2014-10-23
US10045703B2 (en) 2018-08-14
EP2760338A4 (en) 2015-06-24

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